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PDB: 25 件

6RHV
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Crystal structure of mouse CD11b I-domain (CD11b-I) in complex with Staphylococcus aureus octameric bi-component leukocidin LukGH (LukH K319A mutant)
分子名称: Beta-channel forming cytolysin, DIMETHYL SULFOXIDE, Integrin alpha-M, ...
著者Trstenjak, N, Milic, D, Djinovic-Carugo, K, Badarau, A.
登録日2019-04-23
公開日2019-12-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity.
Proc.Natl.Acad.Sci.USA, 117, 2020
2LKJ
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Structures and Interaction Analyses of the Integrin Alpha-M Beta-2 Cytoplasmic Tails
分子名称: Integrin alpha-M
著者Chua, G.L, Tang, X.Y, Amalraj, M, Tan, S.M, Bhattacharjya, S.
登録日2011-10-12
公開日2011-11-02
最終更新日2024-11-20
実験手法SOLUTION NMR
主引用文献Structures and interaction analyses of the integrin alphaMbeta2 cytoplasmic tails
J.Biol.Chem., 2011
7P2D
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Structure of alphaMbeta2/Cd11bCD18 headpiece in complex with a nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Jensen, R.K, Andersen, G.R.
登録日2021-07-05
公開日2022-05-04
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into the function-modulating effects of nanobody binding to the integrin receptor alpha M beta 2.
J.Biol.Chem., 298, 2022
6RHW
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Crystal structure of human CD11b I-domain (CD11b-I) in complex with Staphylococcus aureus octameric bi-component leukocidin LukGH
分子名称: Beta-channel forming cytolysin, DIMETHYL SULFOXIDE, Integrin alpha-M, ...
著者Trstenjak, N, Milic, D, Djinovic-Carugo, K, Badarau, A.
登録日2019-04-23
公開日2019-12-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity.
Proc.Natl.Acad.Sci.USA, 117, 2020
7AKK
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Structure of a complement factor-receptor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ...
著者Fernandez, F.J, Santos-Lopez, J, Martinez-Barricarte, R, Querol-Garcia, J, Navas-Yuste, S, Savko, M, Shepard, W.E, Rodriguez de Cordoba, S, Vega, M.C.
登録日2020-10-01
公開日2022-04-13
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.395 Å)
主引用文献The crystal structure of iC3b-CR3 alpha I reveals a modular recognition of the main opsonin iC3b by the CR3 integrin receptor
Nat Commun, 13, 2022
4M76
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Integrin I domain of complement receptor 3 in complex with C3d
分子名称: Complement C3, Integrin alpha-M, NICKEL (II) ION
著者Bajic, G, Yatime, L, Vorup-Jensen, T, Andersen, G.R.
登録日2013-08-12
公開日2013-10-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3.
Proc.Natl.Acad.Sci.USA, 110, 2013
4XW2
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Structural basis for simvastatin competitive antagonism of complement receptor 3
分子名称: Integrin alpha-M, MAGNESIUM ION, Simvastatin acid
著者Bajic, G, Jensen, M.R, Vorup-Jensen, T, Andersen, G.R.
登録日2015-01-28
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural Basis for Simvastatin Competitive Antagonism of Complement Receptor 3.
J.Biol.Chem., 291, 2016
2LKE
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Structures and Interaction Analyses of the Integrin Alpha-M Beta-2 Cytoplasmic Tails
分子名称: Integrin alpha-M
著者Chua, G.L, Tang, X.Y, Amalraj, M, Bhattacharjya, S, Tan, S.M.
登録日2011-10-11
公開日2011-11-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structures and interaction analyses of the integrin alphaMbeta2 cytoplasmic tails
J.Biol.Chem., 2011
1BHQ
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MAC-1 I DOMAIN CADMIUM COMPLEX
分子名称: ACETYL GROUP, CADMIUM ION, CD11B
著者Baldwin, E.T.
登録日1998-06-10
公開日1998-11-04
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cation binding to the integrin CD11b I domain and activation model assessment
Structure, 6, 1998
1BHO
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MAC-1 I DOMAIN MAGNESIUM COMPLEX
分子名称: CD11B, MAGNESIUM ION
著者Baldwin, E.T.
登録日1998-06-10
公開日1998-11-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cation binding to the integrin CD11b I domain and activation model assessment
Structure, 6, 1998
8VOI
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HADDOCK models of active human alphaM I-domain bound to the the C-terminal domain of the cytokine pleiotrophin
分子名称: Integrin alpha-M, MAGNESIUM ION, Pleiotrophin
著者Wang, X, Nguyen, H.
