1UBS
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![BU of 1ubs by Molmil](/molmil-images/mine/1ubs) | TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) WITH A MUTATION OF LYS 87->THR IN THE B SUBUNIT AND IN THE PRESENCE OF LIGAND L-SERINE | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, SERINE, SODIUM ION, ... | 著者 | Rhee, S, Parris, K, Ahmed, S.A, Miles, E.W, Davies, D.R. | 登録日 | 1995-12-14 | 公開日 | 1996-03-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes. Biochemistry, 36, 1997
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1TTQ
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![BU of 1ttq by Molmil](/molmil-images/mine/1ttq) | TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) IN THE PRESENCE OF POTASSIUM AT ROOM TEMPERATURE | 分子名称: | POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE, TRYPTOPHAN SYNTHASE | 著者 | Rhee, S, Parris, K, Ahmed, S, Miles, E.W, Davies, D.R. | 登録日 | 1995-10-11 | 公開日 | 1996-03-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex. Biochemistry, 35, 1996
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1A5B
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![BU of 1a5b by Molmil](/molmil-images/mine/1a5b) | CRYO-CRYSTALLOGRAPHY OF A TRUE SUBSTRATE, INDOLE-3-GLYCEROL PHOSPHATE, BOUND TO A MUTANT (ALPHA D60N) TRYPTOPHAN SYNTHASE ALPHA2BETA2 COMPLEX REVEALS THE CORRECT ORIENTATION OF ACTIVE SITE ALPHA GLU 49 | 分子名称: | INDOLE-3-GLYCEROL PHOSPHATE, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Rhee, S, Miles, E.W, Davies, D.R. | 登録日 | 1998-02-12 | 公開日 | 1998-05-27 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Cryo-crystallography of a true substrate, indole-3-glycerol phosphate, bound to a mutant (alphaD60N) tryptophan synthase alpha2beta2 complex reveals the correct orientation of active site alphaGlu49. J.Biol.Chem., 273, 1998
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2RHG
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![BU of 2rhg by Molmil](/molmil-images/mine/2rhg) | Tryptophan synthase complexed with IGP, pH 7.0, internal aldimine | 分子名称: | INDOLE-3-GLYCEROL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | 著者 | Kulik, V, Barends, T, Schlichting, I. | 登録日 | 2007-10-09 | 公開日 | 2007-11-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Tryptophan synthase complexed with IGP, pH 7.0, internal aldimine To be Published
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1CW2
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![BU of 1cw2 by Molmil](/molmil-images/mine/1cw2) | CRYSTAL STRUCTURE OF THE COMPLEX OF BACTERIAL TRYPTOPHAN SYNTHASE WITH THE TRANSITION STATE ANALOGUE INHIBITOR 4-(2-HYDROXYPHENYLSULFINYL)-BUTYLPHOSPHONIC ACID | 分子名称: | 4-(2-HYDROXYPHENYLSULFINYL)-BUTYLPHOSPHONIC ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | 著者 | Sachpatzidis, A, Dealwis, C, Lubetsky, J.B, Liang, P.H, Anderson, K.S, Lolis, E. | 登録日 | 1999-08-25 | 公開日 | 1999-12-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallographic studies of phosphonate-based alpha-reaction transition-state analogues complexed to tryptophan synthase. Biochemistry, 38, 1999
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2TRS
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![BU of 2trs by Molmil](/molmil-images/mine/2trs) | CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES | 分子名称: | INDOLE-3-PROPANOL PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE, ... | 著者 | Rhee, S, Parris, K.D, Hyde, C.C, Ahmed, S.A, Miles, E.W, Davies, D.R. | 登録日 | 1997-01-07 | 公開日 | 1997-04-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes. Biochemistry, 36, 1997
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8B05
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![BU of 8b05 by Molmil](/molmil-images/mine/8b05) | TRYPTOPHAN SYNTHASE - Cryo-trapping by the spitrobot crystal plunger after 20 sec | 分子名称: | CESIUM ION, CHLORIDE ION, INDOLE, ... | 著者 | Mehrabi, P, Sung, S, von Stetten, D, Prester, A, Hatton, C.E, Kleine-Dopke, S, Berkes, A, Gore, G, Leimkohl, J.P, Schikora, H, Kollewe, M, Rohde, H, Wilmanns, M, Tellkamp, F, Schulz, E.C. | 登録日 | 2022-09-07 | 公開日 | 2023-05-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography. Nat Commun, 14, 2023
