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PDB: 15 件

3PKB
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M. tuberculosis MetAP with bengamide analog Y16, in Mn form
分子名称: (E,2R,3R,4S,5R)-N-(2-azanyl-2-oxidanylidene-ethyl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, CHLORIDE ION, MANGANESE (II) ION, ...
著者Ye, Q.Z, Lu, J.P.
登録日2010-11-11
公開日2011-04-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
Chemmedchem, 6, 2011
3PKA
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M. tuberculosis MetAP with bengamide analog Y02, in Mn form
分子名称: (2R,3R,4S,5R,6E)-3,4,5-trihydroxy-2-methoxy-8,8-dimethyl-N-[2-(2,4,6-trimethylphenoxy)ethyl]non-6-enamide, CHLORIDE ION, MANGANESE (II) ION, ...
著者Ye, Q.Z, Lu, J.P.
登録日2010-11-11
公開日2011-04-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
Chemmedchem, 6, 2011
3IU7
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M. tuberculosis methionine aminopeptidase with Mn inhibitor A02
分子名称: 5-(2-CHLOROPHENYL)FURAN-2-CARBOXYLIC ACID, CHLORIDE ION, MANGANESE (II) ION, ...
著者Ye, Q.Z, Lu, J.P.
登録日2009-08-30
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
J.Med.Chem., 53, 2010
3PKD
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M. tuberculosis MetAP with bengamide analog Y10, in Mn form
分子名称: (E,2R,3R,4S,5R)-N-(2,3-dihydro-1H-inden-2-yl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, MANGANESE (II) ION, Methionine aminopeptidase
著者Ye, Q.Z, Lu, J.P.
登録日2010-11-11
公開日2011-04-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
Chemmedchem, 6, 2011
3PKC
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BU of 3pkc by Molmil
M. tuberculosis MetAP with bengamide analog Y08, in Mn form
分子名称: (E,2R,3R,4S,5R)-N-[[(3S)-1-cyclopropylcarbonylpiperidin-3-yl]methyl]-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, MANGANESE (II) ION, Methionine aminopeptidase
著者Ye, Q.Z, Lu, J.P.
登録日2010-11-11
公開日2011-04-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
Chemmedchem, 6, 2011
1Y1N
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BU of 1y1n by Molmil
Identification of SH3 motif in M. Tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome
分子名称: Methionine aminopeptidase 1B, POTASSIUM ION
著者Addlagatta, A, Quillin, M.L, Omotoso, O, Liu, J.O, Matthews, B.W.
登録日2004-11-18
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome
Biochemistry, 44, 2005
3PKE
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BU of 3pke by Molmil
M. tuberculosis MetAP with bengamide analog Y10, in Ni form
分子名称: (E,2R,3R,4S,5R)-N-(2,3-dihydro-1H-inden-2-yl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, CHLORIDE ION, Methionine aminopeptidase, ...
著者Ye, Q.Z, Lu, J.P.
登録日2010-11-11
公開日2011-04-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
Chemmedchem, 6, 2011
1YJ3
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BU of 1yj3 by Molmil
Crystal structure analysis of product bound methionine aminopeptidase Type 1c from Mycobacterium Tuberculosis
分子名称: BETA-MERCAPTOETHANOL, COBALT (II) ION, METHIONINE, ...
著者Addlagatta, A, Quillin, M.L, Omotoso, O, Liu, J.O, Matthews, B.W.
登録日2005-01-13
公開日2005-07-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome.
Biochemistry, 44, 2005
3IU9
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BU of 3iu9 by Molmil
M. tuberculosis methionine aminopeptidase with Ni inhibitor T07
分子名称: 5-[(2,4-dichlorobenzyl)sulfanyl]-4H-1,2,4-triazol-3-amine, CHLORIDE ION, Methionine aminopeptidase, ...
著者Ye, Q.Z, Lu, J.P.
登録日2009-08-30
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
J.Med.Chem., 53, 2010
3IU8
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BU of 3iu8 by Molmil
M. tuberculosis methionine aminopeptidase with Ni inhibitor T03
分子名称: 3-[(4-fluorobenzyl)sulfanyl]-4H-1,2,4-triazole, CHLORIDE ION, Methionine aminopeptidase, ...
著者Ye, Q.Z, Lu, J.P.
登録日2009-08-30
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
J.Med.Chem., 53, 2010
4OOK
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BU of 4ook by Molmil
Third Metal bound M.tuberculosis methionine aminopeptidase
分子名称: COBALT (II) ION, Methionine aminopeptidase 2, SODIUM ION
著者Reddi, R, Addlagatta, A.
登録日2014-02-03
公開日2015-02-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
4IEC
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BU of 4iec by Molmil
Cys105 covalent modification by 2-hydroxyethyl disulfide in Mycobacterium tuberculosis methionine aminopeptidase Type 1c
分子名称: COBALT (II) ION, Methionine aminopeptidase 2, POTASSIUM ION
著者Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A.
登録日2012-12-13
公開日2013-12-18
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
4IDY
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BU of 4idy by Molmil
Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with 2-hydroxyethyl disulfide
分子名称: 2-HYDROXYETHYL DISULFIDE, Methionine aminopeptidase 2, POTASSIUM ION
著者Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A.
登録日2012-12-13
公開日2013-12-18
最終更新日2015-02-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
4IF7
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BU of 4if7 by Molmil
Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with homocysteine-methyl disulfide
分子名称: (2S)-2-amino-4-(methyldisulfanyl)butanoic acid, COBALT (II) ION, Methionine aminopeptidase 2
著者Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A.
登録日2012-12-14
公開日2013-12-18
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
3ROR
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BU of 3ror by Molmil
Crystal structure of C105S mutant of Mycobacterium tuberculosis methionine aminopeptidase
分子名称: BETA-MERCAPTOETHANOL, COBALT (II) ION, Methionine aminopeptidase, ...
著者Reddi, R, Kishor, C, Addlagatta, A.
登録日2011-04-26
公開日2012-05-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of C105S mutant of Mycobacterium tuberculosis methionine aminopeptidase
To be Published

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件を2024-08-07に公開中

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