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PDB: 280 件

1M18
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LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
分子名称: Histone H2A.1, Histone H2B.1, Histone H3.2, ...
著者Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K.
登録日2002-06-18
公開日2003-02-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.Mol.Biol., 326, 2003
3LZ0
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Crystal Structure of Nucleosome Core Particle Composed of the Widom 601 DNA Sequence (orientation 1)
分子名称: CHLORIDE ION, DNA (145-MER), Histone H2A, ...
著者Vasudevan, D, Chua, E.Y.D, Davey, C.A.
登録日2010-03-01
公開日2010-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of nucleosome core particles containing the '601' strong positioning sequence
J.Mol.Biol., 403, 2010
3LZ1
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Crystal Structure of Nucleosome Core Particle Composed of the Widom 601 DNA Sequence (orientation 2)
分子名称: CHLORIDE ION, DNA (145-MER), Histone H2A, ...
著者Vasudevan, D, Chua, E.Y.D, Davey, C.A.
登録日2010-03-01
公開日2010-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of nucleosome core particles containing the '601' strong positioning sequence
J.Mol.Biol., 403, 2010
3REH
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2.5 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 145 bp Alpha-Satellite DNA (NCP145)
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Wu, B, Davey, C.A.
登録日2011-04-04
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
3MNN
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BU of 3mnn by Molmil
A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core
分子名称: 1,3,5-triaza-7-phosphatricyclo[3.3.1.1~3,7~]decane, 1-methyl-4-(1-methylethyl)benzene, DNA (145-MER), ...
著者Ong, M.S, Davey, C.A.
登録日2010-04-22
公開日2011-04-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core
Chemistry, 17, 2011
4Z66
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Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
登録日2015-04-03
公開日2015-10-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015
7OHC
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BU of 7ohc by Molmil
Cryo-EM structure of nucleosome core particle composed of the Widom 601 DNA sequence
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Wang, H, Cramer, P.
登録日2021-05-10
公開日2021-07-28
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
6ZHX
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Cryo-EM structure of the regulatory linker of ALC1 bound to the nucleosome's acidic patch: nucleosome class.
分子名称: Chromodomain-helicase-DNA-binding protein 1-like, DNA (145-MER) Widom 601 sequence, Histone H2A type 1, ...
著者Bacic, L, Gaullier, G, Croll, T.I, Deindl, S.
登録日2020-06-24
公開日2020-12-23
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Cell Rep, 33, 2020
6GYT
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Transcription factor dimerization activates the p300 acetyltransferase
分子名称: Histone H4, Histone acetyltransferase p300, ZINC ION
著者Panne, D, Ortega, E.
登録日2018-07-01
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Transcription factor dimerization activates the p300 acetyltransferase.
Nature, 562, 2018
3REJ
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BU of 3rej by Molmil
2.55 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b)
分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Wu, B, Davey, C.A.
登録日2011-04-04
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
8CZE
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Structure of a Xenopus Nucleosome with Widom 601 DNA
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D.
登録日2022-05-24
公開日2023-06-07
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Chromatin binding by HORMAD proteins regulates meiotic recombination initiation.
Embo J., 43, 2024
4J8V
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BU of 4j8v by Molmil
X-ray structure of NCP145 with bound chlorido(eta-6-p-cymene)(N-phenyl-2-pyridinecarbothioamide)ruthenium(II)
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Adhireksan, Z, Davey, C.A.
登録日2013-02-15
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
8T9F
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BU of 8t9f by Molmil
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1
分子名称: DNA (122-MER), Histone H2A.Z, Histone H2B 1.1, ...
著者Abini-Agbomson, S, Armache, K.-J.
登録日2023-06-23
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1.
Mol.Cell, 83, 2023
4WU9
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BU of 4wu9 by Molmil
Structure of cisPtNAP-NCP145
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Chua, E.Y.D, Davey, G.E, Chin, C.F, Droge, P, Ang, W.H, Davey, C.A.
登録日2014-10-31
公開日2015-09-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Stereochemical control of nucleosome targeting by platinum-intercalator antitumor agents.
