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PDB: 354 件
5VIZ
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BU of 5viz by Molmil
X-Ray structure of Insulin Glargine
分子名称: Insulin, chain alpha, chain beta
著者Reyes-Grajeda, J.P, Romero, A.
登録日2017-04-17
公開日2017-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献X-Ray structure of Insulin Glargine
To Be Published
2OLY
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BU of 2oly by Molmil
Structure of human insulin in presence of urea at pH 7.0
分子名称: CHLORIDE ION, GLYCEROL, Insulin A chain, ...
著者Norrman, M, Schluckebier, G.
登録日2007-01-20
公開日2007-12-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH.
Bmc Struct.Biol., 7, 2007
7S4Y
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BU of 7s4y by Molmil
Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - Insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Martin-Garcia, J.M, Botha, S, Hu, H, Jernigan, R, Castellvi, A, Lisova, S, Gil, F, Calisto, B, Crespo, I, Roy-Chowdbury, S, Grieco, A, Ketawala, G, Weierstall, U, Spence, J, Fromme, P, Zatsepin, N, Boer, R, Carpena, X.
登録日2021-09-09
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Serial macromolecular crystallography at ALBA Synchrotron Light Source.
J.Synchrotron Radiat., 29, 2022
4RXW
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BU of 4rxw by Molmil
Crystal Structure of the cobalt human insulin derivative
分子名称: COBALT (II) ION, Insulin A chain, Insulin B chain
著者Prugovecki, B, Ivetic, N, Matkovic-Calogovic, D.
登録日2014-12-12
公開日2015-01-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal Structure of the cobalt human insulin derivative
TO BE PUBLISHED
8ONP
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BU of 8onp by Molmil
Human insulin trans-HypB26-DTIA analogue
分子名称: Insulin A chain, Insulin B chain, SULFATE ION
著者Brzozowski, A.M, Zakova, L, Jiracek, J.
登録日2023-04-03
公開日2024-04-10
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Analogues of human insulin with specificity to insulin receptor isoform B
To Be Published
5BTS
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BU of 5bts by Molmil
Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin
分子名称: Insulin A chain, Insulin B chain
著者Norrman, M, Hjorth, C.F.
登録日2015-06-03
公開日2016-03-09
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin.
J.Pharm.Sci., 105, 2016
4GBC
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BU of 4gbc by Molmil
Crystal structure of aspart insulin at pH 6.5
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Lima, L.M.T.R, Favero-Retto, M.P, Palmieri, L.C.
登録日2012-07-27
公開日2013-06-12
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (1.778 Å)
主引用文献A T3R3 hexamer of the human insulin variant B28Asp.
Biophys.Chem., 173, 2013
1EV3
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BU of 1ev3 by Molmil
Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer
分子名称: CHLORIDE ION, INSULIN, M-CRESOL, ...
著者Smith, G.D, Ciszak, E, Magrum, L.A, Pangborn, W.A, Blessing, R.H.
登録日2000-04-19
公開日2000-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献R6 hexameric insulin complexed with m-cresol or resorcinol.
Acta Crystallogr.,Sect.D, 56, 2000
4EWZ
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BU of 4ewz by Molmil
Human Insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
登録日2012-04-29
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.791 Å)
主引用文献Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
7Z5Q
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BU of 7z5q by Molmil
Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and p-Hydroxyphenylpyruvate (HPP)
分子名称: Insulin, Insulin A chain, SULFATE ION
著者van den Elsen, J.M.H, Wahid, A.A, Crennell, S.J.
登録日2022-03-09
公開日2023-03-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling
To Be Published
6P4Z
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BU of 6p4z by Molmil
Structure of gadolinium-caged cobalt (III) insulin hexamer
分子名称: CHLORIDE ION, COBALT (II) ION, GADOLINIUM ATOM, ...
著者Tran, T.H, Taylor, S.K, Stojanovic, M.N, Tong, L.
登録日2019-05-29
公開日2019-06-12
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insulin Hexamer-Caged Gadolinium Ion as MRI Contrast-o-phore
ChemBioChem, 24, 2018
1XDA
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BU of 1xda by Molmil
STRUCTURE OF INSULIN
分子名称: CHLORIDE ION, FATTY ACID ACYLATED INSULIN, MYRISTIC ACID, ...
著者Whittingham, J.L, Havelund, S, Jonassen, I.
