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PDB: 11 件
4U89
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4'-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis
分子名称: COENZYME A, IMIDAZOLE, PHOSPHATE ION, ...
著者Faille, A, Mourey, L, Pedelacq, J.D.
登録日2014-08-01
公開日2015-08-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献X-ray structure of the 4'-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis
to be published
7N8M
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PptT PAP(CoA) 8978B complex
分子名称: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
著者Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2021-06-15
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
4QJK
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Crystal structure of M. tuberculosis phosphopantetheinyl transferase PptT
分子名称: COENZYME A, Phosphopantetheinyl transferase PptT, SULFATE ION
著者Noel, J.P, Burkart, M.D, Vickery, C.R.
登録日2014-06-04
公開日2014-07-16
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria.
Acs Chem.Biol., 9, 2014
7ED0
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Transferase from Mycobacterium tuberculosis
分子名称: 4'-phosphopantetheinyl transferase superfamily protein, COENZYME A, SULFATE ION
著者Kim, D.-G, Lee, B.-J, Lee, S.J.
登録日2021-03-15
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Transferase from Mycobacterium tuberculosis
To Be Published
8QZH
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BU of 8qzh by Molmil
Crystal structure of apo-PptT from Mycobacterium tuberculosis
分子名称: 4'-phosphopantetheinyl transferase PptT, ACETATE ION, MAGNESIUM ION
著者Gavalda, S, Carivenc, C, Mourey, L, Pedelacq, J.D.
登録日2023-10-27
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases
Acs Catalysis, 14, 2024
7N8E
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PptT PAP(CoA) 9056 complex
分子名称: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
著者Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2021-06-14
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
4QVH
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Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein
分子名称: CITRATE ANION, COENZYME A, GLYCEROL, ...
著者Jung, J, Bashiri, G, Johnston, J.M, Baker, E.N.
登録日2014-07-15
公開日2014-12-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein.
J.Struct.Biol., 188, 2014
8QZJ
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Crystal structure of PptT-ADP from Mycobacterium tuberculosis
分子名称: 4'-phosphopantetheinyl transferase PptT, ADENOSINE-3'-5'-DIPHOSPHATE, MANGANESE (II) ION
著者Gavalda, S, Mourey, L, Pedelacq, J.D.
登録日2023-10-27
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases
Acs Catalysis, 14, 2024
7N8L
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BU of 7n8l by Molmil
PptT PAP(CoA) 9016 complex
分子名称: 4'-phosphopantetheinyl transferase PptT, COENZYME A, DIMETHYL SULFOXIDE, ...
著者Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2021-06-15
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.
J.Med.Chem., 65, 2022
8GKF
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Phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis in complex with Raltitrexed.
分子名称: 4'-phosphopantetheinyl transferase PptT, TOMUDEX
著者Krieger, I.V, Singh, A, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2023-03-18
公開日2024-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.
Sci Adv, 10, 2024
8QZI
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Crystal structure of PptT-ACP from Mycobacterium tuberculosis
分子名称: 4'-phosphopantetheinyl transferase PptT, COENZYME A, ISOPROPYL ALCOHOL, ...
著者Gavalda, S, Mourey, L, Pedelacq, J.D.
登録日2023-10-27
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases
Acs Catalysis, 14, 2024

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件を2024-07-10に公開中

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