6XZ7
 
 | | E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet). | | 分子名称: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | | 著者 | Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L. | | 登録日 | 2020-02-03 | | 公開日 | 2020-07-22 | | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | | 主引用文献 | Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to theE. coli70S ribosome.
Rna, 26, 2020
|
|
4YBB
 | | High-resolution structure of the Escherichia coli ribosome | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | | 著者 | Noeske, J, Wasserman, M.R, Terry, D.S, Altman, R.B, Blanchard, S.C, Cate, J.H.D. | | 登録日 | 2015-02-18 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | High-resolution structure of the Escherichia coli ribosome.
Nat.Struct.Mol.Biol., 22, 2015
|
|
6PJ6
 | | High resolution cryo-EM structure of E.coli 50S | | 分子名称: | 23S rRNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | | 著者 | Stojkovic, V, Myasnikov, A, Frost, A, Fujimori, D.G. | | 登録日 | 2019-06-27 | | 公開日 | 2020-01-22 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Assessment of the nucleotide modifications in the high-resolution cryo-electron microscopy structure of the Escherichia coli 50S subunit.
Nucleic Acids Res., 48, 2020
|
|
7N1P
 | | Elongating 70S ribosome complex in a classical pre-translocation (PRE-C) conformation | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, S.K, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.33 Å) | | 主引用文献 | Structural basis of early translocation events on the ribosome.
Nature, 595, 2021
|
|
7PJS
 | | Structure of the 70S ribosome with tRNAs in the classical pre-translocation state and apramycin (C) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | | 登録日 | 2021-08-24 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.35 Å) | | 主引用文献 | Structural mechanism of GTPase-powered ribosome-tRNA movement
Nat Commun, 12, 2021
|
|
7YLA
 | | Cryo-EM structure of 50S-HflX complex | | 分子名称: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Damu, W, Ning, G. | | 登録日 | 2022-07-25 | | 公開日 | 2023-01-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | | 主引用文献 | Cryo-EM Structure of the 50S-HflX Complex Reveals a Novel Mechanism of Antibiotic Resistance in E. coli
Biorxiv, 2022
|
|
6XZB
 | | E. coli 70S ribosome in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet) (focused classification). | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L. | | 登録日 | 2020-02-03 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | | 主引用文献 | Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome.
Rna, 26, 2020
|
|
7N2V
 | | Elongating 70S ribosome complex in a spectinomycin-stalled intermediate state of translocation bound to EF-G in an active, GTP conformation (INT1) | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | | 登録日 | 2021-05-29 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | | 主引用文献 | Structural basis of early translocation events on the ribosome.
Nature, 595, 2021
|
|
7SA4
 | | Damaged 70S ribosome with PrfH bound | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Tian, Y, Zeng, F, Raybarman, A, Carruthers, A, Li, Q, Fatma, S, Huang, R.H. | | 登録日 | 2021-09-22 | | 公開日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | | 主引用文献 | Sequential rescue and repair of stalled and damaged ribosome by bacterial PrfH and RtcB.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7UG7
 | | 70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Rundlet, E.J, Wieland, M, Holm, M, Koller, T.O, Blanchard, S.C, Wilson, D.N. | | 登録日 | 2022-03-24 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | | 主引用文献 | The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
6YSS
 | | Structure of the P+9 ArfB-ribosome complex in the post-hydrolysis state | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V. | | 登録日 | 2020-04-23 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
|
|
7NWT
 | | Initiated 70S ribosome in complex with 2A protein from encephalomyocarditis virus (EMCV) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Hill, C.H, Napthine, S, Pekarek, L, Kibe, A, Firth, A.E, Graham, S.C, Caliskan, N, Brierley, I. | | 登録日 | 2021-03-17 | | 公開日 | 2021-12-15 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Structural and molecular basis for Cardiovirus 2A protein as a viral gene expression switch
Nat Commun, 12, 2021
|
|
6XZA
 | | E. coli 70S ribosome in complex with dirithromycin, and deacylated tRNA(iMet) (focused classification). | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L. | | 登録日 | 2020-02-03 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome.
Rna, 26, 2020
|
|
7N2C
 | | Elongating 70S ribosome complex in a fusidic acid-stalled intermediate state of translocation bound to EF-G(GDP) (INT2) | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, K.S, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Structural basis of early translocation events on the ribosome.
Nature, 595, 2021
|
|
8P16
 | | E167K RF2 on E. coli 70S release complex with UGG (Structure I) | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. | | 登録日 | 2023-05-11 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of
RF1 in bacteria
To Be Published
|
|
8P18
 | | E167K RF2 on E. coli 70S release complex with UGG (Structure III) | | 分子名称: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | 著者 | Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. | | 登録日 | 2023-05-11 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of
RF1 in bacteria
To Be Published
|
|
8P17
 | | E167K RF2 on E. coli 70S release complex with UGG (Structure II) | | 分子名称: | 1,4-DIAMINOBUTANE, 16S RNA, 23S rRNA, ... | | 著者 | Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. | | 登録日 | 2023-05-11 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of
RF1 in bacteria
To Be Published
|
|
4U27
 | | Crystal structure of the E. coli ribosome bound to flopristin and linopristin. | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | | 登録日 | 2014-07-16 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
|
|
4U26
 | | Crystal structure of the E. coli ribosome bound to dalfopristin and quinupristin. | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | | 登録日 | 2014-07-16 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
|
|
7M5D
 | |
5J5B
 | | Structure of the WT E coli ribosome bound to tetracycline | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | | 著者 | Cocozaki, A, Ferguson, A. | | 登録日 | 2016-04-01 | | 公開日 | 2016-07-27 | | 最終更新日 | 2018-08-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
6U48
 | | E. coli 50S with phazolicin (PHZ) bound in exit tunnel | | 分子名称: | 23S rRNA, 50S ribosomal protein bL17, 50S ribosomal protein bL19, ... | | 著者 | Watson, Z.L, Cate, J.H.D, Polikanov, Y.S, Severinov, K. | | 登録日 | 2019-08-23 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | | 主引用文献 | Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition.
Nat Commun, 10, 2019
|
|
4V9O
 | |
4V9P
 | |
7ST2
 | |
