1XGJ
 
 | | AmpC beta-lactamase in complex with 3-(4-carboxy-2-hydroxy-phenylsulfamoyl)-thiophene-2-carboxylic acid | | 分子名称: | 3-{[(4-CARBOXY-2-HYDROXYANILINE]SULFONYL}THIOPHENE-2-CARBOXYLIC ACID, Beta-lactamase | | 著者 | Tondi, D, Morandi, F, Bonnet, R, Costi, M.P, Shoichet, B.K. | | 登録日 | 2004-09-17 | | 公開日 | 2005-05-03 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structure-based optimization of a non-beta-lactam lead results in inhibitors that do not up-regulate beta-lactamase expression in cell culture.
J.Am.Chem.Soc., 127, 2005
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1XGI
 | | AmpC beta-lactamase in complex with 3-(3-nitro-phenylsulfamoyl)-thiophene-2-carboxylic acid | | 分子名称: | 3-{[(3-NITROANILINE]SULFONYL}THIOPHENE-2-CARBOXYLIC ACID, Beta-lactamase | | 著者 | Tondi, D, Morandi, F, Bonnet, R, Costi, M.P, Shoichet, B.K. | | 登録日 | 2004-09-17 | | 公開日 | 2005-05-03 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structure-based optimization of a non-beta-lactam lead results in inhibitors that do not up-regulate beta-lactamase expression in cell culture.
J.Am.Chem.Soc., 127, 2005
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1KJL
 | | High Resolution X-Ray Structure of Human Galectin-3 in complex with LacNAc | | 分子名称: | BROMIDE ION, CHLORIDE ION, Galectin-3, ... | | 著者 | Sorme, P, Arnoux, P, Kahl-Knutsson, B, Leffler, H, Rini, J.M, Nilsson, U.J. | | 登録日 | 2001-12-04 | | 公開日 | 2005-04-12 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural and thermodynamic studies on cation-Pi interactions in lectin-ligand complexes: high-affinity galectin-3 inhibitors through fine-tuning of an arginine-arene interaction.
J.Am.Chem.Soc., 127, 2005
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1U9F
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1U74
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1U9E
 | | CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-397 | | 分子名称: | 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL, Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1 | | 著者 | Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C. | | 登録日 | 2004-08-09 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-Based Design Of Estrogen Receptor-beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
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1U75
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1U9H
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1U9G
 | | Heterocyclic Peptide Backbone Modification in GCN4-pLI Based Coiled Coils: Replacement of K(8)L(9) | | 分子名称: | General control protein GCN4, SULFATE ION | | 著者 | Horne, W.S, Yadav, M.K, Stout, C.D, Ghadiri, M.R. | | 登録日 | 2004-08-09 | | 公開日 | 2004-11-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Heterocyclic peptide backbone modifications in an alpha-helical coiled coil.
J.Am.Chem.Soc., 126, 2004
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1U21
 | | transthyretin with tethered inhibitor on one monomer. | | 分子名称: | 2-[(3,5-DICHLORO-4-TRIOXIDANYLPHENYL)AMINO]BENZOIC ACID, Transthyretin | | 著者 | Wiseman, R.L, Johnson, S.M, Kelker, M.S, Foss, T, Wilson, I.A, Kelly, J.W. | | 登録日 | 2004-07-16 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Kinetic stabilization of an oligomeric protein by a single ligand binding event
J.Am.Chem.Soc., 127, 2005
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1KJR
 | | Crystal Structure of the human galectin-3 CRD in complex with a 3'-derivative of N-Acetyllactosamine | | 分子名称: | 2,3,5,6-TETRAFLUORO-4-METHOXY-BENZAMIDE, CHLORIDE ION, Galectin-3, ... | | 著者 | Sorme, P, Arnoux, P, Kahl-Knutsson, B, Leffler, H, Rini, J.M, Nilsson, U.J. | | 登録日 | 2001-12-05 | | 公開日 | 2005-04-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural and thermodynamic studies on cation-Pi interactions in lectin-ligand complexes: high-affinity galectin-3 inhibitors through fine-tuning of an arginine-arene interaction.
J.Am.Chem.Soc., 127, 2005
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1YM1
 | | X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with a boronic acid inhibitor (SM2) | | 分子名称: | (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID, PHOSPHATE ION, beta-lactamase CTX-M-9a | | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-20 | | 公開日 | 2005-04-26 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases.
J.Am.Chem.Soc., 127, 2005
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1PPV
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1S2R
 | | A High Resolution Crystal Structure of [d(CGCAAATTTGCG)]2 | | 分子名称: | 5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3', SPERMINE | | 著者 | Woods, K.K, Maehigashi, T, Howerton, S.B, Tannenbaum, S, Williams, L.D. | | 登録日 | 2004-01-09 | | 公開日 | 2005-01-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | High-resolution structure of an extended A-tract: [d(CGCAAATTTGCG)]2.
