1PW8
 
 | | Covalent Acyl Enzyme Complex Of The R61 DD-Peptidase with A Highly Specific Cephalosporin | | 分子名称: | (6R,7R)-3-[(ACETYLOXY)METHYL]-7-{[(6S)-6-(GLYCYLAMINO)-7-OXIDO-7-OXOHEPTANOYL]AMINO}-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCTANE-2-CARBOXYLATE, D-alanyl-D-alanine carboxypeptidase, GLYCEROL | | 著者 | Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A. | | 登録日 | 2003-07-01 | | 公開日 | 2004-07-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
|
|
1PW9
 | | High resolution crystal structure of an active recombinant fragment of human lung surfactant protein D | | 分子名称: | CALCIUM ION, Pulmonary surfactant-associated protein D | | 著者 | Shrive, A.K, Tharia, H.A, Strong, P, Kishore, U, Burns, I, Rizkallah, P.J, Reid, K.B, Greenhough, T.J. | | 登録日 | 2003-07-01 | | 公開日 | 2003-08-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High resolution structural insights into ligand binding and immune cell recognition by human lung surfactant protein D
J.Mol.Biol., 331, 2003
|
|
1PWA
 | | Crystal structure of Fibroblast Growth Factor 19 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fibroblast growth factor-19, GLYCEROL, ... | | 著者 | Harmer, N.J, Pellegrini, L, Chirgadze, D, Fernandez-Recio, J, Blundell, T.L. | | 登録日 | 2003-07-01 | | 公開日 | 2004-01-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity.
Biochemistry, 43, 2004
|
|
1PWB
 | | High resolution crystal structure of an active recombinant fragment of human lung surfactant protein D with maltose | | 分子名称: | CALCIUM ION, Pulmonary surfactant-associated protein D, alpha-D-glucopyranose, ... | | 著者 | Shrive, A.K, Tharia, H.A, Strong, P, Kishore, U, Burns, I, Rizkallah, P.J, Reid, K.B, Greenhough, T.J. | | 登録日 | 2003-07-01 | | 公開日 | 2003-08-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | High-resolution structural insights into ligand binding and immune cell recognition by human lung surfactant protein D
J.Mol.Biol., 331, 2003
|
|
1PWC
 | | penicilloyl acyl enzyme complex of the Streptomyces R61 DD-peptidase with penicillin G | | 分子名称: | D-alanyl-D-alanine carboxypeptidase, OPEN FORM - PENICILLIN G | | 著者 | Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A. | | 登録日 | 2003-07-01 | | 公開日 | 2004-07-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
|
|
1PWD
 | | Covalent acyl enzyme complex of the Streptomyces R61 DD-peptidase with cephalosporin C | | 分子名称: | (2R)-5-(acetyloxymethyl)-2-[(1R)-1-[[(5R)-5-azanyl-6-oxidanyl-6-oxidanylidene-hexanoyl]amino]-2-oxidanylidene-ethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase precursor | | 著者 | Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A. | | 登録日 | 2003-07-01 | | 公開日 | 2004-07-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
|
|
1PWE
 | | Rat Liver L-Serine Dehydratase Apo Enzyme | | 分子名称: | L-serine dehydratase | | 著者 | Yamada, T, Komoto, J, Takata, Y, Ogawa, H, Takusagawa, F. | | 登録日 | 2003-07-01 | | 公開日 | 2003-12-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of serine dehydratase from rat liver.
Biochemistry, 42, 2003
|
|
1PWF
 | | One Sugar Pucker Fits All: Pairing Versatility Despite Conformational Uniformity in TNA | | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(2MU)P*(FA2)P*CP*GP*C)-3', SPERMINE | | 著者 | Pallan, P.S, Wilds, C.J, Wawrzak, Z, Krishnamurthy, R, Eschenmoser, A, Egli, M. | | 登録日 | 2003-07-01 | | 公開日 | 2004-07-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | | 主引用文献 | Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis.
ANGEW.CHEM.INT.ED.ENGL., 42, 2003
|
|
1PWG
 | | Covalent Penicilloyl Acyl Enzyme Complex Of The Streptomyces R61 DD-Peptidase With A Highly Specific Penicillin | | 分子名称: | (2R,4S)-2-[(1R)-1-{[(6S)-6-carboxy-6-(glycylamino)hexanoyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase | | 著者 | Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A. | | 登録日 | 2003-07-01 | | 公開日 | 2004-07-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.074 Å) | | 主引用文献 | Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
|
|
1PWH
 | | Rat Liver L-Serine Dehydratase- Complex with PYRIDOXYL-(O-METHYL-SERINE)-5-MONOPHOSPHATE | | 分子名称: | L-serine dehydratase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-O-METHYL-L-SERINE, POTASSIUM ION | | 著者 | Yamada, T, Komoto, J, Takata, Y, Ogawa, H, Takusagawa, F. | | 登録日 | 2003-07-01 | | 公開日 | 2003-12-02 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of serine dehydratase from rat liver.
