6XH8
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![BU of 6xh8 by Molmil](/molmil-images/mine/6xh8) | CueR-transcription activation complex with RNA transcript | 分子名称: | COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Liu, B, Shi, W, Yang, Y. | 登録日 | 2020-06-18 | 公開日 | 2021-04-14 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of copper-efflux-regulator-dependent transcription activation. Iscience, 24, 2021
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8AC0
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8AD1
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5UAH
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![BU of 5uah by Molmil](/molmil-images/mine/5uah) | Escherichia coli RNA polymerase and Rifampin complex, RpoB D516V mutant | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Molodtsov, V, Scharf, N.T, Stefan, M.A, Garcia, G.A, Murakami, K.S. | 登録日 | 2016-12-19 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis. Mol. Microbiol., 103, 2017
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7PYK
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![BU of 7pyk by Molmil](/molmil-images/mine/7pyk) | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in more-swiveled conformation) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | 登録日 | 2021-10-10 | 公開日 | 2022-03-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY7
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![BU of 7py7 by Molmil](/molmil-images/mine/7py7) | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in more-swiveled conformation) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | 登録日 | 2021-10-09 | 公開日 | 2022-03-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY6
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![BU of 7py6 by Molmil](/molmil-images/mine/7py6) | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in less-swiveled conformation) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | 登録日 | 2021-10-09 | 公開日 | 2022-03-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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8E6Z
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![BU of 8e6z by Molmil](/molmil-images/mine/8e6z) | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, dC75 rut mimic RNA, Mg-ADP-BeF3, and NusG; TEC part | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2022-08-23 | 公開日 | 2022-09-07 | 最終更新日 | 2023-02-22 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of Rho-dependent transcription termination. Nature, 614, 2023
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6FLP
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6Z9T
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![BU of 6z9t by Molmil](/molmil-images/mine/6z9t) | Transcription termination intermediate complex 5 | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Said, N, Hilal, T, Loll, B, Wahl, M.C. | 登録日 | 2020-06-04 | 公開日 | 2020-11-04 | 最終更新日 | 2021-02-03 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho. Science, 371, 2021
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6GH6
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![BU of 6gh6 by Molmil](/molmil-images/mine/6gh6) | Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme intermediate partially loaded complex | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Glyde, R, Ye, F.Z, Zhang, X.D. | 登録日 | 2018-05-04 | 公開日 | 2018-07-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation. Mol. Cell, 70, 2018
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6CUX
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7KHC
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![BU of 7khc by Molmil](/molmil-images/mine/7khc) | Escherichia coli RNA polymerase and rrnBP1 promoter closed complex | 分子名称: | CHAPSO, DNA (18 MER), DNA (63-MER), ... | 著者 | Shin, Y, Qayyum, M.Z, Murakami, K.S. | 登録日 | 2020-10-20 | 公開日 | 2020-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | 主引用文献 | Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
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6UTY
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![BU of 6uty by Molmil](/molmil-images/mine/6uty) | E. coli sigma-S transcription initiation complex with a mismatching CTP ("Old" crystal soaked with CTP for 30 minutes) | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.15 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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5IPM
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![BU of 5ipm by Molmil](/molmil-images/mine/5ipm) | SigmaS-transcription initiation complex with 4-nt nascent RNA | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Liu, B, Zuo, Y, Steitz, T.A. | 登録日 | 2016-03-09 | 公開日 | 2016-03-30 | 最終更新日 | 2016-06-22 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
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7W5Y
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8E5K
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![BU of 8e5k by Molmil](/molmil-images/mine/8e5k) | Escherichia coli Rho-dependent transcription pre-termination complex containing 21 nt long RNA spacer, Mg-ADP-BeF3, and NusG; TEC part | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Molodtsov, V, Wang, C. | 登録日 | 2022-08-22 | 公開日 | 2022-09-07 | 最終更新日 | 2023-02-22 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural basis of Rho-dependent transcription termination. Nature, 614, 2023
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7PYJ
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![BU of 7pyj by Molmil](/molmil-images/mine/7pyj) | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in less-swiveled conformation) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | 登録日 | 2021-10-10 | 公開日 | 2022-03-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7ADE
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![BU of 7ade by Molmil](/molmil-images/mine/7ade) | Transcription termination complex IVa | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Said, N, Hilal, T, Loll, B, Wahl, C.M. | 登録日 | 2020-09-14 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho. Science, 371, 2021
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7BEG
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![BU of 7beg by Molmil](/molmil-images/mine/7beg) | Structures of class I bacterial transcription complexes | 分子名称: | Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Ye, F.Z, Hao, M, Zhang, X.D. | 登録日 | 2020-12-23 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation. Adv Sci, 9, 2022
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6UU6
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![BU of 6uu6 by Molmil](/molmil-images/mine/6uu6) | E. coli sigma-S transcription initiation complex with a 4-nt RNA and a UTP ("Old" crystal soaked with UTP, ddCTP, and dinucleotide ApG for 30 minutes) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.201 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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4JK2
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4ZH2
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![BU of 4zh2 by Molmil](/molmil-images/mine/4zh2) | |
7C17
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6C9Y
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![BU of 6c9y by Molmil](/molmil-images/mine/6c9y) | Cryo-EM structure of E. coli RNAP sigma70 holoenzyme | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yenool, D, Jiang, W, Murakami, K.S. | 登録日 | 2018-01-29 | 公開日 | 2018-02-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | 主引用文献 | Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation. J. Biol. Chem., 293, 2018
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