Nucleic Acids Res., 43, 2015
3REK
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BU of 3rek by Molmil
2.6 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Oxaliplatin
分子名称: DNA (146-MER), Histone H2A type1, Histone H2B 1.1, ...
著者Wu, B, Davey, C.A.
登録日2011-04-04
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
7SWY
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BU of 7swy by Molmil
2.6 A structure of a 40-601[TA-rich+1]-40 nucleosome
分子名称: DNA Guide Strand, DNA Tracking Strand, Histone H2A, ...
著者Nodelman, I.M, Bowman, G.D, Armache, J.-P.
登録日2021-11-21
公開日2022-03-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state.
Nat.Struct.Mol.Biol., 29, 2022
1KX4
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BU of 1kx4 by Molmil
X-Ray Structure of the Nucleosome Core Particle, NCP146b, at 2.6 A Resolution
分子名称: CHLORIDE ION, DNA (5'(ATCTCCAAATATCCCTTGCGGATCGTAGAAAAAGTGTGTCAAACTGCGCTATCAAAGGGAAACTTCAACTGAATTCAGTTGAAGTTTCCCTTTGATAGCGCAGTTTGACACACTTTTTCTACGATCCGCAAGGGATATTTGGAGAT)3'), MANGANESE (II) ION, ...
著者Davey, C.A, Sargent, D.F, Luger, K, Maeder, A.W, Richmond, T.J.
登録日2002-01-31
公開日2002-12-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9 A Resolution
J.Mol.Biol., 319, 2002
5CP6
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Nucleosome Core Particle with Adducts from the Anticancer Compound, [(eta6-5,8,9,10-tetrahydroanthracene)Ru(ethylenediamine)Cl][PF6]
分子名称: (ethane6-5,8,9,10-tetrahydroanthracene)Ru(II)(ethylene-diamine)Cl, DNA (145-MER), Histone H2A, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2015-07-21
公開日2016-06-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode.
Angew.Chem.Int.Ed.Engl., 55, 2016
5XF6
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BU of 5xf6 by Molmil
Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having an ethylenediamine linker
分子名称: DNA (145-MER), ETHANE-1,2-DIAMINE, Histone H2A, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
5F99
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X-ray Structure of the MMTV-A Nucleosome Core Particle
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A type 1, ...
著者Frouws, T.D, Richmond, T.J.
登録日2015-12-09
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献X-ray structure of the MMTV-A nucleosome core.
Proc.Natl.Acad.Sci.USA, 113, 2016
3MGQ
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BU of 3mgq by Molmil
Binding of Nickel ions to the Nucleosome Core Particle
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Mohideen, K, Muhammad, R, Davey, C.A.
登録日2010-04-07
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
2NZD
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Nucleosome core particle containing 145 bp of DNA
分子名称: DNA (145-MER), Histone H2B, Histone H3, ...
著者Ong, M.S, Richmond, T.J, Davey, C.A.
登録日2006-11-23
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献DNA stretching and extreme kinking in the nucleosome core
J.Mol.Biol., 368, 2007
3REI
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BU of 3rei by Molmil
2.65 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 145 bp Alpha-Satellite DNA (NCP145) Derivatized with Triamminechloroplatinum(II) Chloride
分子名称: DNA (145-MER), Histone H2A type1, Histone H2B 1.1, ...
著者Wu, B, Davey, C.A.
登録日2011-04-04
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
1M1A
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BU of 1m1a by Molmil
LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA
分子名称: 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, 4-AMINO-(1-METHYLPYRROLE)-2-CARBOXYLIC ACID, ...
著者Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K.
登録日2002-06-18
公開日2003-02-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
J.MOL.BIOL., 326, 2003
8PEO
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H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex
分子名称: (2R)-2-amino-3-(2-dimethylaminoethylsulfanyl)propanoic acid, Histone H2A, Histone H2B 1.1, ...
著者Koutna, E, Kouba, T, Veverka, V.
登録日2023-06-14
公開日2023-08-16
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023

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