7C8W
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![BU of 7c8w by Molmil](/molmil-images/mine/7c8w) | Structure of sybody MR17 in complex with the SARS-CoV-2 S receptor-binding domain (RBD) | 分子名称: | GLYCEROL, Spike protein S1, Synthetic nanobody MR17, ... | 著者 | Li, T, Cai, H, Yao, H, Qin, W, Li, D. | 登録日 | 2020-06-03 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection. Nat Commun, 12, 2021
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8EOO
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![BU of 8eoo by Molmil](/molmil-images/mine/8eoo) | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibodies WRAIR-2063 and WRAIR-2151 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ... | 著者 | Jensen, J.L, Sankhala, R.S, Joyce, M.G. | 登録日 | 2022-10-03 | 公開日 | 2023-06-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity. J.Virol., 97, 2023
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8HHY
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![BU of 8hhy by Molmil](/molmil-images/mine/8hhy) | SARS-CoV-2 Delta Spike in complex with IS-9A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IS-9A Fab heavy chain, ... | 著者 | Mohapatra, A, Wu, Y.-M. | 登録日 | 2022-11-17 | 公開日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2. Nat Commun, 14, 2023
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7WPA
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![BU of 7wpa by Molmil](/molmil-images/mine/7wpa) | SARS-CoV-2 Omicron Variant SPIKE trimer complexed with ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Yin, W, Xu, Y, Xu, P, Cao, X, Wu, C, Gu, C, He, X, Wang, X, Huang, S, Yuan, Q, Wu, K, Hu, W, Huang, Z, Liu, J, Wang, Z, Jia, F, Xia, K, Liu, P, Wang, X, Song, B, Zheng, J, Jiang, H, Cheng, X, Jiang, Y, Deng, S, Xu, E. | 登録日 | 2022-01-23 | 公開日 | 2022-03-09 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody. Science, 375, 2022
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8DLQ
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![BU of 8dlq by Molmil](/molmil-images/mine/8dlq) | Cryo-EM structure of SARS-CoV-2 Gamma (P.1) spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization. Nat Commun, 13, 2022
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8DM6
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![BU of 8dm6 by Molmil](/molmil-images/mine/8dm6) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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8VKP
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![BU of 8vkp by Molmil](/molmil-images/mine/8vkp) | Cryo-EM structure of SARS-CoV-2 XBB.1.5 spike protein in complex with human ACE2 (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Zhu, X, Mannar, D, Saville, J, Poloni, C, Bezeruk, A, Tidey, K, Ahmed, S, Tuttle, K, Vahdatihassani, F, Cholak, S, Cook, L, Steiner, T.S, Subramaniam, S. | 登録日 | 2024-01-09 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | SARS-CoV-2 XBB.1.5 Spike Protein: Altered Receptor Binding, Antibody Evasion, and Retention of T Cell Recognition To Be Published
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8AJL
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![BU of 8ajl by Molmil](/molmil-images/mine/8ajl) | Structure of the Ancestral Scaffold Antigen-6 of Coronavirus Spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin | 著者 | Hueting, D, Schriever, K, Wallden, K, Andrell, J, Syren, P.O. | 登録日 | 2022-07-28 | 公開日 | 2023-08-16 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Design, structure and plasma binding of ancestral beta-CoV scaffold antigens. Nat Commun, 14, 2023
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8XNK
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![BU of 8xnk by Molmil](/molmil-images/mine/8xnk) | Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | 著者 | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | 登録日 | 2023-12-30 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | 主引用文献 | Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published
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8IF2
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![BU of 8if2 by Molmil](/molmil-images/mine/8if2) | Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron BQ.1.1 variant spike protein in complex with its receptor ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Kimura, K, Suzuki, T, Hashiguchi, T. | 登録日 | 2023-02-17 | 公開日 | 2023-05-17 | 最終更新日 | 2023-05-24 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant. Nat Commun, 14, 2023
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7E7X
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![BU of 7e7x by Molmil](/molmil-images/mine/7e7x) | |
7L0N
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![BU of 7l0n by Molmil](/molmil-images/mine/7l0n) | Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Snell, G, Czudnochowski, N, Dillen, J, Nix, J.C, Croll, T.I, Corti, D. | 登録日 | 2020-12-11 | 公開日 | 2021-02-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity. Cell, 184, 2021
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8GOM