登録日2024-01-15
公開日2024-05-15
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献NMR structure of alphaM I-domain of integrin Mac-1 in complex with the Cytokine Pleiotrophin
To Be Published
8VOH
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HADDOCK models of human alphaM I-domain bound to the the N-terminal domain of the cytokine pleiotrophin
分子名称: Integrin alpha-M, Pleiotrophin
著者Wang, X, Nguyen, H.
登録日2024-01-15
公開日2024-05-15
最終更新日2024-11-20
実験手法SOLUTION NMR
主引用文献NMR structure of alphaM I-domain of integrin Mac-1 in complex with the Cytokine Pleiotrophin
To Be Published
3QA3
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Crystal Structure of A-domain in complex with antibody
分子名称: 1,2-ETHANEDIOL, Antibody Heavy chain, Antibody Light chain, ...
著者Mahalingam, B, Xiong, J.P, Arnaout, M.A.
登録日2011-01-10
公開日2011-11-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design.
J.Immunol., 187, 2011
8CE9
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Crystal structure of human Cd11b I domain in C121 space group
分子名称: 1,2-ETHANEDIOL, Integrin alpha-M, SULFATE ION
著者Koekemoer, L, Williams, E, Ni, X, Gao, Q, Coker, J, MacLean, E.M, Wright, N.D, Marsden, B, Von Delft, F, Schwenzer, A, Midwood, K.
登録日2023-02-01
公開日2023-03-22
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Crystal structure of human Cd11b I domain in C121 space group
To Be Published
8CE6
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Crystal structure of human Cd11b I domain in P212121 space group
分子名称: CHLORIDE ION, GLYCEROL, Integrin alpha-M, ...
著者Koekemoer, L, Williams, E, Ni, X, Gao, Q, Coker, J, MacLean, E.M, Wright, N.D, Marsden, B, Von Delft, F, Schwenzer, A, Midwood, K.
登録日2023-02-01
公開日2023-03-22
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.582 Å)
主引用文献Crystal structure of human Cd11b I domain in P212121 space group
To Be Published
1N9Z
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INTEGRIN ALPHA M I DOMAIN MUTANT
分子名称: Integrin alpha-M, MAGNESIUM ION
著者McCleverty, C.J, Liddington, R.C.
登録日2002-11-26
公開日2003-05-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003
1NA5
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INTEGRIN ALPHA M I DOMAIN
分子名称: Integrin alpha-M
著者McCleverty, C.J, Liddington, R.C.
登録日2002-11-26
公開日2003-05-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003
7USL
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Integrin alphaM/beta2 ectodomain in complex with adenylate cyclase toxin RTX751 and M1F5 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-04-25
公開日2022-08-17
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
7USM
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Integrin alphaM/beta2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-04-25
公開日2022-08-17
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
3Q3G
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Crystal Structure of A-domain in complex with antibody
分子名称: 1,2-ETHANEDIOL, Antibody Heavy chain, Antibody Light Chain, ...
著者Mahalingam, B, Xiong, J.P, Arnaout, M.A.
登録日2010-12-21
公開日2011-11-30
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design.
J.Immunol., 187, 2011
1IDO
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I-DOMAIN FROM INTEGRIN CR3, MG2+ BOUND
分子名称: INTEGRIN, MAGNESIUM ION
著者Lee, J.-O, Liddington, R.
登録日1996-03-12
公開日1996-08-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18).
Cell(Cambridge,Mass.), 80, 1995
1JLM
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I-DOMAIN FROM INTEGRIN CR3, MN2+ BOUND
分子名称: INTEGRIN, MANGANESE (II) ION
著者Lee, J.-O, Liddington, R.
登録日1996-04-09
公開日1997-01-11
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Two conformations of the integrin A-domain (I-domain): a pathway for activation?
Structure, 3, 1995
1IDN
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MAC-1 I DOMAIN METAL FREE
分子名称: CD11B
著者Baldwin, E.T.
登録日1998-06-10
公開日1998-11-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cation binding to the integrin CD11b I domain and activation model assessment
Structure, 6, 1998
1M1U
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AN ISOLEUCINE-BASED ALLOSTERIC SWITCH CONTROLS AFFINITY AND SHAPE SHIFTING IN INTEGRIN CD11B A-DOMAIN
分子名称: CALCIUM ION, Integrin alpha-M
著者Xiong, J.-P, Li, R, Essafi, M, Stehle, T, Arnaout, M.A.
登録日2002-06-20
公開日2002-08-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain.
J.Biol.Chem., 275, 2000
1MF7
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INTEGRIN ALPHA M I DOMAIN
分子名称: INTEGRIN ALPHA M
著者McCleverty, C.J, Liddington, R.C.
登録日2002-08-09
公開日2003-05-20
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003

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