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PDB: 260 件
2N8J
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Structure and 15N relaxation data of Calmodulin bound to the endothelial Nitric Oxide Synthase Calmodulin Binding Domain Peptide at Physiological Calcium Concentration
分子名称: Calmodulin, Nitric oxide synthase, endothelial
著者Piazza, M, Guillemette, G, Dieckmann, T.
登録日2015-10-16
公開日2016-10-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Studies of a Complex Between Endothelial Nitric Oxide Synthase and Calmodulin at Physiological Calcium Concentration.
Biochemistry, 55, 2016
2N27
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Competitive inhibition of TRPV1 calmodulin interaction by vanilloids
分子名称: (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, CALCIUM ION, Calmodulin
著者Hetenyi, A, Nemeth, L, Weber, E, Szakonyi, G, Winter, Z, Josvay, K, Bartus, E, Olah, Z, Martinek, T.A.
登録日2015-04-29
公開日2016-07-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Competitive inhibition of TRPV1-calmodulin interaction by vanilloids.
Febs Lett., 590, 2016
6ZBI
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Ternary complex of Calmodulin bound to 2 molecules of NHE1
分子名称: CALCIUM ION, Calmodulin-1, Sodium/hydrogen exchanger 1
著者Prestel, A, Kragelund, B.B, Pedersen, E.S, Pedersen, S.F, Sjoegaard-Frich, L.M.
登録日2020-06-08
公開日2021-03-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dynamic Na + /H + exchanger 1 (NHE1) - calmodulin complexes of varying stoichiometry and structure regulate Ca 2+ -dependent NHE1 activation.
Elife, 10, 2021
2KUG
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Halothane binds to druggable sites in calcium-calmodulin: Solution Structure of halothane-CaM N-terminal domain
分子名称: 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE, CALCIUM ION, Calmodulin-1
著者Juranic, N, Macura, S, Simeonov, M.V, Jones, K.A, Penheiter, A.R, Hock, T.J, Streiff, J.H.
登録日2010-02-17
公開日2010-03-09
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Halothane binds to druggable sites in the [Ca2+]4-calmodulin (CaM) complex, but does not inhibit [Ca2+]4-CaM activation of kinase.
J. Serb. Chem. Soc., 78, 2013
5OEO
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Solution structure of the complex of TRPV5(655-725) with a Calmodulin E32Q/E68Q double mutant
分子名称: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 5
著者Vuister, G.W, Bokhovchuk, F.M, Bate, N, Kovalevskaya, N, Goult, B.T, Spronk, C.A.E.M.
登録日2017-07-09
公開日2018-04-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Structural Basis of Calcium-Dependent Inactivation of the Transient Receptor Potential Vanilloid 5 Channel.
Biochemistry, 57, 2018
6FEG
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Solution Structure of CaM/Kv7.2-hAB Complex
分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2,Potassium voltage-gated channel subfamily KQT member 2
著者Bernardo-Seisdedos, G, Villarroel, A, Millet, O.
登録日2018-01-02
公開日2018-02-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis and energy landscape for the Ca2+gating and calmodulation of the Kv7.2 K+channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FEH
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Solution Structure of CaM/Kv7.2-hAB Complex
分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2,Potassium voltage-gated channel subfamily KQT member 2
著者Bernardo-Seisdedos, G, Villarroel, A, Millet, O.
登録日2018-01-02
公開日2018-02-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis and energy landscape for the Ca2+gating and calmodulation of the Kv7.2 K+channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5TP5
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Solution structure of the calcium deficient mutant calmodulin CaM1234
分子名称: Calmodulin
著者Piazza, M, Dieckmann, T, Guillemette, J.G.
登録日2016-10-19
公開日2017-09-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Consequences of Calmodulin EF Hand Mutations.
Biochemistry, 56, 2017
2K0J
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Solution structure of CaM complexed to DRP1p
分子名称: CALCIUM ION, LANTHANUM (III) ION, calmodulin
著者Bertini, I, Luchinat, C, Parigi, G, Yuan, J, Structural Proteomics in Europe (SPINE)
登録日2008-02-04
公開日2009-03-10
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Accurate solution structures of proteins from X-ray data and a minimal set of NMR data: calmodulin-peptide complexes as examples.
J.Am.Chem.Soc., 131, 2009
2KNE
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Calmodulin wraps around its binding domain in the plasma membrane CA2+ pump anchored by a novel 18-1 motif
分子名称: ATPase, Ca++ transporting, plasma membrane 4, ...
著者Juranic, N, Atanasova, E, Filoteo, A.G, Macura, S, Prendergast, F.G, Penniston, J.T, Strehler, E.E.
登録日2009-08-21
公開日2009-11-24
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Calmodulin wraps around its binding domain in the plasma membrane Ca2+ pump anchored by a novel 18-1 motif.
J.Biol.Chem., 285, 2010
6Y94
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Ca2+-bound Calmodulin mutant N53I
分子名称: CALCIUM ION, Calmodulin
著者Holt, C, Nielsen, L.H, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R.
登録日2020-03-06
公開日2020-04-29
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
8BFG
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Solution structure of human apo/Calmodulin G113R (G114R)
分子名称: Calmodulin-1
著者Wimmer, R, Holler, C.V, Petersson, N.M, Brohus, M.B, Niemelae, M, Overgaard, M.T, Iwai, H.
登録日2022-10-25
公開日2023-10-04
最終更新日2024-01-17
実験手法SOLUTION NMR
主引用文献Allosteric changes in protein stability and dynamics as pathogenic mechanism for calmodulin variants not affecting Ca 2+ coordinating residues.
