7U4L
 
 | | Crystal structure of human GPX4-U46C in complex with MAC-5576 | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase, thiophene-2-carbaldehyde | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4K
 | | Crystal structure of human GPX4-U46C-R152H in complex with ML162 | | 分子名称: | 1,2-ETHANEDIOL, 2-chloro-N-(3-chloro-4-methoxyphenyl)-N-[(1R)-2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl]acetamide, Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Xia, X, Soni, R.K, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4N
 | | Crystal structure of human GPX4-U46C in complex with RSL3 | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase, methyl (1S,3R)-2-(chloroacetyl)-1-[4-(methoxycarbonyl)phenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Xia, X, Soni, R.K, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4M
 | | Crystal structure of human GPX4-U46C in complex with LOC1886 | | 分子名称: | 1,2-ETHANEDIOL, 4-methoxy-1H-indole-2-carbaldehyde, Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-28 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4J
 | | Crystal structure of human GPX4-U46C-R152H in complex with TMT10 | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION, ~{N}-(3-chloranyl-4-methoxy-phenyl)ethanamide | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4I
 | | Crystal structure of human GPX4-U46C-R152H in complex with CDS9 | | 分子名称: | 2-bromo-N-[(thiophen-2-yl)methyl]acetamide, Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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