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3CEP
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![BU of 3cep by Molmil](/molmil-images/mine/3cep) | Structure of a tryptophan synthase quinonoid intermediate | 分子名称: | 3-hydroxy-2-iminopropanoic acid, CESIUM ION, INDOLINE, ... | 著者 | Barends, T.R.M, Domratcheva, T, Kulik, V, Blumenstein, L, Dunn, M.F, Schlichting, I. | 登録日 | 2008-02-29 | 公開日 | 2008-04-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and mechanistic implications of a tryptophan synthase quinonoid intermediate. Chembiochem, 9, 2008
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6XNC
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![BU of 6xnc by Molmil](/molmil-images/mine/6xnc) | |
8EYS
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![BU of 8eys by Molmil](/molmil-images/mine/8eys) | |
1C8V
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![BU of 1c8v by Molmil](/molmil-images/mine/1c8v) | CRYSTAL STRUCTURE OF THE COMPLEX OF BACTERIAL TRYPTOPHAN SYNTHASE WITH THE TRANSITION STATE ANALOGUE INHIBITOR 4-(2-HYDROXYPHENYLTHIO)-BUTYLPHOSPHONIC ACID | 分子名称: | 4-(2-HYDROXYPHENYLTHIO)-1-BUTENYLPHOSPHONIC ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | 著者 | Sachpatzidis, A, Dealwis, C, Lubetsky, J.B, Liang, P.H, Anderson, K.S, Lolis, E. | 登録日 | 1999-07-30 | 公開日 | 2000-01-13 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystallographic studies of phosphonate-based alpha-reaction transition-state analogues complexed to tryptophan synthase. Biochemistry, 38, 1999
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1BKS
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![BU of 1bks by Molmil](/molmil-images/mine/1bks) | TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) FROM SALMONELLA TYPHIMURIUM | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE | 著者 | Hyde, C.C. | 登録日 | 1998-07-10 | 公開日 | 1999-03-23 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex. Biochemistry, 35, 1996
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8B03
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![BU of 8b03 by Molmil](/molmil-images/mine/8b03) | TRYPTOPHAN SYNTHASE - Cryo-trapping by the spitrobot crystal plunger after 0 sec | 分子名称: | CESIUM ION, CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Mehrabi, P, Sung, S, von Stetten, D, Prester, A, Hatton, C.E, Kleine-Dopke, S, Berkes, A, Gore, G, Leimkohl, J.P, Schikora, H, Kollewe, M, Rohde, H, Wilmanns, M, Tellkamp, F, Schulz, E.C. | 登録日 | 2022-09-07 | 公開日 | 2023-05-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography. Nat Commun, 14, 2023
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1FUY
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![BU of 1fuy by Molmil](/molmil-images/mine/1fuy) | |
1K7E
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![BU of 1k7e by Molmil](/molmil-images/mine/1k7e) | CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID | 分子名称: | N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | 著者 | Weyand, M, Schlichting, I, Marabotti, A, Mozzarelli, A. | 登録日 | 2001-10-19 | 公開日 | 2002-07-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of a new class of allosteric effectors complexed to tryptophan synthase. J.Biol.Chem., 277, 2002
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1TTP
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![BU of 1ttp by Molmil](/molmil-images/mine/1ttp) | TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) IN THE PRESENCE OF CESIUM, ROOM TEMPERATURE | 分子名称: | CESIUM ION, PYRIDOXAL-5'-PHOSPHATE, TRYPTOPHAN SYNTHASE | 著者 | Rhee, S, Parris, K, Ahmed, S, Miles, E.W, Davies, D.R. | 登録日 | 1995-10-11 | 公開日 | 1996-03-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex. Biochemistry, 35, 1996
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1C9D
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![BU of 1c9d by Molmil](/molmil-images/mine/1c9d) | |
1A50
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![BU of 1a50 by Molmil](/molmil-images/mine/1a50) | CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUOROINDOLE PROPANOL PHOSPHATE | 分子名称: | 5-FLUOROINDOLE PROPANOL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | 著者 | Schneider, T.R, Gerhardt, E, Lee, M, Liang, P.-H, Anderson, K.S, Schlichting, I. | 登録日 | 1998-02-18 | 公開日 | 1999-03-30 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Loop closure and intersubunit communication in tryptophan synthase. Biochemistry, 37, 1998
