6GH6

Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme intermediate partially loaded complex

Summary for 6GH6

Entry DOI	10.2210/pdb6gh6/pdb
EMDB information	0002 4397
Descriptor	DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (7 entities in total)
Functional Keywords	transcription initiation, dna loading, transcription bubble, sigma factor, transcription
Biological source	Escherichia coli (strain K12) More
Total number of polymer chains	8
Total formula weight	483181.50
Authors	Glyde, R.,Ye, F.Z.,Zhang, X.D. (deposition date: 2018-05-04, release date: 2018-07-04, Last modification date: 2019-12-11)
Primary citation	Glyde, R.,Ye, F.,Jovanovic, M.,Kotta-Loizou, I.,Buck, M.,Zhang, X. Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation. Mol. Cell, 70:1111-1120.e3, 2018 Cited by PubMed: 29932903 DOI: 10.1016/j.molcel.2018.05.021 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.1 Å)

Structure validation