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PDB: 283 件

6UUB
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BU of 6uub by Molmil
E. coli sigma-S transcription initiation complex with a mismatching UTP ("Fresh" crystal soaked with UTP for 2 hours)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.955 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
4KN4
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BU of 4kn4 by Molmil
X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Benzoxazinorifamycin-2b
分子名称: Benzoxazinorifamycin-2b, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Murakami, K.S.
登録日2013-05-08
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.965 Å)
主引用文献X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins.
J.Med.Chem., 56, 2013
8Y6U
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BU of 8y6u by Molmil
Cryo-EM structure of E.coli transcription initiation complex with transcription factor GcvA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Lin, W, Shi, J.
登録日2024-02-03
公開日2024-06-05
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献NMR analysis of a loop-bulge structure of UUCGA pentaloop.
Biochem.Biophys.Res.Commun., 691, 2024
4ZH4
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BU of 4zh4 by Molmil
Crystal structure of Escherichia coli RNA polymerase in complex with CBRP18
分子名称: 5-(4-fluorophenyl)-4-[4-fluoro-3-(trifluoromethyl)phenyl]-1H-pyrazole, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Feng, Y, Ebright, R.H.
登録日2015-04-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.993 Å)
主引用文献Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Structure, 23, 2015
7Q0K
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BU of 7q0k by Molmil
RNA polymerase elongation complex in less-swiveled conformation
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhu, C, Guo, X, Weixlbaumer, A.
登録日2021-10-15
公開日2022-03-23
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7VWZ
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BU of 7vwz by Molmil
Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Lin, W, Feng, Y, Shi, J.
登録日2021-11-12
公開日2022-06-08
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Nucleic Acids Res., 50, 2022
6X2F
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BU of 6x2f by Molmil
Mfd-bound E.coli RNA polymerase elongation complex - L2 state
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A.
登録日2020-05-20
公開日2021-02-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
7ADC
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BU of 7adc by Molmil
Transcription termination intermediate complex 3 delta NusG
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ...
著者Said, N, Hilal, T, Loll, B, Wahl, C.M.
登録日2020-09-14
公開日2020-11-25
最終更新日2021-02-03
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
6UUA
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BU of 6uua by Molmil
E. coli sigma-S transcription initiation complex with a mismatching CTP ("Fresh" crystal soaked with CTP for 2 hours)
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.002 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UU3
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BU of 6uu3 by Molmil
E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Old" crystal soaked with GTP, ATP, CTP, and ddTTP for 30 minutes)
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.002 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6JBQ
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BU of 6jbq by Molmil
CryoEM structure of Escherichia coli sigmaE transcription initiation complex containing 5nt of RNA
分子名称: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Fang, C.L, Zhang, Y.
登録日2019-01-26
公開日2019-05-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
6VJS
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BU of 6vjs by Molmil
Escherichia coli RNA polymerase and ureidothiophene-2-carboxylic acid complex
分子名称: 3-{[benzyl(ethyl)carbamoyl]amino}-5-(4-phenoxyphenyl)thiophene-2-carboxylic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Murakami, K.S, Molodtsov, V.
登録日2020-01-17
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.02 Å)
主引用文献Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus -Based Wound Infection Model in SKH1 Mice.
Acs Infect Dis., 6, 2020
6UTX
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BU of 6utx by Molmil
E. coli sigma-S transcription initiation complex with an empty bubble ("Old" crystal)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.05 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6P1K
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BU of 6p1k by Molmil
Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
登録日2019-05-20
公開日2020-02-26
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation.
Elife, 8, 2019
8AC1
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BU of 8ac1 by Molmil
RNA polymerase at U-rich pause bound to non-regulatory RNA - inactive, open clamp state
分子名称: DNA Non-template strand, DNA Template strand, DNA-directed RNA polymerase subunit alpha, ...
著者Dey, S, Weixlbaumer, A.
登録日2022-07-05
公開日2022-10-26
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
6JNX
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BU of 6jnx by Molmil
Cryo-EM structure of a Q-engaged arrested complex
分子名称: Antiterminator Q protein, DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Feng, Y, Shi, J.
登録日2019-03-18
公開日2019-06-12
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.08 Å)
主引用文献Structural basis of Q-dependent transcription antitermination.
Nat Commun, 10, 2019
4ZH3
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BU of 4zh3 by Molmil
Crystal structure of Escherichia coli RNA polymerase in complex with CBRH16-Br
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Feng, Y, Ebright, R.H.
登録日2015-04-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.082 Å)
主引用文献Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Structure, 23, 2015
6UUC
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BU of 6uuc by Molmil
E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching ATP ("Fresh" crystal soaked with ATP for 2 hours)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.096 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UU1
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BU of 6uu1 by Molmil
E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Fresh" crystal soaked with CTP, GTP, and ddTTP for 30 minutes)
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.097 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6XH8
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BU of 6xh8 by Molmil
CueR-transcription activation complex with RNA transcript
分子名称: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Shi, W, Yang, Y.
登録日2020-06-18
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of copper-efflux-regulator-dependent transcription activation.
Iscience, 24, 2021
7PYK
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BU of 7pyk by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in more-swiveled conformation)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhu, C, Guo, X, Weixlbaumer, A.
登録日2021-10-10
公開日2022-03-23
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7PY7
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BU of 7py7 by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in more-swiveled conformation)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhu, C, Guo, X, Weixlbaumer, A.
登録日2021-10-09
公開日2022-03-23
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7PY6
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BU of 7py6 by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in less-swiveled conformation)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhu, C, Guo, X, Weixlbaumer, A.
登録日2021-10-09
公開日2022-03-23
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
8AC0
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BU of 8ac0 by Molmil
RNA polymerase at U-rich pause bound to regulatory RNA putL - active, closed clamp state
分子名称: DNA Non-template strand, DNA Template strand, DNA-directed RNA polymerase subunit alpha, ...
著者Weixlbaumer, A, Dey, S.
登録日2022-07-05
公開日2022-10-19
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
8AD1
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BU of 8ad1 by Molmil
RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Dey, S, Weixlbaumer, A.
登録日2022-07-07
公開日2022-10-19
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022

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件を2024-07-17に公開中

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