5XF3
 
 | | Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,R-configuration) | | 分子名称: | (1R,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ... | | 著者 | Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. | | 登録日 | 2017-04-07 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
|
|
6L9H
 | | The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties | | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-K, Histone H3.1, ... | | 著者 | Soman, A, Liew, C.W, Teo, H.L, Berezhnoy, N, Korolev, N, Rhodes, D, Nordenskiold, L. | | 登録日 | 2019-11-10 | | 公開日 | 2020-04-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The human telomeric nucleosome displays distinct structural and dynamic properties.
Nucleic Acids Res., 48, 2020
|
|
2C1J
 | | Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3 | | 分子名称: | 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE | | 著者 | Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C. | | 登録日 | 2005-09-15 | | 公開日 | 2005-11-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3.
Mol.Cell, 20, 2005
|
|
6V2K
 | | The nucleosome structure after H2A-H2B exchange | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A, ... | | 著者 | Arimura, Y, Hirano, R, Kurumizaka, H. | | 登録日 | 2019-11-24 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome.
Commun Biol, 4, 2021
|
|
5H6R
 | | Crystal structure of LSD1-CoREST in complex with peptide 13 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... | | 著者 | Kkuchi, M, Amano, Y, Sato, S, Yokoyama, S, Umezawa, N, Higuchi, T, Umehara, T. | | 登録日 | 2016-11-14 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.
Bioorg. Med. Chem., 25, 2017
|
|
5HJC
 | | BRD3 second bromodomain in complex with histone H3 acetylation at K18 | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 3, CHLORIDE ION, ... | | 著者 | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | | 登録日 | 2016-01-13 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
|
|
3MP1
 | | Complex structure of Sgf29 and trimethylated H3K4 | | 分子名称: | ACETATE ION, H3K4me3 peptide, Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, ... | | 著者 | Li, J, Ruan, J, Wu, M, Xue, X, Zang, J. | | 登録日 | 2010-04-24 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
|
|
5B2J
 | | Human nucleosome containing CpG methylated DNA | | 分子名称: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Fujii, Y, Wakamori, M, Umehara, T, Yokoyama, S. | | 登録日 | 2016-01-18 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation.
Febs Open Bio, 6, 2016
|
|
8Q36
 | | Structure of Nucleosome Core with a Bound Metallopeptide Conjugate (Foamy Virus GAG Peptide-Au[I] Compound) | | 分子名称: | DNA (145-MER), GAG structural protein, Histone H2A type 1-B/E, ... | | 著者 | De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A. | | 登録日 | 2023-08-03 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | | 主引用文献 | Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
|
|
3UEE
 | | Crystal structure of human Survivin K62A mutant bound to N-terminal histone H3 | | 分子名称: | Baculoviral IAP repeat-containing protein 5, N-terminal fragment of histone H3, ZINC ION | | 著者 | Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W. | | 登録日 | 2011-10-30 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres.
Mol.Biol.Cell, 23, 2012
|
|
5DAH
 | |
5CPK
 | | Nucleosome containing methylated Sat2L DNA | | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Osakabe, A, Arimura, Y, Adachi, F, Maehara, K, Ohkawa, Y, Kurumizaka, H. | | 登録日 | 2015-07-21 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.632 Å) | | 主引用文献 | Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA.
Open Biology, 5, 2015
|
|
8EVI
 | | CX3CR1 nucleosome and PU.1 complex containing disulfide bond mutations | | 分子名称: | DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Lian, T, Guan, R, Bai, Y. | | 登録日 | 2022-10-20 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | | 主引用文献 | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8JL9
 | | Cryo-EM structure of the human nucleosome with scFv | | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-06-02 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
|
|
2B2V
 | | Crystal structure analysis of human CHD1 chromodomains 1 and 2 bound to histone H3 resi 1-15 MeK4 | | 分子名称: | Chromodomain-helicase-DNA-binding protein 1, Histone H3 | | 著者 | Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S. | | 登録日 | 2005-09-19 | | 公開日 | 2005-12-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
|
|
5X60
 | | Crystal structure of LSD1-CoREST in complex with peptide 9 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... | | 著者 | Kikuchi, M, Amano, Y, Sato, S, Yokoyama, S, Umezawa, N, Higuchi, T, Umehara, T. | | 登録日 | 2017-02-20 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.
Bioorg. Med. Chem., 25, 2017
|
|
7LBQ
 | |
5XNV
 | | Crystal structure of YEATS2 YEATS bound to H3K27ac peptide | | 分子名称: | ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, CHLORIDE ION, ... | | 著者 | Li, H.T, Guan, H.P, Zhao, D. | | 登録日 | 2017-05-24 | | 公開日 | 2017-11-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.696 Å) | | 主引用文献 | YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Nat Commun, 8, 2017
|
|
7U0J
 | | Structure of 162bp LIN28b nucleosome | | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Lian, T, Guan, R, Bai, Y. | | 登録日 | 2022-02-18 | | 公開日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
|
|
8YTI
 | | Crystal Structure of Nucleosome-H1x Linker Histone Assembly (sticky-169a DNA fragment) | | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (169-MER), ... | | 著者 | Adhireksan, Z, Qiuye, B, Padavattan, S, Davey, C.A. | | 登録日 | 2024-03-26 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Linker Histones Associate Heterogeneously with Nucleosomes in the Condensed State
To Be Published
|
|
8OOP
 | | CryoEM Structure INO80core Hexasome complex composite model state2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ... | | 著者 | Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. | | 登録日 | 2023-04-05 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
|
|
5GTC
 | | Crystal structure of complex between DMAP-SH conjugated with a Kaposi's sarcoma herpesvirus LANA peptide (5-15) and nucleosome core particle | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | | 著者 | Arimura, Y, Kato, D, Suto, H, Kurumizaka, H, Kawashima, S.A, Yamatsugu, K, Kanai, M. | | 登録日 | 2016-08-19 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Synthetic Posttranslational Modifications: Chemical Catalyst-Driven Regioselective Histone Acylation of Native Chromatin.
J. Am. Chem. Soc., 139, 2017
|
|
4FT4
 | |
3AZL
 | | Crystal Structure of Human Nucleosome Core Particle Containing H4K77Q mutation | | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | | 著者 | Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2011-05-25 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
|
|
3AZF
 | | Crystal Structure of Human Nucleosome Core Particle Containing H3K79Q mutation | | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | | 著者 | Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2011-05-25 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
|
|
