6P5N
 
 | | Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1 | | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | 著者 | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | | 登録日 | 2019-05-30 | | 公開日 | 2019-09-25 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
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6D90
 | | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-site tRNA and eRF1. | | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | 著者 | Pisareva, V.P, Pisarev, A.V, Fernandez, I.S. | | 登録日 | 2018-04-27 | | 公開日 | 2018-06-06 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES.
Elife, 7, 2018
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7JQC
 | | SARS-CoV-2 Nsp1, CrPV IRES and rabbit 40S ribosome complex | | 分子名称: | 40S ribosomal protein S21, 40S ribosomal protein S24, 40S ribosomal protein S26, ... | | 著者 | Yuan, S, Xiong, Y. | | 登録日 | 2020-08-10 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA.
Mol.Cell, 80, 2020
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8P09
 | | 48S late-stage initiation complex with non methylated mRNA | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | | 著者 | Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y. | | 登録日 | 2023-05-09 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | N 6 -methyladenosine in 5' UTR does not promote translation initiation.
Mol.Cell, 84, 2024
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6MTD
 | | Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel) | | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | | 登録日 | 2018-10-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2019-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
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5LZS
 | | Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B | | 分子名称: | (2~{S})-~{N}-[(2~{R})-1-[[(3~{S},6~{S},8~{S},12~{S},13~{R},16~{S},17~{R},20~{S},23~{S})-13-[(2~{S})-butan-2-yl]-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-12-oxidanyl-2,5,7,10,15,19,22-heptakis(oxidanylidene)-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-~{N}-methyl-1-[(2~{S})-2-oxidanylpropanoyl]pyrrolidine-2-carboxamide, 18S ribosomal RNA, 28S ribosomal RNA, ... | | 著者 | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | 登録日 | 2016-10-02 | | 公開日 | 2016-11-30 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | | 主引用文献 | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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5LZV
 | | Structure of the mammalian ribosomal termination complex with accommodated eRF1(AAQ) and ABCE1. | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | 著者 | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | 登録日 | 2016-10-02 | | 公開日 | 2016-11-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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6W2T
 | | Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the closed state (Class 2) | | 分子名称: | 18S rRNA, CrPV 5'-UTR IRES, Eukaryotic translation initiation factor 3 subunit A, ... | | 著者 | Neupane, R, Pisareva, V, Rodriguez, C.F, Pisarev, A, Fernandez, I.S. | | 登録日 | 2020-03-08 | | 公開日 | 2020-04-22 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate.
Elife, 9, 2020
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6MTE
 | | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | | 登録日 | 2018-10-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2019-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
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6MTC
 | | Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state) | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | | 登録日 | 2018-10-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2019-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
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3JAH
 | | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | 著者 | Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. | | 登録日 | 2015-06-10 | | 公開日 | 2015-08-12 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
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5LZZ
 | | Structure of the mammalian rescue complex with Pelota and Hbs1l (combined) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | 著者 | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | 登録日 | 2016-10-02 | | 公開日 | 2016-11-30 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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6W2S
 | | Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the open state (Class 1) | | 分子名称: | 18S rRNA, CrPV 5'-UTR IRES, Eukaryotic translation initiation factor 3 subunit A, ... | | 著者 | Neupane, R, Pisareva, V, Rodriguez, C.F, Pisarev, A, Fernandez, I.S. | | 登録日 | 2020-03-08 | | 公開日 | 2020-04-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate.
Elife, 9, 2020
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6YAN
 | | Mammalian 48S late-stage translation initiation complex with histone 4 mRNA | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... | | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | | 登録日 | 2020-03-12 | | 公開日 | 2020-04-08 | | 最終更新日 | 2020-04-22 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
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6ZVK
 | | The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest possible initiation mechanism | | 分子名称: | 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES17, ... | | 著者 | Abaeva, I.S, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T, Hashem, Y, Hellen, C.U.T. | | 登録日 | 2020-07-24 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
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7SYS
 | | Structure of the delta dII IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(delta dII). | | 分子名称: | 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ... | | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | | 登録日 | 2021-11-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
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8BTK
 | | Structure of the TRAP complex with the Sec translocon and a translating ribosome | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Jaskolowski, M, Jomaa, A, Gamerdinger, M, Shrestha, S, Leibundgut, M, Deuerling, E, Ban, N. | | 登録日 | 2022-11-29 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular basis of the TRAP complex function in ER protein biogenesis.
Nat.Struct.Mol.Biol., 30, 2023
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5LZW
 | | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA. | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | 著者 | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | 登録日 | 2016-10-02 | | 公開日 | 2016-11-30 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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6GZ3
 | | tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-1 (TI-POST-1) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | 著者 | Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V. | | 登録日 | 2018-07-03 | | 公開日 | 2018-12-05 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
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6YAM
 | | Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ... | | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | | 登録日 | 2020-03-12 | | 公開日 | 2020-04-08 | | 最終更新日 | 2020-04-22 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
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6MTB
 | | Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state) | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | | 登録日 | 2018-10-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2019-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
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7A01
 | | The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism | | 分子名称: | 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES21, ... | | 著者 | Abaeva, I, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T.V, Hashem, Y, Hellen, C.U.T. | | 登録日 | 2020-08-05 | | 公開日 | 2020-12-30 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
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7SYR
 | | Structure of the wt IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(wt). | | 分子名称: | 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ... | | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | | 登録日 | 2021-11-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
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3JAG
 | | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | 著者 | Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. | | 登録日 | 2015-06-10 | | 公開日 | 2015-08-12 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
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5LZT
 | | Structure of the mammalian ribosomal termination complex with eRF1 and eRF3. | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | 著者 | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | 登録日 | 2016-10-02 | | 公開日 | 2016-11-30 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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