3GV8
 
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3GV5
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3V3X
 | | Nitroxide Spin Labels in Protein GB1: N8/K28 Double Mutant | | 分子名称: | ACETATE ION, GLYCEROL, Immunoglobulin G-binding protein G, ... | | 著者 | Cunningham, T.F, McGoff, M.S, Sengupta, I, Jaroniec, C.P, Horne, W.S, Saxena, S.K. | | 登録日 | 2011-12-14 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | High-resolution structure of a protein spin-label in a solvent-exposed beta-sheet and comparison with DEER spectroscopy.
Biochemistry, 51, 2012
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3Q8Q
 | | Human DNA polymerase iota incorporating dATP opposite 8-oxo-guanine | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*AP*(8OG)P*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... | | 著者 | Kirouac, K.N, Ling, H. | | 登録日 | 2011-01-06 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.031 Å) | | 主引用文献 | Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota.
Proc.Natl.Acad.Sci.USA, 108, 2011
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4FS2
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3G6X
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3Q8S
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6WFW
 | | Crystal structure of Fab364 in complex with NPNA2 peptide from circumsporozoite protein | | 分子名称: | Fab364 heavy chain, Fab364 light chain, Immunoglobulin G-binding protein G, ... | | 著者 | Pholcharee, T, Oyen, D, Wilson, I.A. | | 登録日 | 2020-04-04 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | | 主引用文献 | Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
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4EBE
 | | Conformationally Restrained North-methanocarba-2'-deoxyadenosine Corrects the Error-Prone Nature of Human DNA Polymerase Iota | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(P*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(P*CP*TP*GP*GP*GP*TP*CP*CP*T)-3', ... | | 著者 | Eoff, R.L, Ketkar, A, Banerjee, S. | | 登録日 | 2012-03-23 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Nucleotide-Analogue-Induced Gain of Function Corrects the Error-Prone Nature of Human DNA Polymerase iota.
J.Am.Chem.Soc., 134, 2012
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3G6Y
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5HI1
 | | Backbone Modifications in the Protein GB1 Helix: Aib24, beta-3-Lys28, beta-3-Lys31, Aib35 | | 分子名称: | ACETATE ION, Immunoglobulin G-binding protein G | | 著者 | Tavenor, N.A, Reinert, Z.E, Lengyel, G.A, Griffith, B.D, Horne, W.S. | | 登録日 | 2016-01-11 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Comparison of design strategies for alpha-helix backbone modification in a protein tertiary fold.
Chem.Commun.(Camb.), 52, 2016
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4WH4
 | | Protein GB1 Quadruple Mutant I6H/N8H/K28H/Q32H | | 分子名称: | GLYCEROL, Immunoglobulin G-binding protein G, SULFATE ION | | 著者 | Cunningham, T.C, Horne, W.S, Saxena, S. | | 登録日 | 2014-09-19 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The double-histidine Cu2+-binding motif: a highly rigid, site-specific spin probe for electron spin resonance distance measurements.
Angew.Chem.Int.Ed.Engl., 54, 2015
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1UWX
 | | P1.2 serosubtype antigen derived from N. meningitidis PorA in complex with Fab fragment | | 分子名称: | ANTIBODY, CLASS 1 OUTER MEMBRANE PROTEIN VARIABLE REGION 2, PROTEIN G-PRIME | | 著者 | Tzitzilonis, C, Prince, S.M, Collins, R.F, Maiden, M.C.J, Feavers, I.M, Derrick, J.P. | | 登録日 | 2004-02-12 | | 公開日 | 2005-06-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Variation and Immune Recognition of the P1.2 Subtype Meningococcal Antigen.
Proteins: Struct., Funct., Bioinf., 62, 2005
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3G6V
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5BMG
 | | Nitroxide Spin Labels in Protein GB1: E15 Mutant | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Immunoglobulin G-binding protein G, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | | 著者 | Cunningham, T.C, Horne, W.S, Saxena, S. | | 登録日 | 2015-05-22 | | 公開日 | 2016-04-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Rotameric preferences of a protein spin label at edge-strand beta-sheet sites.
