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PDB: 36 件
7SG5
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BU of 7sg5 by Molmil
Structure of PfCSP peptide 21 with antibody CIS43_Var2
分子名称: CIS43_Var2 Fab Heavy chain, CIS43_Var2 Fab Light chain, GLYCEROL, ...
著者Tripathi, P, Kwong, P.D.
登録日2021-10-05
公開日2022-06-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Highly protective antimalarial antibodies via precision library generation and yeast display screening.
J.Exp.Med., 219, 2022
7SG6
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BU of 7sg6 by Molmil
Structure of PfCSP peptide 21 with antibody CIS43_Var10
分子名称: CIS43_Var10 Fab Heavy chain, CIS43_Var10 Fab Light chain, GLYCEROL, ...
著者Tripathi, P, Kwong, P.D.
登録日2021-10-05
公開日2022-06-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Highly protective antimalarial antibodies via precision library generation and yeast display screening.
J.Exp.Med., 219, 2022
6PBV
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BU of 6pbv by Molmil
Crystal structure of Fab668 complex
分子名称: 1,2-ETHANEDIOL, Fab668 heavy chain, Fab668 light chain, ...
著者Oyen, D, Wilson, I.A.
登録日2019-06-14
公開日2020-03-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.566 Å)
主引用文献Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
3VDJ
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BU of 3vdj by Molmil
Crystal structure of circumsporozoite protein aTSR domain, R32 native form
分子名称: Circumsporozoite (CS) protein
著者Doud, M.B, Koksal, A.C, Mi, L.Z, Song, G, Lu, C, Springer, T.A.
登録日2012-01-05
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
7RXP
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BU of 7rxp by Molmil
Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab1512 heavy chain, Fab1512 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.761 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
6BQB
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BU of 6bqb by Molmil
MGG4 Fab in complex with peptide
分子名称: GLYCEROL, MGG4 Fab heavy chain, MGG4 Fab light chain, ...
著者Oyen, D, Tan, J, Lanzavecchia, A, Wilson, I.A.
登録日2017-11-27
公開日2018-03-07
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (1.769 Å)
主引用文献A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.
Nat. Med., 24, 2018
7LKB
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BU of 7lkb by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.127
分子名称: Circumsporozoite protein, SULFATE ION, m42.127 Fab heavy Chain, ...
著者Xu, K, Kwong, P.D.
登録日2021-02-02
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7UFO
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BU of 7ufo by Molmil
Structure of PfCSP peptide 21 with antibody P3-42
分子名称: GLYCEROL, P3-42 Fab Heavy chain, P3-42 Fab Light chain, ...
著者Tripathi, P, Kwong, P.D.
登録日2022-03-23
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of PfCSP peptide 21 with antibody P3-42
To Be Published
7RXL
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BU of 7rxl by Molmil
Fab1488 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab1488 heavy chain, Fab1488 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.823 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
3VDK
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BU of 3vdk by Molmil
Crystal structure of circumsporozoite protein aTSR domain, R32 platinum-bound form
分子名称: Circumsporozoite (CS) protein, PLATINUM (II) ION
著者Doud, M.B, Koksal, A.C, Mi, L.Z, Song, G, Lu, C, Springer, T.A.
登録日2012-01-05
公開日2012-05-09
最終更新日2012-05-30
実験手法X-RAY DIFFRACTION (1.847 Å)
主引用文献Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
7RQQ
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BU of 7rqq by Molmil
Structure of chimeric antibody F10heavy_L9light with PfCSP peptide NANPNVDP
分子名称: 1,2-ETHANEDIOL, F10 Heavy Chain, L9 Kappa Chain, ...
著者Hurlburt, N.K, Pancera, M.
登録日2021-08-06
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
7LKG
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Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.151
分子名称: Circumsporozoite protein, m43.151 Fab Heavy Chain, m43.151 Fab Light chain
著者Xu, K, Kwong, P.D.
登録日2021-02-02
公開日2021-12-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
3VDL
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BU of 3vdl by Molmil
Crystal structure of circumsporozoite protein aTSR domain, P43212 form
分子名称: Circumsporozoite (CS) protein
著者Doud, M.B, Koksal, A.C, Mi, L.Z, Song, G, Lu, C, Springer, T.A.
登録日2012-01-05
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
6PBW
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BU of 6pbw by Molmil
Crystal structure of Fab667 complex
分子名称: Fab667 heavy chain, Fab667 light chain, GLYCEROL, ...
著者Oyen, D, Wilson, I.A.
登録日2019-06-14
公開日2020-03-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.058 Å)
主引用文献Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
7RXI
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BU of 7rxi by Molmil
Fab234 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab234 heavy chain, Fab234 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7UYM
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BU of 7uym by Molmil
850 Fab in complex with NANPNANPNANP peptide
分子名称: 850 Fab Heavy Chain, 850 Fab Light Chain, Circumsporozoite protein, ...
著者Kucharska, I, Prieto, K, Julien, J.P.
登録日2022-05-06
公開日2022-11-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
Plos Pathog., 18, 2022
7UFN
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BU of 7ufn by Molmil
Structure of PfCSP peptide 21 with antibody P3-21
分子名称: P3-21 Fab Heavy chain, P3-21 Fab Light chain, PfCSP peptide 21, ...
著者Tripathi, P, Kwong, P.D.
登録日2022-03-22
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of PfCSP peptide 21 with antibody P3-21
To Be Published
7RQR
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BU of 7rqr by Molmil
Structure of chimeric antibody L9heavy_F10light with PfCSP peptide NANPNVDP
分子名称: 1,2-ETHANEDIOL, F10 Kappa Chain, L9 Heavy Chain, ...
著者Hurlburt, N.K, Pancera, M.
登録日2021-08-06
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
7UFQ
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BU of 7ufq by Molmil
Structure of PfCSP peptide 21 with antibody P3-43
分子名称: GLYCEROL, P3-43 Fab Heavy chain, P3-43 Fab Light chain, ...
著者Tripathi, P, Kwong, P.D.
登録日2022-03-23
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of PfCSP peptide 21 with antibody P3-43
To Be Published
7RXJ
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BU of 7rxj by Molmil
Fab236 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab236 heavy chain, Fab236 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.345 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
8FG0
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BU of 8fg0 by Molmil
Crystal structure of the 3764 Fab in complex with the C-terminal PfCSP linker, PfCSP281-294.
分子名称: 3764 Fab Heavy chain, 3764 Fab Light chain, Circumsporozoite protein
著者Burn Aschner, C, Julien, J.P.
登録日2022-12-11
公開日2023-05-10
最終更新日2023-06-14
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies.
Embo Mol Med, 15, 2023
8DZ3
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BU of 8dz3 by Molmil
Cryo-EM structure of 337 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
分子名称: 337 Fab heavy chain, 337 Fab light chain, Circumsporozoite protein
著者Martin, G.M, Ward, A.B.
登録日2022-08-06
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
7S0X
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BU of 7s0x by Molmil
Fab352 in complex with the C-terminal alphaTSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab352 heavy chain, Fab352 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-31
公開日2022-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
8DYX
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BU of 8dyx by Molmil
Cryo-EM structure of 311 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
分子名称: 311 heavy chain, 311 light chain, Circumsporozoite protein
著者Martin, G.M, Ward, A.B.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DZ4
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BU of 8dz4 by Molmil
Cryo-EM structure of 356 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
分子名称: 356 Fab heavy chain, 356 Fab light chain, Circumsporozoite protein
著者Martin, G.M, Ward, A.B.
登録日2022-08-06
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023

 

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