5UGG
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![BU of 5ugg by Molmil](/molmil-images/mine/5ugg) | Protease Inhibitor | 分子名称: | Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(quinolin-2-yl)methyl]-L-tyrosinamide, Plasminogen | 著者 | Law, R.H.P, Wu, G, Whisstock, J.C. | 登録日 | 2017-01-08 | 公開日 | 2017-05-31 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors. Blood Adv, 1, 2017
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6D3Y
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5UGD
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![BU of 5ugd by Molmil](/molmil-images/mine/5ugd) | Protease Inhibitor | 分子名称: | Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(pyridin-4-yl)methyl]-L-tyrosinamide, Plasminogen | 著者 | Law, R.H.P, Wu, G, Whisstock, J.C. | 登録日 | 2017-01-08 | 公開日 | 2017-05-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors. Blood Adv, 1, 2017
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6D40
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8F7U
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![BU of 8f7u by Molmil](/molmil-images/mine/8f7u) | Macrocyclic Plasmin Inhibitor | 分子名称: | (5S,8R,18S,21R)-N-{[4-(aminomethyl)phenyl]methyl}-21-[(benzenesulfonyl)amino]-3,11,20-trioxo-2,5,8,12,19-pentaazatetracyclo[21.2.2.2~5,8~.2~13,16~]hentriaconta-1(25),13,15,23,26,28-hexaene-18-carboxamide, Activation peptide, GLYCEROL, ... | 著者 | Guojie, W. | 登録日 | 2022-11-20 | 公開日 | 2023-02-08 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Synthesis and structural characterization of new macrocyclicplasmin inhibitors Chemmedchem, 2023
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7UAH
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![BU of 7uah by Molmil](/molmil-images/mine/7uah) | Macrocyclic plasmin inhibitor | 分子名称: | (2~{R})-butane-1,2-diol, (6S,9R,19S,22R)-N-{[4-(aminomethyl)phenyl]methyl}-22-[(3-chlorobenzene-1-sulfonyl)amino]-3,12,21-trioxo-2,6,9,13,20-pentaazatetracyclo[22.2.2.2~6,9~.2~14,17~]dotriaconta-1(26),14,16,24,27,29-hexaene-19-carboxamide, Plasminogen, ... | 著者 | Guojie, W. | 登録日 | 2022-03-12 | 公開日 | 2023-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors. Chemmedchem, 18, 2023
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8F7V
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![BU of 8f7v by Molmil](/molmil-images/mine/8f7v) | Macrocyclic plasmin inhibitor | 分子名称: | (6S,9R,19S,22R)-N-{[4-(aminomethyl)phenyl]methyl}-22-[(benzenesulfonyl)amino]-3,12,21-trioxo-2,6,9,13,20-pentaazatetracyclo[22.2.2.2~6,9~.2~14,17~]dotriaconta-1(26),14,16,24,27,29-hexaene-19-carboxamide, GLYCEROL, Plasminogen, ... | 著者 | Guojie, W. | 登録日 | 2022-11-20 | 公開日 | 2023-02-08 | 最終更新日 | 2023-06-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Synthesis and structural characterization of new macrocyclicplasmin inhibitors Chemmedchem, 2023
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5HPG
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1KRN
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![BU of 1krn by Molmil](/molmil-images/mine/1krn) | STRUCTURE OF KRINGLE 4 AT 4C TEMPERATURE AND 1.67 ANGSTROMS RESOLUTION | 分子名称: | PLASMINOGEN, SULFATE ION | 著者 | Stec, B, Teeter, M.M, Whitlow, M, Yamano, A. | 登録日 | 1995-06-21 | 公開日 | 1997-01-11 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structure of human plasminogen kringle 4 at 1.68 a and 277 K. A possible structural role of disordered residues. Acta Crystallogr.,Sect.D, 53, 1997
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6OG4
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![BU of 6og4 by Molmil](/molmil-images/mine/6og4) | plasminogen binding group A streptococcal M protein | 分子名称: | Plasminogen, Plasminogen-binding group A streptococcal M-like protein PAM, SULFATE ION | 著者 | Law, R.H.P, Quek, A.J, Whisstock, J.C, Caradoc-Davies, T.T. | 登録日 | 2019-04-01 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding. J.Mol.Biol., 431, 2019
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1KI0
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![BU of 1ki0 by Molmil](/molmil-images/mine/1ki0) | The X-ray Structure of Human Angiostatin | 分子名称: | ANGIOSTATIN, BICINE | 著者 | Abad, M.C, Arni, R.K, Grella, D.K, Castellino, F.J, Tulinsky, A, Geiger, J.H. | 登録日 | 2001-12-02 | 公開日 | 2002-05-29 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin. J.Mol.Biol., 318, 2002
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4CIK
