1KJR
Crystal Structure of the human galectin-3 CRD in complex with a 3'-derivative of N-Acetyllactosamine
Summary for 1KJR
Entry DOI | 10.2210/pdb1kjr/pdb |
Related | 1A3K 1KJL |
Descriptor | Galectin-3, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2,3,5,6-TETRAFLUORO-4-METHOXY-BENZAMIDE, ... (5 entities in total) |
Functional Keywords | all beta, sugar binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 17013.69 |
Authors | Sorme, P.,Arnoux, P.,Kahl-Knutsson, B.,Leffler, H.,Rini, J.M.,Nilsson, U.J. (deposition date: 2001-12-05, release date: 2005-04-12, Last modification date: 2024-02-14) |
Primary citation | Sorme, P.,Arnoux, P.,Kahl-Knutsson, B.,Leffler, H.,Rini, J.M.,Nilsson, U.J. Structural and thermodynamic studies on cation-Pi interactions in lectin-ligand complexes: high-affinity galectin-3 inhibitors through fine-tuning of an arginine-arene interaction. J.Am.Chem.Soc., 127:1737-1743, 2005 Cited by PubMed: 15701008DOI: 10.1021/ja043475p PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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