Protein Sci., 25, 2016
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3GV7
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3H4D
 | | Ternary complex of human DNA polymerase iota with template U/T and incoming dGTP | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC)), 5'-D(*TP*(BRU)P*GP*GP*GP*TP*CP*CP*T), ... | | 著者 | Jain, R, Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | | 登録日 | 2009-04-18 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Replication across template T/U by human DNA polymerase-iota.
Structure, 17, 2009
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4OZA
 | | Backbone Modifications in the Protein GB1 Helix: beta-3-Ala24, beta-3-Lys28, beta-3-Gln32, beta-3-Asp36 | | 分子名称: | ISOPROPYL ALCOHOL, Streptococcal Protein GB1 Backbone Modified Variant: beta-3-Ala24, beta-3-Lys28, ... | | 著者 | Reinert, Z.E, Horne, W.S. | | 登録日 | 2014-02-14 | | 公開日 | 2014-07-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Folding Thermodynamics of Protein-Like Oligomers with Heterogeneous Backbones.
Chem Sci, 5, 2014
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6NLB
 | | Crystal structure of de novo designed metal-controlled dimer of mutant B1 immunoglobulin-binding domain of Streptococcal Protein G (L12H, E15V, T16L, T18I, V29H, Y33H, N37L)-apo | | 分子名称: | Immunoglobulin G-binding protein G, MAGNESIUM ION | | 著者 | Maniaci, B, Stec, B, Huxford, T. | | 登録日 | 2019-01-08 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Design of High-Affinity Metal-Controlled Protein Dimers.
Biochemistry, 58, 2019
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1ZET
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1T3N
 | | Structure of the catalytic core of DNA polymerase Iota in complex with DNA and dTTP | | 分子名称: | MAGNESIUM ION, Primer DNA strand, THYMIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Nair, D.T, Johnson, R.E, Prakash, S, Prakash, L, Aggarwal, A.K. | | 登録日 | 2004-04-27 | | 公開日 | 2004-07-20 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing.
Nature, 430, 2004
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2DPI
 | | Ternary complex of hPoli with DNA and dCTP | | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(EDA)P*GP*GP*GP*TP*CP*CP*T)-3', ... | | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | | 登録日 | 2006-05-12 | | 公開日 | 2006-07-04 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Hoogsteen base pair formation promotes synthesis opposite the 1,N(6)-ethenodeoxyadenosine lesion by human DNA polymerase iota.
Nat.Struct.Mol.Biol., 13, 2006
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3H40
 | | Binary complex of human DNA polymerase iota with template U/T | | 分子名称: | 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(BRU)P*GP*GP*GP*TP*CP*CP*T)-3', DNA polymerase iota, ... | | 著者 | Jain, R, Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | | 登録日 | 2009-04-17 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Replication across template T/U by human DNA polymerase-iota.
Structure, 17, 2009
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2DPJ
 | | structure of hPoli with DNA and dTTP | | 分子名称: | 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(EDA)P*GP*GP*GP*TP*CP*CP*T)-3', DNA polymerase iota, ... | | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | | 登録日 | 2006-05-12 | | 公開日 | 2006-07-04 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Hoogsteen base pair formation promotes synthesis opposite the 1,N(6)-ethenodeoxyadenosine lesion by human DNA polymerase iota.
Nat.Struct.Mol.Biol., 13, 2006
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4OZC
 | | Backbone Modifications in the Protein GB1 Helix and Loops: beta-ACPC21, beta-ACPC24, beta-3-Lys28, beta-3-Lys31, beta-ACPC35, beta-ACPC40 | | 分子名称: | GLYCEROL, SULFATE ION, Streptococcal Protein GB1 Backbone Modified Variant: beta-ACPC21, ... | | 著者 | Reinert, Z.E, Horne, W.S. | | 登録日 | 2014-02-14 | | 公開日 | 2014-07-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Folding Thermodynamics of Protein-Like Oligomers with Heterogeneous Backbones.
Chem Sci, 5, 2014
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