7FET
 
 | | SARS-CoV-2 B.1.1.7 Spike Glycoprotein trimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Wen, Z.L, Zhu, Y, Sun, F. | | 登録日 | 2021-07-21 | | 公開日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B.1.1.7 variant (Alpha).
Cell Discov, 7, 2021
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7KJ3
 | | SARS-CoV-2 Spike Glycoprotein with two ACE2 Bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B. | | 登録日 | 2020-10-25 | | 公開日 | 2020-11-11 | | 最終更新日 | 2021-02-24 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent.
Nat.Struct.Mol.Biol., 28, 2021
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7VNC
 | | Structure of the SARS-CoV-2 spike glycoprotein in complex with a human single domain antibody n3113 (UDD-state, state 1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yang, Z, Wang, Y, Kong, Y, Jin, Y, Wu, Y, Ying, T. | | 登録日 | 2021-10-10 | | 公開日 | 2021-11-24 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants.
Signal Transduct Target Ther, 6, 2021
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7FB1
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7MLZ
 | | Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain | | 分子名称: | B1-182.1 Fab heavy chain, B1-182.1 Fab light chain, Spike protein S1, ... | | 著者 | Zhou, T, Tsybovsky, T, Kwong, P.D. | | 登録日 | 2021-04-29 | | 公開日 | 2021-07-28 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Science, 373, 2021
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7WP0
 | | Cryo-EM structure of SARS-CoV-2 Delta S6P trimer in complex with neutralizing antibody VacW-209 (local refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c335_light_IGLV1-40_IGLJ3, Spike protein S1, ... | | 著者 | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | | 登録日 | 2022-01-22 | | 公開日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209.
Cell Res., 32, 2022
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7N9C
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7YQX
 | | SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, ... | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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8FEZ
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7TP2
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8X5R
 | | SARS-CoV-2 BA.2.75 Spike with K356T mutation (1 RBD up) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Yue, C, Liu, P. | | 登録日 | 2023-11-17 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity
Natl Sci Rev, 2024
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7FDH
 | | SARS-COV-2 Spike RBDMACSp25 binding to hACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | | 著者 | Wang, X, Cao, L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-25 | | 最終更新日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2.
Nat Commun, 12, 2021
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7LSS
 | | Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2-7 variable heavy chain, ... | | 著者 | Rapp, M, Shapiro, L. | | 登録日 | 2021-02-18 | | 公開日 | 2021-03-17 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies.
Structure, 29, 2021
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7LYL
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7YBJ
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7YEG
 | | SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | | 登録日 | 2022-07-05 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
Nat Microbiol, 7, 2022
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7ME7
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8EYG
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8GNH
 | | Complex structure of BD-218 and Spike protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of BD-218, ... | | 著者 | Wang, B, Xu, H, Su, X.D. | | 登録日 | 2022-08-23 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Human antibody BD-218 has broad neutralizing activity against concerning variants of SARS-CoV-2.
Int.J.Biol.Macromol., 227, 2023
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7YQY
 | | SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, ... | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7YCY
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7XIZ
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7KNH
 | | Cryo-EM Structure of Double ACE2-Bound SARS-CoV-2 Trimer Spike at pH 5.5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L. | | 登録日 | 2020-11-04 | | 公開日 | 2020-12-16 | | 最終更新日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
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8TAZ
 | | Cryo-EM structure of mink variant Y453F trimeric spike protein bound to one mink ACE2 receptors | | 分子名称: | Angiotensin-converting enzyme, Spike glycoprotein | | 著者 | Ahn, H.M, Calderon, B, Fan, X, Gao, Y, Horgan, N, Liang, B. | | 登録日 | 2023-06-28 | | 公開日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2.
J Med Virol, 95, 2023
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8EYH
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