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![BU of 8gom by Molmil](/molmil-images/mine/8gom) | |
8XN2
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![BU of 8xn2 by Molmil](/molmil-images/mine/8xn2) | SARS-CoV-2 Omicron EG.5.1 RBD in complex with human ACE2 (local refined from the spike protein) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | 著者 | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | 登録日 | 2023-12-28 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published
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8JYM
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![BU of 8jym by Molmil](/molmil-images/mine/8jym) | Structure of the SARS-CoV-2 XBB.1.5 spike glycoprotein (closed state 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Sasaki, J, Sasaki-Tabata, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2023-07-03 | 公開日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Virological characteristics of the SARS-CoV-2 XBB.1.5 variant To Be Published
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8TM1
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![BU of 8tm1 by Molmil](/molmil-images/mine/8tm1) | |
7WPB
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![BU of 7wpb by Molmil](/molmil-images/mine/7wpb) | SARS-CoV-2 Omicron Variant RBD complexed with ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... | 著者 | Yin, W, Xu, Y, Xu, P, Cao, X, Wu, C, Gu, C, He, X, Wang, X, Huang, S, Yuan, Q, Wu, K, Hu, W, Huang, Z, Liu, J, Wang, Z, Jia, F, Xia, K, Liu, P, Wang, X, Song, B, Zheng, J, Jiang, H, Cheng, X, Jiang, Y, Deng, S, Xu, E. | 登録日 | 2022-01-23 | 公開日 | 2022-03-09 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody. Science, 375, 2022
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7T9J
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![BU of 7t9j by Molmil](/molmil-images/mine/7t9j) | Cryo-EM structure of the SARS-CoV-2 Omicron spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Tuttle, K.S, Subramaniam, S. | 登録日 | 2021-12-19 | 公開日 | 2021-12-29 | 最終更新日 | 2022-05-18 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein-ACE2 complex. Science, 375, 2022
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7SXY
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![BU of 7sxy by Molmil](/molmil-images/mine/7sxy) | Cryo-EM structure of the SARS-CoV-2 D614G mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Kim, A, Li, W, Dimitrov, D.S, Subramaniam, S. | 登録日 | 2021-11-24 | 公開日 | 2021-12-29 | 最終更新日 | 2022-01-05 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding. Cell Rep, 37, 2021
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7SXV
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![BU of 7sxv by Molmil](/molmil-images/mine/7sxv) | Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417N mutant spike protein ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Kim, A, Li, W, Dimitrov, D.S, Subramaniam, S. | 登録日 | 2021-11-24 | 公開日 | 2021-12-29 | 最終更新日 | 2022-01-05 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding. Cell Rep, 37, 2021
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8DMA
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![BU of 8dma by Molmil](/molmil-images/mine/8dma) | Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2 (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Cholak, S, Tuttle, K.S, Vahdatihassani, F, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep, 42, 2023
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7KFW
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![BU of 7kfw by Molmil](/molmil-images/mine/7kfw) | Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B3 Fab) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, heavy chain of antibody C1A-B3 Fab, ... | 著者 | Pan, J, Abraham, J, Clark, L, Clark, S. | 登録日 | 2020-10-15 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.792 Å) | 主引用文献 | Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2. Biorxiv, 2020
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7XTZ
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![BU of 7xtz by Molmil](/molmil-images/mine/7xtz) | Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-1 Conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | 著者 | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | 登録日 | 2022-05-18 | 公開日 | 2022-07-20 | 最終更新日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. Plos Pathog., 18, 2022
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7Y21
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![BU of 7y21 by Molmil](/molmil-images/mine/7y21) | S-ECD (Omicron BA.5) in complex with PD of ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Li, Y.N, Shen, Y.P, Zhang, Y.Y, Yan, R.H. | 登録日 | 2022-06-09 | 公開日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural Basis for the Enhanced Infectivity and Immune Evasion of Omicron Subvariants. Viruses, 15, 2023
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8EPN
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![BU of 8epn by Molmil](/molmil-images/mine/8epn) | |