Cell Calcium, 117, 2023
2HF5
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The structure and function of a novel two-site calcium-binding fragment of calmodulin
分子名称: CALCIUM ION, Calmodulin
著者Lakowski, T.M, Lee, G.M, Reid, R.E, McIntosh, L.P.
登録日2006-06-23
公開日2007-05-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Calcium-induced folding of a fragment of calmodulin composed of EF-hands 2 and 3
Protein Sci., 16, 2007
5GGM
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The NMR structure of calmodulin in CTAB reverse micelles
分子名称: CALCIUM ION, Calmodulin, TERBIUM(III) ION
著者Xu, G, Cheng, K, Wu, Q, Liu, M, Li, C.
登録日2016-06-16
公開日2016-09-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The NMR structure of calmodulin in CTAB reverse micelles
To Be Published
6BUT
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Solution structure of full-length apo mammalian calmodulin bound to the IQ motif of the human voltage-gated sodium channel NaV1.2
分子名称: Calmodulin-1, Sodium channel protein type 2 subunit alpha
著者Mahling, R, Kilpatrick, A.M, Shea, M.A.
登録日2017-12-11
公開日2019-06-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Na V 1.2 EFL domain allosterically enhances Ca 2+ binding to sites I and II of WT and pathogenic calmodulin mutants bound to the channel CTD.
Structure, 2021
2L7L
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Solution structure of Ca2+/calmodulin complexed with a peptide representing the calmodulin-binding domain of calmodulin kinase I
分子名称: CALCIUM ION, Calcium/calmodulin-dependent protein kinase type 1, Calmodulin
著者Gifford, J.L, Ishida, H, Vogel, H.J.
登録日2010-12-13
公開日2011-05-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Fast methionine-based solution structure determination of calcium-calmodulin complexes.
J.Biomol.Nmr, 50, 2011
6GDL
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Calmodulin mutant - F141L apo-form Unstructured C-domain
分子名称: Calmodulin-1
著者Holt, C, Overgaard, M.T, Wimmer, R.
登録日2018-04-23
公開日2018-10-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7L8V
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NMR Structure of half-calcified calmodulin mutant (CaMEF12) bound to the IQ-motif of CaV1.2
分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Ames, J.B.
登録日2021-01-01
公開日2022-07-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Half-calcified calmodulin promotes basal activity and inactivation of the L-type calcium channel Ca V 1.2.
J.Biol.Chem., 298, 2022
1SW8
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Solution structure of the N-terminal domain of Human N60D calmodulin refined with paramagnetism based strategy
分子名称: CALCIUM ION, Calmodulin
著者Bertini, I, Del Bianco, C, Gelis, I, Katsaros, N, Luchinat, C, Parigi, G, Peana, M, Provenzani, A, Zoroddu, M.A, Structural Proteomics in Europe (SPINE)
登録日2004-03-30
公開日2004-04-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Experimentally exploring the conformational space sampled by domain reorientation in calmodulin
Proc.Natl.Acad.Sci.USA, 101, 2004
2LL6
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Solution NMR structure of CaM bound to iNOS CaM binding domain peptide
分子名称: Calmodulin, Nitric oxide synthase, inducible
著者Piazza, M, Futrega, K, Spratt, D.E, Dieckmann, T, Guillemette, J.G.
登録日2011-10-29
公開日2012-05-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and Dynamics of Calmodulin (CaM) Bound to Nitric Oxide Synthase Peptides: Effects of a Phosphomimetic CaM Mutation.
Biochemistry, 51, 2012
2K0E
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A Coupled Equilibrium Shift Mechanism in Calmodulin-Mediated Signal Transduction
分子名称: CALCIUM ION, Calmodulin
著者Gsponer, J, Christodoulou, J, Cavalli, A, Bui, J.M, Richter, B, Dobson, C.M, Vendruscolo, M.
登録日2008-02-02
公開日2008-06-10
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction
Structure, 16, 2008
2JZI
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Structure of Calmodulin complexed with the Calmodulin Binding Domain of Calcineurin
分子名称: CALCIUM ION, Calmodulin, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
著者Chyan, C, Huang, J, Irene, D, Lin, T.
登録日2008-01-09
公開日2009-01-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of Calmodulin complexed with the Calmodulin Binding Domain of Calcineurin
To be Published
6GDK
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Calcium bound form of human calmodulin mutant F141L
分子名称: CALCIUM ION, Calmodulin-1
著者Grachov, O, Holt, C, Overgaard, M.T, Wimmer, R.
登録日2018-04-23
公開日2018-10-17
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2LL7
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Solution NMR structure of CaM bound to the eNOS CaM binding domain peptide
分子名称: Calmodulin, Nitric oxide synthase, endothelial
著者Piazza, M, Futrega, K, Spratt, D.E, Guillemette, J.G, Dieckmann, T.
登録日2011-10-29
公開日2012-05-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and Dynamics of Calmodulin (CaM) Bound to Nitric Oxide Synthase Peptides: Effects of a Phosphomimetic CaM Mutation.
Biochemistry, 51, 2012
1NKF
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CALCIUM-BINDING PEPTIDE, NMR, 30 STRUCTURES
分子名称: CALCIUM-BINDING HEXADECAPEPTIDE, LANTHANUM (III) ION
著者Sticht, H, Ejchart, A.
登録日1998-03-09
公開日1999-02-16
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Alpha-helix nucleation by a calcium-binding peptide loop.
Proc.Natl.Acad.Sci.USA, 96, 1999

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