6XDQ
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![BU of 6xdq by Molmil](/molmil-images/mine/6xdq) | Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 30 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | 登録日 | 2020-06-11 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
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6R9G
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6N57
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![BU of 6n57 by Molmil](/molmil-images/mine/6n57) | Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation I | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-21 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
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6GOV
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![BU of 6gov by Molmil](/molmil-images/mine/6gov) | Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX | 分子名称: | 30S ribosomal protein S10, Antitermination protein N, DNA (I), ... | 著者 | Loll, B, Krupp, F, Said, N, Huang, Y, Buerger, J, Mielke, T, Spahn, C.M.T, Wahl, M.C. | 登録日 | 2018-06-04 | 公開日 | 2019-02-13 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor. Mol.Cell, 74, 2019
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6GFW
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![BU of 6gfw by Molmil](/molmil-images/mine/6gfw) | Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme initial transcribing complex | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Glyde, R, Ye, F.Z, Zhang, X.D. | 登録日 | 2018-05-02 | 公開日 | 2018-07-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation. Mol. Cell, 70, 2018
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5UI8
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![BU of 5ui8 by Molmil](/molmil-images/mine/5ui8) | structure of sigmaN-holoenzyme | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Darst, S.A, Campbell, E.A. | 登録日 | 2017-01-13 | 公開日 | 2017-02-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.76 Å) | 主引用文献 | Crystal structure of Aquifex aeolicus sigma (N) bound to promoter DNA and the structure of sigma (N)-holoenzyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5NWT
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![BU of 5nwt by Molmil](/molmil-images/mine/5nwt) | Crystal Structure of Escherichia coli RNA polymerase - Sigma54 Holoenzyme complex | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zhang, X, Buck, M, Darbari, V.C, Yang, Y, Zhang, N, Lu, D, Glyde, R, Wang, Y, Winkelman, J, Gourse, R.L, Murakami, K.S. | 登録日 | 2017-05-08 | 公開日 | 2017-09-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.76 Å) | 主引用文献 | TRANSCRIPTION. Structures of the RNA polymerase-Sigma54 reveal new and conserved regulatory strategies. Science, 349, 2015
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6N58
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![BU of 6n58 by Molmil](/molmil-images/mine/6n58) | Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation II | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-21 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
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5VT0
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6K4Y
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![BU of 6k4y by Molmil](/molmil-images/mine/6k4y) | CryoEM structure of sigma appropriation complex | 分子名称: | 10 kDa anti-sigma factor, DNA (60-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Shi, J, Wen, A, Feng, Y. | 登録日 | 2019-05-27 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | 主引用文献 | Structural basis of sigma appropriation. Nucleic Acids Res., 47, 2019
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6TQO
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![BU of 6tqo by Molmil](/molmil-images/mine/6tqo) | rrn anti-termination complex | 分子名称: | 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | 登録日 | 2019-12-17 | 公開日 | 2020-08-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
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6TQN
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![BU of 6tqn by Molmil](/molmil-images/mine/6tqn) | rrn anti-termination complex without S4 | 分子名称: | 30S ribosomal protein S10, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | 登録日 | 2019-12-17 | 公開日 | 2020-08-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
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6XAS
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![BU of 6xas by Molmil](/molmil-images/mine/6xas) | CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex | 分子名称: | DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Hao, Z.T, Kim, H.K, Walz, T, Nudler, E. | 登録日 | 2020-06-04 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Pre-termination Transcription Complex: Structure and Function. Mol.Cell, 81, 2021
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8REE
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![BU of 8ree by Molmil](/molmil-images/mine/8ree) | |
6P19
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8G4W
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![BU of 8g4w by Molmil](/molmil-images/mine/8g4w) | Cryo-EM consensus structure of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand | 分子名称: | 7-DEAZA-7-AMINOMETHYL-GUANINE, DNA (31-MER), DNA (39-mer), ... | 著者 | Porta, J.C, Chauvier, A, Deb, I, Ellinger, E, Frank, A.T, Meze, K, Ohi, M.D, Walter, N.G. | 登録日 | 2023-02-10 | 公開日 | 2023-06-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand. Nat.Struct.Mol.Biol., 30, 2023
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6ASX
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![BU of 6asx by Molmil](/molmil-images/mine/6asx) | CryoEM structure of E.coli his pause elongation complex | 分子名称: | DNA (32-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Landick, R, Darst, S.A. | 登録日 | 2017-08-25 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing. Mol. Cell, 69, 2018
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5UAC
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![BU of 5uac by Molmil](/molmil-images/mine/5uac) | Escherichia coli RNA polymerase and Rifampin complex, wild-type | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Molodtsov, V, Scharf, N.T, Stefan, M.A, Garcia, G.A, Murakami, K.S. | 登録日 | 2016-12-19 | 公開日 | 2017-01-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis. Mol. Microbiol., 103, 2017
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7PY8
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![BU of 7py8 by Molmil](/molmil-images/mine/7py8) | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (NusG-EC in less-swiveled conformation) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | 登録日 | 2021-10-09 | 公開日 | 2022-03-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY3
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![BU of 7py3 by Molmil](/molmil-images/mine/7py3) | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (the consensus NusA-EC) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | 登録日 | 2021-10-08 | 公開日 | 2022-03-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY1
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![BU of 7py1 by Molmil](/molmil-images/mine/7py1) | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (the consensus NusG-EC) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | 登録日 | 2021-10-08 | 公開日 | 2022-03-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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8UQP
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![BU of 8uqp by Molmil](/molmil-images/mine/8uqp) | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2023-10-24 | 公開日 | 2024-05-29 | 最終更新日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of RfaH-mediated transcription-translation coupling. Nat.Struct.Mol.Biol., 2024
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6R9B
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8EGB
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![BU of 8egb by Molmil](/molmil-images/mine/8egb) | Cryo-EM structure of consensus elemental paused elongation complex with an unfolded TL | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-12 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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7N4E
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![BU of 7n4e by Molmil](/molmil-images/mine/7n4e) | Escherichia coli sigma 70-dependent paused transcription elongation complex | 分子名称: | 5'-R(*UP*UP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3', DNA (61-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Molodtsov, V, Su, M, Ebright, R.H. | 登録日 | 2021-06-04 | 公開日 | 2022-06-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural and mechanistic basis of sigma-dependent transcriptional pausing. Proc.Natl.Acad.Sci.USA, 119, 2022
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