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PDB: 21 件
6XZ2
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Crystal structure of E. Coli purine nucleoside phosphorylase mutant Y160W with SO4 and Formycin A
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, Purine nucleoside phosphorylase DeoD-type, SULFATE ION
著者Narczyk, M, Bzowska, A.
登録日2020-01-31
公開日2021-02-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65000308 Å)
主引用文献Single tryptophan Y160W mutant of homooligomeric E. coli purine nucleoside phosphorylase implies that dimers forming the hexamer are functionally not equivalent.
Sci Rep, 11, 2021
4TS9
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Crystal structure of wild type E. Coli purine nucleoside phosphorylase with 6 FMC molecules
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
著者Stefanic, Z, Bzowska, A.
登録日2014-06-18
公開日2015-07-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis.
Sci Rep, 8, 2018
4TTJ
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Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 6 FMC molecules
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type, ...
著者Stefanic, Z, Bzowska, A.
登録日2014-06-21
公開日2015-07-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.874 Å)
主引用文献Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis.
Sci Rep, 8, 2018
4TTI
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Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 4 FMC molecules
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type, ...
著者Stefanic, Z, Bzowska, A.
登録日2014-06-21
公開日2015-07-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis.
Sci Rep, 8, 2018
3ONV
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BU of 3onv by Molmil
Crystal structure of E. Coli purine nucleoside phosphorylase with SO4
分子名称: Purine nucleoside phosphorylase deoD-type, SULFATE ION
著者Mikleusevic, G, Stefanic, Z, Narzyk, M, Wielgus-Kutrowska, B, Bzowska, A, Luic, M.
登録日2010-08-30
公開日2011-07-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.893 Å)
主引用文献Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies.
Biochimie, 93, 2011
3UT6
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Crystal structure of E. Coli PNP complexed with PO4 and formycin A
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type
著者Stefanic, Z.
登録日2011-11-25
公開日2012-05-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A.
Febs Lett., 586, 2012
1ECP
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PURINE NUCLEOSIDE PHOSPHORYLASE
分子名称: PURINE NUCLEOSIDE PHOSPHORYLASE
著者Mao, C, Ealick, S.E.
登録日1995-07-13
公開日1996-06-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology.
Structure, 5, 1997
3OOE
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Crystal structure of E. Coli purine nucleoside phosphorylase with PO4
分子名称: PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type
著者Mikleusevic, G, Stefanic, Z, Narzyk, M, Wielgus-Kutrowska, B, Bzowska, A, Luic, M.
登録日2010-08-31
公開日2011-07-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies.
Biochimie, 93, 2011
4TTA
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Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 2 FMC molecules
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type, ...
著者Stefanic, Z, Bzowska, A.
登録日2014-06-20
公開日2015-07-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis.
Sci Rep, 8, 2018
1K9S
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PURINE NUCLEOSIDE PHOSPHORYLASE FROM E. COLI IN COMPLEX WITH FORMYCIN A DERIVATIVE AND PHOSPHATE
分子名称: 2-(7-AMINO-6-METHYL-3H-PYRAZOLO[4,3-D]PYRIMIDIN-3-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, 2-HYDROXYMETHYL-5-(7-METHYLAMINO-3H-PYRAZOLO[4,3-D]PYRIMIDIN-3-YL)-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, ...
著者Koellner, G, Bzowska, A, Wielgus-Kutrowska, B, Luic, M, Steiner, T, Saenger, W, Stepinski, J.
登録日2001-10-30
公開日2001-11-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism.
J.Mol.Biol., 315, 2002
1A69
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PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLEX WITH FORMYCIN B AND SULPHATE (PHOSPHATE)
分子名称: FORMYCIN B, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION
著者Koellner, G, Luic, M, Shugar, D, Saenger, W, Bzowska, A.
登録日1998-03-08
公開日1998-10-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the ternary complex of E. coli purine nucleoside phosphorylase with formycin B, a structural analogue of the substrate inosine, and phosphate (Sulphate) at 2.1 A resolution.
J.Mol.Biol., 280, 1998
1OVG
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M64V PNP +MePdr
分子名称: 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-26
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
4TS3
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Wild type E. Coli purine nucleoside phosphorylase with 2 FMC molecules in active sites
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
著者Stefanic, Z, Bzowska, A.
登録日2014-06-18
公開日2015-07-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis.
Sci Rep, 8, 2018
1OV6
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M64V PNP + ALLO
分子名称: 9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-25
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
3OPV
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Crystal structure of E. Coli purine nucleoside phosphorylase Arg24Ala mutant
分子名称: PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type
著者Mikleusevic, G, Stefanic, Z, Narzyk, M, Wielgus-Kutrowska, B, Bzowska, A, Luic, M.
登録日2010-09-02
公開日2011-07-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies.
Biochimie, 93, 2011
1OUM
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M64V PNP +Talo
分子名称: 9-(6-DEOXY-ALPHA-L-TALOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-24
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OU4
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Native PNP +Talo
分子名称: 6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-24
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OTY
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Native PNP +ALLO
分子名称: 6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-23
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
5IU6
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Crystal structure of E.coli purine nucleoside phosphorylase with 7-deazahypoxanthine
分子名称: 7H-pyrrolo[2,3-d]pyrimidin-4-ol, Purine nucleoside phosphorylase DeoD-type, SULFATE ION
著者Timofeev, V.I, Abramchik, Y.A, Esipov, R.S, Kuranova, I.P.
登録日2016-03-17
公開日2017-04-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Crystal structure of Escherichia coli purine nucleoside phosphorylase in complex with 7-deazahypoxanthine.
Acta Crystallogr F Struct Biol Commun, 74, 2018
1OTX
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Purine Nucleoside Phosphorylase M64V mutant
分子名称: PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-23
公開日2004-02-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
3OOH
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Crystal structure of E. Coli purine nucleoside phosphorylase with PO4
分子名称: PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type
著者Mikleusevic, G, Stefanic, Z, Narzyk, M, Wielgus-Kutrowska, B, Bzowska, A, Luic, M.
登録日2010-08-31
公開日2011-07-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies.
Biochimie, 93, 2011

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