3LTI
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![BU of 3lti by Molmil](/molmil-images/mine/3lti) | |
7EGS
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![BU of 7egs by Molmil](/molmil-images/mine/7egs) | The crystal structure of lobe domain of E. coli RNA polymerase complexed with the C-terminal domain of UvrD | 分子名称: | DNA helicase II, DNA-directed RNA polymerase subunit beta, GLYCEROL | 著者 | Zheng, F, Shen, L, Li, L, Zhang, Y. | 登録日 | 2021-03-26 | 公開日 | 2022-04-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crucial role and mechanism of transcription-coupled DNA repair in bacteria. Nature, 604, 2022
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8FVW
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![BU of 8fvw by Molmil](/molmil-images/mine/8fvw) | |
8FVR
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![BU of 8fvr by Molmil](/molmil-images/mine/8fvr) | |
8HKC
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![BU of 8hkc by Molmil](/molmil-images/mine/8hkc) | Cryo-EM structure of E. coli RNAP sigma32 complex | 分子名称: | DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Wu, S, Ma, L.X. | 登録日 | 2022-11-25 | 公開日 | 2023-05-31 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | 主引用文献 | Structural Insight into the Mechanism of sigma 32-Mediated Transcription Initiation of Bacterial RNA Polymerase. Biomolecules, 13, 2023
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6XL9
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![BU of 6xl9 by Molmil](/molmil-images/mine/6xl9) | Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 3-nt RNA transcript (EcmrR-RPitc-3nt) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Yang, Y, Liu, C, Shi, W, Liu, B. | 登録日 | 2020-06-28 | 公開日 | 2021-04-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
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6XL5
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![BU of 6xl5 by Molmil](/molmil-images/mine/6xl5) | Cryo-EM structure of EcmrR-RNAP-promoter open complex (EcmrR-RPo) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Yang, Y, Liu, C, Liu, B. | 登録日 | 2020-06-28 | 公開日 | 2021-04-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
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8F1J
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![BU of 8f1j by Molmil](/molmil-images/mine/8f1j) | SigN RNA polymerase early-melted intermediate bound to mismatch DNA fragment dhsU36mm2 (-12A) | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Mueller, A.U, Chen, J, Darst, S.A. | 登録日 | 2022-11-05 | 公開日 | 2023-04-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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8PIB
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![BU of 8pib by Molmil](/molmil-images/mine/8pib) | autoinhibited RfaH bound to E. coli transcription complex paused at ops site (encounter complex) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | 登録日 | 2023-06-21 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8SY7
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![BU of 8sy7 by Molmil](/molmil-images/mine/8sy7) | E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-STP base pair in the active site | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Shan, Z, Lyumkis, D, Oh, J, Wang, D. | 登録日 | 2023-05-24 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase. Nat Commun, 14, 2023
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8SY5
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![BU of 8sy5 by Molmil](/molmil-images/mine/8sy5) | E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dS-BTP base pair in the active site | 分子名称: | 2-oxo-2-hydroadenosine 5'-(tetrahydrogen triphosphate), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Shan, Z, Lyumkis, D, Oh, J, Wang, D. | 登録日 | 2023-05-24 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase. Nat Commun, 14, 2023
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6XLJ
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![BU of 6xlj by Molmil](/molmil-images/mine/6xlj) | Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 4-nt RNA transcript (EcmrR-RPitc-4nt) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Yang, Y, Liu, C, Liu, B. | 登録日 | 2020-06-28 | 公開日 | 2021-04-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
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6XLL
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![BU of 6xll by Molmil](/molmil-images/mine/6xll) | Cryo-EM structure of E. coli RNAP-promoter initial transcribing complex with 5-nt RNA transcript (RPitc-5nt) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Yang, Y, Liu, C, Liu, B. | 登録日 | 2020-06-28 | 公開日 | 2021-04-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
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8JO2
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![BU of 8jo2 by Molmil](/molmil-images/mine/8jo2) | Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA | 分子名称: | DNA (65-MER), DNA-binding transcriptional regulator BasR, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lou, Y.-C, Huang, H.-Y, Chen, C, Wu, K.-P. | 登録日 | 2023-06-06 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA. Nucleic Acids Res., 51, 2023
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8FTD
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![BU of 8ftd by Molmil](/molmil-images/mine/8ftd) | Structure of Escherichia coli CedA in complex with transcription initiation complex | 分子名称: | CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Liu, M, Vassyliev, N, Nudler, E. | 登録日 | 2023-01-11 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | General transcription factor from Escherichia coli with a distinct mechanism of action. Nat.Struct.Mol.Biol., 31, 2024
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8F1K
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![BU of 8f1k by Molmil](/molmil-images/mine/8f1k) | SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T) | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Mueller, A.U, Chen, J, Darst, S.A. | 登録日 | 2022-11-05 | 公開日 | 2023-04-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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8PDY
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![BU of 8pdy by Molmil](/molmil-images/mine/8pdy) | E. coli RNA polymerase paused at ops site | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | 登録日 | 2023-06-13 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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6XLN
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![BU of 6xln by Molmil](/molmil-images/mine/6xln) | Cryo-EM structure of E. coli RNAP-DNA elongation complex 2 (RDe2) in EcmrR-dependent transcription | 分子名称: | 9-nt RNA transcript, CHAPSO, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Yang, Y, Liu, C, Liu, B. | 登録日 | 2020-06-28 | 公開日 | 2021-04-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
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8TO1
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![BU of 8to1 by Molmil](/molmil-images/mine/8to1) | Escherichia coli RNA polymerase unwinding intermediate (I1a) at the lambda PR promoter | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Darst, S.A, Saecker, R.M, Mueller, A.U. | 登録日 | 2023-08-02 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024
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8RE4
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8PBL
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7MKJ
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![BU of 7mkj by Molmil](/molmil-images/mine/7mkj) | Cryo-EM structure of Escherichia coli RNA polymerase bound to T7A1 promoter DNA | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | 登録日 | 2021-04-23 | 公開日 | 2021-09-29 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
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8TO8
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![BU of 8to8 by Molmil](/molmil-images/mine/8to8) | Escherichia coli RNA polymerase unwinding intermediate (I1b) at the lambda PR promoter | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Darst, S.A, Saecker, R.M, Mueller, A.U. | 登録日 | 2023-08-03 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024
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8TOE
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8TO6
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![BU of 8to6 by Molmil](/molmil-images/mine/8to6) | Escherichia coli RNA polymerase unwinding intermediate (I1d) at the lambda PR promoter | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Darst, S.A, Saecker, R.M, Mueller, A.U. | 登録日 | 2023-08-02 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024
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