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![BU of 4cik by Molmil](/molmil-images/mine/4cik) | plasminogen kringle 1 in complex with inhibitor | 分子名称: | 5-[(2R,4S)-2-(phenylmethyl)piperidin-4-yl]-1,2-oxazol-3-one, PLASMINOGEN | 著者 | Xue, Y, Johansson, C, Cheng, L, Pettersen, D, Gustafsson, D. | 登録日 | 2013-12-10 | 公開日 | 2014-06-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Discovery of the Fibrinolysis Inhibitor Azd6564, Acting Via Interference of a Protein-Protein Interaction. Acs Med.Chem.Lett., 5, 2014
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6D3X
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7THS
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![BU of 7ths by Molmil](/molmil-images/mine/7ths) | Macrocyclic plasmin inhibitor | 分子名称: | (2S)-butane-1,2-diol, (6S,9R,20R,23S)-N-{[4-(aminomethyl)phenyl]methyl}-20-[(benzenesulfonyl)amino]-3,13,21-trioxo-2,6,9,14,22-pentaazatetracyclo[23.2.2.2~6,9~.2~15,18~]tritriaconta-1(27),15,17,25,28,30-hexaene-23-carboxamide, Plasminogen, ... | 著者 | Guojie, W. | 登録日 | 2022-01-12 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors. Chemmedchem, 18, 2023
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1PK4
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7E50
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![BU of 7e50 by Molmil](/molmil-images/mine/7e50) | Crystal structure of human microplasmin in complex with kazal-type inhibitor AaTI | 分子名称: | AAEL006007-PA, GLYCEROL, Plasminogen, ... | 著者 | Varsha, A.W, Jobichen, C, Mok, Y.K. | 登録日 | 2021-02-16 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of Aedes aegypti trypsin inhibitor in complex with mu-plasmin reveals role for scaffold stability in Kazal-type serine protease inhibitor. Protein Sci., 31, 2022
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1DDJ
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![BU of 1ddj by Molmil](/molmil-images/mine/1ddj) | CRYSTAL STRUCTURE OF HUMAN PLASMINOGEN CATALYTIC DOMAIN | 分子名称: | PLASMINOGEN | 著者 | Wang, X, Terzyan, S, Tang, J, Loy, J, Lin, X, Zhang, X. | 登録日 | 1999-11-10 | 公開日 | 2000-02-18 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Human plasminogen catalytic domain undergoes an unusual conformational change upon activation. J.Mol.Biol., 295, 2000
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6D3Z
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![BU of 6d3z by Molmil](/molmil-images/mine/6d3z) | Protease SFTI complex | 分子名称: | Plasminogen, Trypsin inhibitor 1 | 著者 | Law, R.H.P, Wu, G. | 登録日 | 2018-04-17 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. J. Med. Chem., 62, 2019
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1QRZ
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![BU of 1qrz by Molmil](/molmil-images/mine/1qrz) | CATALYTIC DOMAIN OF PLASMINOGEN | 分子名称: | PLASMINOGEN | 著者 | Peisach, E, Wang, J, de los Santos, T, Reich, E, Ringe, D. | 登録日 | 1999-06-16 | 公開日 | 1999-10-14 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the proenzyme domain of plasminogen. Biochemistry, 38, 1999
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4DCB
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![BU of 4dcb by Molmil](/molmil-images/mine/4dcb) | Y. pestis Plasminogen Activator Pla in Complex with Human Plasminogen Activation Loop Peptide ALP11 | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ... | 著者 | Eren, E, van den Berg, B. | 登録日 | 2012-01-17 | 公開日 | 2012-06-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.033 Å) | 主引用文献 | Structural basis for activation of an integral membrane protease by lipopolysaccharide. J.Biol.Chem., 287, 2012
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1CEA
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1CEB
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2PK4
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1PMK
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1RJX
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![BU of 1rjx by Molmil](/molmil-images/mine/1rjx) | Human PLASMINOGEN CATALYTIC DOMAIN, K698M MUTANT | 分子名称: | Plasminogen, SULFATE ION | 著者 | Terzyan, S, Wakeham, N, Zhai, P, Rodgers, K, Zhang, X.C. | 登録日 | 2003-11-20 | 公開日 | 2003-12-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Characterization of Lys-698 to met substitution in human plasminogen catalytic domain Proteins, 56, 2004
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