6X4Y
 
 | | Mfd-bound E.coli RNA polymerase elongation complex - IV state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | | 登録日 | 2020-05-24 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
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6X43
 | | Mfd-bound E.coli RNA polymerase elongation complex - II state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | | 登録日 | 2020-05-22 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
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6GOV
 | | Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX | | 分子名称: | 30S ribosomal protein S10, Antitermination protein N, DNA (I), ... | | 著者 | Loll, B, Krupp, F, Said, N, Huang, Y, Buerger, J, Mielke, T, Spahn, C.M.T, Wahl, M.C. | | 登録日 | 2018-06-04 | | 公開日 | 2019-02-13 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor.
Mol.Cell, 74, 2019
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7MKE
 | | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | | 登録日 | 2021-04-23 | | 公開日 | 2021-09-29 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8EHA
 | | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (out) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | | 登録日 | 2022-09-14 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
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6PSW
 | | Escherichia coli RNA polymerase promoter unwinding intermediate (TRPo) with TraR and rpsT P2 promoter | | 分子名称: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | | 登録日 | 2019-07-13 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
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6XDQ
 | | Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 30 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | 著者 | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | | 登録日 | 2020-06-11 | | 公開日 | 2020-09-02 | | 最終更新日 | 2020-09-23 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis of transcription-translation coupling.
Science, 369, 2020
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4YG2
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7N4E
 | | Escherichia coli sigma 70-dependent paused transcription elongation complex | | 分子名称: | 5'-R(*UP*UP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3', DNA (61-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Molodtsov, V, Su, M, Ebright, R.H. | | 登録日 | 2021-06-04 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural and mechanistic basis of sigma-dependent transcriptional pausing.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8EGB
 | | Cryo-EM structure of consensus elemental paused elongation complex with an unfolded TL | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | | 登録日 | 2022-09-12 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
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6X4W
 | | Mfd-bound E.coli RNA polymerase elongation complex - III state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | | 登録日 | 2020-05-24 | | 公開日 | 2021-02-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
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6N62
 | | Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. | | 登録日 | 2018-11-24 | | 公開日 | 2019-01-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.803 Å) | | 主引用文献 | Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6PSU
 | | Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi2) with TraR and rpsT P2 promoter | | 分子名称: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | | 登録日 | 2019-07-13 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
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8EH9
 | | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (2) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | | 登録日 | 2022-09-13 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
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6X2N
 | | Mfd-bound E.coli RNA polymerase elongation complex - I state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | | 登録日 | 2020-05-20 | | 公開日 | 2021-02-03 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
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6X2F
 | | Mfd-bound E.coli RNA polymerase elongation complex - L2 state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | | 登録日 | 2020-05-20 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
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6VJS
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6P1K
 | | Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | | 登録日 | 2019-05-20 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | | 主引用文献 | E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation.
Elife, 8, 2019
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6X26
 | | Mfd-bound E.coli RNA polymerase elongation complex - L1 state | | 分子名称: | DNA (64-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | | 登録日 | 2020-05-20 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
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8E6Z
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, dC75 rut mimic RNA, Mg-ADP-BeF3, and NusG; TEC part | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | | 登録日 | 2022-08-23 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
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8E5K
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 21 nt long RNA spacer, Mg-ADP-BeF3, and NusG; TEC part | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Molodtsov, V, Wang, C. | | 登録日 | 2022-08-22 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
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8E6X
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, lambda-tR1 rut RNA, Mg-ADP-BeF3, and NusG; TEC part | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Molodtsov, V, Wang, C. | | 登録日 | 2022-08-23 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
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8E5O
 | | Escherichia coli Rho-dependent transcription pre-termination complex containing 24 nt long RNA spacer, Mg-ADP-BeF3, and NusG; TEC part | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Molodtsov, V, Wang, C. | | 登録日 | 2022-08-22 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
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6XDR
 | | Escherichia coli transcription-translation complex B (TTC-B) containing an 27 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | | 登録日 | 2020-06-11 | | 公開日 | 2020-09-02 | | 最終更新日 | 2020-09-23 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structural basis of transcription-translation coupling.
Science, 369, 2020
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6X9Q
 | | Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 27 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | 著者 | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | | 登録日 | 2020-06-03 | | 公開日 | 2020-09-02 | | 最終更新日 | 2020-09-23 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structural basis of transcription-translation coupling.
Science, 369, 2020
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