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1A5S
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![BU of 1a5s by Molmil](/molmil-images/mine/1a5s) | CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUOROINDOLE PROPANOL PHOSPHATE AND L-SER BOUND AS AMINO ACRYLATE TO THE BETA SITE | 分子名称: | 5-FLUOROINDOLE PROPANOL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SERINE, ... | 著者 | Schneider, T.R, Gerhardt, E, Lee, M, Liang, P.-H, Anderson, K.S, Schlichting, I. | 登録日 | 1998-02-17 | 公開日 | 1999-03-30 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Loop closure and intersubunit communication in tryptophan synthase. Biochemistry, 37, 1998
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1CX9
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![BU of 1cx9 by Molmil](/molmil-images/mine/1cx9) | CRYSTAL STRUCTURE OF THE COMPLEX OF BACTERIAL TRYPTOPHAN SYNTHASE WITH THE TRANSITION STATE ANALOGUE INHIBITOR 4-(2-AMINOPHENYLTHIO)-BUTYLPHOSPHONIC ACID | 分子名称: | 4-(2-AMINOPHENYLTHIO)-BUTYLPHOSPHONIC ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | 著者 | Sachpatzidis, A, Dealwis, C, Lubetsky, J.B, Liang, P.H, Anderson, K.S, Lolis, E. | 登録日 | 1999-08-29 | 公開日 | 1999-12-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystallographic studies of phosphonate-based alpha-reaction transition-state analogues complexed to tryptophan synthase. Biochemistry, 38, 1999
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1C29
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![BU of 1c29 by Molmil](/molmil-images/mine/1c29) | CRYSTAL STRUCTURE OF THE COMPLEX OF BACTERIAL TRYPTOPHAN SYNTHASE WITH THE TRANSITION STATE ANALOGUE INHIBITOR 4-(2-HYDROXYPHENYLTHIO)-1-BUTENYLPHOSPHONIC ACID | 分子名称: | 4-(2-HYDROXYPHENYLTHIO)-1-BUTENYLPHOSPHONIC ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | 著者 | Sachpatzidis, A, Dealwis, C, Lubetsky, J.B, Liang, P.H, Anderson, K.S, Lolis, E. | 登録日 | 1999-07-23 | 公開日 | 2000-01-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystallographic studies of phosphonate-based alpha-reaction transition-state analogues complexed to tryptophan synthase. Biochemistry, 38, 1999
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1KFK
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![BU of 1kfk by Molmil](/molmil-images/mine/1kfk) | Crystal structure of Tryptophan Synthase From Salmonella Typhimurium | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ... | 著者 | Kulik, V, Weyand, M, Seidel, R, Niks, D, Arac, D, Dunn, M.F, Schlichting, I. | 登録日 | 2001-11-21 | 公開日 | 2003-10-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase. J.Mol.Biol., 324, 2002
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8B06
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![BU of 8b06 by Molmil](/molmil-images/mine/8b06) | TRYPTOPHAN SYNTHASE - Cryo-trapping by the spitrobot crystal plunger after 25 sec | 分子名称: | CESIUM ION, CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Mehrabi, P, Sung, S, von Stetten, D, Prester, A, Hatton, C.E, Kleine-Dopke, S, Berkes, A, Gore, G, Leimkohl, J.P, Schikora, H, Kollewe, M, Rohde, H, Wilmanns, M, Tellkamp, F, Schulz, E.C. | 登録日 | 2022-09-07 | 公開日 | 2023-05-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography. Nat Commun, 14, 2023
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8B08
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![BU of 8b08 by Molmil](/molmil-images/mine/8b08) | TRYPTOPHAN SYNTHASE - Cryo-trapping by the spitrobot crystal plunger after 30 sec | 分子名称: | CESIUM ION, CHLORIDE ION, SN-GLYCEROL-3-PHOSPHATE, ... | 著者 | Mehrabi, P, Sung, S, von Stetten, D, Prester, A, Hatton, C.E, Kleine-Dopke, S, Berkes, A, Gore, G, Leimkohl, J.P, Schikora, H, Kollewe, M, Rohde, H, Wilmanns, M, Tellkamp, F, Schulz, E.C. | 登録日 | 2022-09-07 | 公開日 | 2023-05-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography. Nat Commun, 14, 2023
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7A20
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![BU of 7a20 by Molmil](/molmil-images/mine/7a20) | |