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PDB: 7 件
7OPB
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BU of 7opb by Molmil
IL7R in complex with an antagonist
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ...
著者Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N.
登録日2021-05-31
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.144 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
3UP1
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BU of 3up1 by Molmil
Crystal structure of the unliganded human interleukin-7 receptor extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者McElroy, C.A, Holland, P.J, Walsh, S.T.R.
登録日2011-11-17
公開日2012-02-08
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural reorganization of the interleukin-7 signaling complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
5J11
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BU of 5j11 by Molmil
Structure of human TSLP in complex with TSLPR and IL-7Ralpha
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor-like factor 2, Interleukin-7 receptor subunit alpha, ...
著者Verstraete, K, Savvides, S.N.
登録日2016-03-28
公開日2017-04-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma.
Nat Commun, 8, 2017
3DI2
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BU of 3di2 by Molmil
Crystal structure of the complex of human interleukin-7 with unglycosylated human interleukin-7 receptor alpha ectodomain
分子名称: Interleukin-7, Interleukin-7 receptor subunit alpha, PENTAETHYLENE GLYCOL
著者McElroy, C.A, Dohm, J.A, Walsh, S.T.R.
登録日2008-06-19
公開日2009-01-27
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Biophysical Studies of the Human IL-7/IL-7Ralpha Complex.
Structure, 17, 2009
6P67
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BU of 6p67 by Molmil
Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IL-7R 2B8 Fab heavy chain, ...
著者Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
登録日2019-06-03
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
6P50
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BU of 6p50 by Molmil
Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha Fab 4A10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-7 receptor subunit alpha, anti-IL-7R 4A10 Fab heavy chain, ...
著者Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
登録日2019-05-29
公開日2019-09-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
3DI3
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BU of 3di3 by Molmil
Crystal structure of the complex of human interleukin-7 with glycosylated human interleukin-7 receptor alpha ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-7, Interleukin-7 receptor subunit alpha
著者McElroy, C.A, Dohm, J.A, Walsh, S.T.R.
登録日2008-06-19
公開日2009-01-27
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and Biophysical Studies of the Human IL-7/IL-7Ralpha Complex.
Structure, 17, 2009

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件を2024-07-24に公開中

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