登録日1996-12-18
公開日1997-07-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a prolonged-acting insulin with albumin-binding properties.
Biochemistry, 36, 1997
5CO6
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BU of 5co6 by Molmil
Crystal structure of human zinc insulin at pH 6.5
分子名称: CHLORIDE ION, Insulin, MAGNESIUM ION, ...
著者Lima, L.M.T.R, PALMIERI, L.C.
登録日2015-07-19
公開日2015-08-26
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of human zinc insulin at pH 6.5
To Be Published
4IYF
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BU of 4iyf by Molmil
Insulin glargine crystal structure 2
分子名称: Insulin A chain, Insulin B chain
著者Barba de la Rosa, A.P, Lara-Gonzalez, S, Montero-Moran, G.M, Escobedo-Moratilla, A.
登録日2013-01-28
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Physicochemical and structural analysis of a biosimilar insulin glargine formulation and its reference
to be published
4AJZ
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BU of 4ajz by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-21
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
2VJZ
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BU of 2vjz by Molmil
Crystal structure form ultalente insulin microcrystals
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Wagner, A, Diez, J, Schulze-Briese, C, Schluckebier, G.
登録日2007-12-14
公開日2008-09-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Ultralente-A Microcrystalline Insulin Suspension.
Proteins, 74, 2009
1RWE
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BU of 1rwe by Molmil
Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues
分子名称: CHLORIDE ION, Insulin, PHENOL, ...
著者Wan, Z, Xu, B, Chu, Y.C, Li, B, Nakagawa, S.H, Qu, Y, Hu, S.Q, Katsoyannis, P.G, Weiss, M.A.
登録日2003-12-16
公開日2005-02-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues.
Biochemistry, 43, 2004
2CEU
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BU of 2ceu by Molmil
Despentapeptide insulin in acetic acid (pH 2)
分子名称: INSULIN, SULFATE ION
著者Whittingham, J.L, Zhang, Y, Zakova, L, Dodson, E.J, Turkenburg, J.P, Brange, J, Dodson, G.G.
登録日2006-02-10
公開日2006-03-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献I222 Crystal Form of Despentapeptide (B26-B30) Insulin Provides New Insights Into the Properties of Monomeric Insulin.
Acta Crystallogr.,Sect.D, 62, 2006
4F1A
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BU of 4f1a by Molmil
Human Insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
登録日2012-05-06
公開日2013-05-08
最終更新日2013-12-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4UNG
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BU of 4ung by Molmil
Human insulin B26Asn mutant crystal structure
分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION
著者Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M.
登録日2014-05-28
公開日2014-10-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex
Acta Crystallogr.,Sect.D, 70, 2014
6H3M
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BU of 6h3m by Molmil
The crystal structure of a human seleno-insulin analog
分子名称: Insulin
著者Lansky, S, Weil-Ktorza, O, Metanis, N, Shoham, G.
登録日2018-07-19
公開日2019-08-14
最終更新日2020-08-26
実験手法X-RAY DIFFRACTION (1.821 Å)
主引用文献Substitution of an Internal Disulfide Bridge with a Diselenide Enhances both Foldability and Stability of Human Insulin.
Chemistry, 25, 2019
3INC
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BU of 3inc by Molmil
Crystal structure of human insulin with Ni+2 complex
分子名称: Insulin A chain, Insulin B chain, NICKEL (II) ION
著者Raghavendra, N, Pattabhi, V, Rajan, S.S.
登録日2009-08-12
公開日2010-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin
To be Published
6VES
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BU of 6ves by Molmil
Human insulin analog: [GluB10,HisA8,ArgA9]-DOI
分子名称: Insulin A chain, Insulin B chain
著者Menting, J.G, Chou, D.H.-C, Lawrence, M.C, Xiong, X.
登録日2020-01-02
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mini-Ins: A Minimal, Bioactive Insulin Analog with Alternative Binding Modes
To Be Published
4Z77
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BU of 4z77 by Molmil
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2015-04-06
公開日2015-06-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
To Be Published
3I40
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BU of 3i40 by Molmil
Human insulin
分子名称: Insulin A chain, Insulin B chain
著者Timofeev, V.I, Bezuglov, V.V, Miroshnikov, K.A, Chuprov-Netochin, R.N, Kuranova, I.P.
登録日2009-07-01
公開日2010-01-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid.
Acta Crystallogr.,Sect.F, 66, 2010

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