J.Am.Chem.Soc., 126, 2004
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1S9B
 | | Crystal Structure Analysis of the B-DNA GAATTCG | | 分子名称: | 5'-D(*GP*AP*AP*TP*TP*CP*G)-3', NICKEL (II) ION | | 著者 | Valls, N, Uson, I, Gouyette, C, Subirana, J.A. | | 登録日 | 2004-02-04 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | A cubic arrangement of DNA double helices based on nickel-guanine interactions
J.Am.Chem.Soc., 126, 2004
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1T1R
 | | Crystal Structure of the Reductoisomerase Complexed with a Bisphosphonate | | 分子名称: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, SULFATE ION, [(ISOQUINOLIN-1-YLAMINO)-PHOSPHONO-METHYL]-PHOSPHONIC ACID | | 著者 | Yajima, S, Hara, K, Sanders, J.M, Yin, F, Ohsawa, K, Wiesner, J, Jomaa, H, Oldfield, E. | | 登録日 | 2004-04-17 | | 公開日 | 2004-09-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystallographic Structures of Two Bisphosphonate:1-Deoxyxylulose-5-Phosphate Reductoisomerase Complexes
J.Am.Chem.Soc., 126, 2004
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1T6W
 | | RATIONAL DESIGN OF A CALCIUM-BINDING ADHESION PROTEIN NMR, 20 STRUCTURES | | 分子名称: | CALCIUM ION, hypothetical protein XP_346638 | | 著者 | Yang, W, Wilkins, A.L, Ye, Y, Liu, Z.-R, Urbauer, J.L, Kearney, A, van der Merwe, P.A, Yang, J.J. | | 登録日 | 2004-05-07 | | 公開日 | 2005-02-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design of a calcium-binding protein with desired structure in a cell adhesion molecule.
J.Am.Chem.Soc., 127, 2005
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1T1S
 | | Crystal Structure of the Reductoisomerase Complexed with a Bisphosphonate | | 分子名称: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Yajima, S, Hara, K, Sanders, J.M, Yin, F, Ohsawa, K, Wiesner, J, Jomaa, H, Oldfield, E. | | 登録日 | 2004-04-17 | | 公開日 | 2004-09-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystallographic Structures of Two Bisphosphonate:1-Deoxyxylulose-5-Phosphate Reductoisomerase Complexes
J.Am.Chem.Soc., 126, 2004
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1PPW
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1T5F
 | | arginase I-AOH complex | | 分子名称: | (S)-2-AMINO-7,7-DIHYDROXYHEPTANOIC ACID, Arginase 1, MANGANESE (II) ION | | 著者 | Shin, H, Cama, E, Christianson, D.W. | | 登録日 | 2004-05-04 | | 公開日 | 2005-05-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design of amino acid aldehydes as transition-state analogue inhibitors of arginase
J.Am.Chem.Soc., 126, 2004
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1UP6
 | | Structure of the 6-phospho-beta glucosidase from Thermotoga maritima at 2.55 Angstrom resolution in the tetragonal form with manganese, NAD+ and glucose-6-phosphate | | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, 6-PHOSPHO-BETA-GLUCOSIDASE, MANGANESE (II) ION, ... | | 著者 | Varrot, A, Yip, V.L, Withers, S.G, Davies, G.J. | | 登録日 | 2003-09-29 | | 公開日 | 2004-08-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | An Unusual Mechanism of Glycoside Hydrolysis Involving Redox and Elimination Steps by a Family 4 Beta-Glycosidase from Thermotoga Maritima.
J.Am.Chem.Soc., 126, 2004
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1WUG
 | | complex structure of PCAF bromodomain with small chemical ligand NP1 | | 分子名称: | Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-4-METHYL-2-NITROBENZENAMINE | | 著者 | Zeng, L, Li, J, Muller, M, Yan, S, Mujtaba, S, Pan, C, Wang, Z, Zhou, M.M. | | 登録日 | 2004-12-07 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Selective small molecules blocking HIV-1 Tat and coactivator PCAF association
J.Am.Chem.Soc., 127, 2005
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1WUM
 | | Complex structure of PCAF bromodomain with small chemical ligand NP2 | | 分子名称: | Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-2-NITROBENZENAMINE | | 著者 | Zeng, L, Li, J, Muller, M, Yan, S, Mujtaba, S, Pan, C, Wang, Z, Zhou, M.M. | | 登録日 | 2004-12-08 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Selective small molecules blocking HIV-1 Tat and coactivator PCAF association
J.Am.Chem.Soc., 127, 2005
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1X84
 | | IPP isomerase (wt) reacted with (S)-bromohydrine of IPP | | 分子名称: | (S)-4-BROMO-3-HYDROXY-3-METHYLBUTYL DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, MAGNESIUM ION, ... | | 著者 | Wouters, J, Oldfield, E. | | 登録日 | 2004-08-17 | | 公開日 | 2005-01-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | A Crystallographic Investigation of Phosphoantigen Binding to Isopentenyl Pyrophosphate/Dimethylallyl Pyrophosphate Isomerase
J.Am.Chem.Soc., 127, 2005
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1X9R
 | | Umecyanin from Horse Raddish- Crystal Structure of the oxidised form | | 分子名称: | COPPER (II) ION, Umecyanin | | 著者 | Koch, M, Velarde, M, Harrison, M.D, Echt, S, Fischer, M, Messerschmidt, A, Dennison, C. | | 登録日 | 2004-08-24 | | 公開日 | 2005-03-22 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structures of Oxidized and Reduced Stellacyanin from Horseradish Roots
J.Am.Chem.Soc., 127, 2005
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