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PDB: 465 件

5XF3
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Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,R-configuration)
分子名称: (1R,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
6V2H
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Crystal structure of CDYL2 in complex with H3tK27me3
分子名称: Chromodomain Y-like protein 2, H3tK27me3, NICKEL (II) ION, ...
著者Dong, C, Tempel, W, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2019-11-22
公開日2019-12-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for the Binding Selectivity of Human CDY Chromodomains.
Cell Chem Biol, 27, 2020
5B2J
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Human nucleosome containing CpG methylated DNA
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Fujii, Y, Wakamori, M, Umehara, T, Yokoyama, S.
登録日2016-01-18
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation.
Febs Open Bio, 6, 2016
6LE9
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BU of 6le9 by Molmil
The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties
分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Histone H3.1, ...
著者Soman, A, Liew, C.W, Teo, H.L, Berezhnoy, N, Korolev, N, Rhodes, D, Nordenskiold, L.
登録日2019-11-24
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The human telomeric nucleosome displays distinct structural and dynamic properties.
Nucleic Acids Res., 48, 2020
5HJC
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BU of 5hjc by Molmil
BRD3 second bromodomain in complex with histone H3 acetylation at K18
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 3, CHLORIDE ION, ...
著者Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
登録日2016-01-13
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
6L9H
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BU of 6l9h by Molmil
The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties
分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Histone H3.1, ...
著者Soman, A, Liew, C.W, Teo, H.L, Berezhnoy, N, Korolev, N, Rhodes, D, Nordenskiold, L.
登録日2019-11-10
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The human telomeric nucleosome displays distinct structural and dynamic properties.
Nucleic Acids Res., 48, 2020
5VGE
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BU of 5vge by Molmil
Crystal structure of HLA-C*07:02 in complex with RYR peptide
分子名称: ARG-TYR-ARG-PRO-GLY-THR-VAL-ALA-LEU, Beta-2-microglobulin, ZINC ION, ...
著者Mobbs, J.I, Vivian, J.P, Gras, S, Rossjohn, J.
登録日2017-04-11
公開日2017-06-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and regulatory diversity shape HLA-C protein expression levels.
Nat Commun, 8, 2017
3MP1
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BU of 3mp1 by Molmil
Complex structure of Sgf29 and trimethylated H3K4
分子名称: ACETATE ION, H3K4me3 peptide, Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, ...
著者Li, J, Ruan, J, Wu, M, Xue, X, Zang, J.
登録日2010-04-24
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
6V2K
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The nucleosome structure after H2A-H2B exchange
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A, ...
著者Arimura, Y, Hirano, R, Kurumizaka, H.
登録日2019-11-24
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome.
Commun Biol, 4, 2021
2C1J
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BU of 2c1j by Molmil
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3
分子名称: 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE
著者Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C.
登録日2005-09-15
公開日2005-11-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
Mol.Cell, 20, 2005
3UII
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BU of 3uii by Molmil
crystal structure of human Survivin in complex with H3(1-10) peptide
分子名称: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3(1-10) peptide
著者Du, J, Patel, D.J.
登録日2011-11-04
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20, 2012
8Q36
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BU of 8q36 by Molmil
Structure of Nucleosome Core with a Bound Metallopeptide Conjugate (Foamy Virus GAG Peptide-Au[I] Compound)
分子名称: DNA (145-MER), GAG structural protein, Histone H2A type 1-B/E, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-03
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
3UEE
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BU of 3uee by Molmil
Crystal structure of human Survivin K62A mutant bound to N-terminal histone H3
分子名称: Baculoviral IAP repeat-containing protein 5, N-terminal fragment of histone H3, ZINC ION
著者Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W.
登録日2011-10-30
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres.
Mol.Biol.Cell, 23, 2012
5DAH
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BU of 5dah by Molmil
Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide
分子名称: Histone H3 peptide, Protein AF-10, SULFATE ION, ...
著者Chen, S, Patel, D.J.
登録日2015-08-19
公開日2015-10-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.611 Å)
主引用文献The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
5CPK
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BU of 5cpk by Molmil
Nucleosome containing methylated Sat2L DNA
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Osakabe, A, Arimura, Y, Adachi, F, Maehara, K, Ohkawa, Y, Kurumizaka, H.
登録日2015-07-21
公開日2015-10-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.632 Å)
主引用文献Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA.
Open Biology, 5, 2015
8EVI
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BU of 8evi by Molmil
CX3CR1 nucleosome and PU.1 complex containing disulfide bond mutations
分子名称: DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2022-10-20
公開日2023-11-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
8JL9
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BU of 8jl9 by Molmil
Cryo-EM structure of the human nucleosome with scFv
分子名称: DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-02
公開日2023-10-04
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
2B2V
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BU of 2b2v by Molmil
Crystal structure analysis of human CHD1 chromodomains 1 and 2 bound to histone H3 resi 1-15 MeK4
分子名称: Chromodomain-helicase-DNA-binding protein 1, Histone H3
著者Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
登録日2005-09-19
公開日2005-12-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
8YBK
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Cryo-EM structure of the human nucleosome containing the H3.1 E97K mutant
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2024-02-14
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K.
Genes Cells, 2024
7LBQ
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BU of 7lbq by Molmil
Crystal structure of human Survivin bound to histone H3 T3phK4me2 peptide
分子名称: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3 T3phK4me2 peptide
著者Niedzialkowska, E, Minor, W, Stukenberg, P.T.
登録日2021-01-08
公開日2022-01-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Tip60 acetylation of histone H3K4 temporally controls chromosome passenger complex localization.
Mol.Biol.Cell, 33, 2022
5X60
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Crystal structure of LSD1-CoREST in complex with peptide 9
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ...
著者Kikuchi, M, Amano, Y, Sato, S, Yokoyama, S, Umezawa, N, Higuchi, T, Umehara, T.
登録日2017-02-20
公開日2017-04-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.
Bioorg. Med. Chem., 25, 2017
5XNV
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Crystal structure of YEATS2 YEATS bound to H3K27ac peptide
分子名称: ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, CHLORIDE ION, ...
著者Li, H.T, Guan, H.P, Zhao, D.
登録日2017-05-24
公開日2017-11-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.696 Å)
主引用文献YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Nat Commun, 8, 2017
8YTI
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BU of 8yti by Molmil
Crystal Structure of Nucleosome-H1x Linker Histone Assembly (sticky-169a DNA fragment)
分子名称: CALCIUM ION, CHLORIDE ION, DNA (169-MER), ...
著者Adhireksan, Z, Qiuye, B, Padavattan, S, Davey, C.A.
登録日2024-03-26
公開日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Linker Histones Associate Heterogeneously with Nucleosomes in the Condensed State
To Be Published
7U0J
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Structure of 162bp LIN28b nucleosome
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2022-02-18
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
7LBK
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BU of 7lbk by Molmil
Crystal structure of human Survivin bound to histone H3 T3phK4me3 peptide
分子名称: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3 T3phK4me3 peptide
著者Niedzialkowska, E, Minor, W, Stukenberg, P.T.
登録日2021-01-08
公開日2022-01-12
最終更新日2022-08-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Tip60 acetylation of histone H3K4 temporally controls chromosome passenger complex localization.
Mol.Biol.Cell, 33, 2022

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