Biochemistry, 42, 2003
|
|
1PWJ
 | | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly | | 分子名称: | dynein light chain-2 | | 著者 | Wang, W, Lo, K.W.-H, Kan, H.-M, Fan, J.-S, Zhang, M. | | 登録日 | 2003-07-02 | | 公開日 | 2003-10-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of the Domain-swapped Dimer Assembly
J.Biol.Chem., 278, 2003
|
|
1PWK
 | | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly | | 分子名称: | dynein light chain-2 | | 著者 | Wang, W, Lo, K.W.-H, Kan, H.-M, Fan, J.-S, Zhang, M. | | 登録日 | 2003-07-02 | | 公開日 | 2003-10-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of the Domain-swapped Dimer Assembly
J.Biol.Chem., 278, 2003
|
|
1PWL
 | | Crystal structure of human Aldose Reductase complexed with NADP and Minalrestat | | 分子名称: | 2[4-BROMO-2-FLUOROPHENYL)METHYL]-6-FLUOROSPIRO[ISOQUINOLINE-4-(1H),3'-PYRROLIDINE]-1,2',3,5'(2H)-TETRONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, aldose reductase | | 著者 | El-Kabbani, O, Darmanin, C, Schneider, T.R, Hazemann, I, Ruiz, F, Oka, M, Joachimiak, A, Schulze-Briese, C, Tomizaki, T, Mitschler, A, Podjarny, A. | | 登録日 | 2003-07-02 | | 公開日 | 2004-02-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors
PROTEINS, 55, 2004
|
|
1PWM
 | | Crystal structure of human Aldose Reductase complexed with NADP and Fidarestat | | 分子名称: | (2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | El-Kabbani, O, Darmanin, C, Schneider, T.R, Hazemann, I, Ruiz, F, Oka, M, Joachimiak, A, Schulze-Briese, C, Tomizaki, T, Mitschler, A, Podjarny, A. | | 登録日 | 2003-07-02 | | 公開日 | 2004-02-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (0.92 Å) | | 主引用文献 | Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors
PROTEINS, 55, 2004
|
|
1PWO
 | |
1PWP
 | | Crystal Structure of the Anthrax Lethal Factor complexed with Small Molecule Inhibitor NSC 12155 | | 分子名称: | Lethal factor, N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA, ZINC ION | | 著者 | Wong, T.Y, Schwarzenbacher, R, Liddington, R.C. | | 登録日 | 2003-07-02 | | 公開日 | 2004-01-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Identification of small molecule inhibitors of anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
|
|
1PWQ
 | | Crystal structure of Anthrax Lethal Factor complexed with Thioacetyl-Tyr-Pro-Met-Amide, a metal-chelating peptidyl small molecule inhibitor | | 分子名称: | Lethal factor, N-(SULFANYLACETYL)TYROSYLPROLYLMETHIONINAMIDE, ZINC ION | | 著者 | Wong, T.Y, Schwarzenbacher, R, Liddington, R.C. | | 登録日 | 2003-07-02 | | 公開日 | 2004-01-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | | 主引用文献 | The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
|
|
1PWT
 | | THERMODYNAMIC ANALYSIS OF ALPHA-SPECTRIN SH3 AND TWO OF ITS CIRCULAR PERMUTANTS WITH DIFFERENT LOOP LENGTHS: DISCERNING THE REASONS FOR RAPID FOLDING IN PROTEINS | | 分子名称: | ALPHA SPECTRIN | | 著者 | Martinez, J.C, Viguera, A.R, Berisio, R, Wilmanns, M, Mateo, P.L, Filmonov, V.V, Serrano, L. | | 登録日 | 1998-10-06 | | 公開日 | 1999-05-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Thermodynamic analysis of alpha-spectrin SH3 and two of its circular permutants with different loop lengths: discerning the reasons for rapid folding in proteins.
Biochemistry, 38, 1999
|
|
1PWU
 | | Crystal Structure of Anthrax Lethal Factor complexed with (3-(N-hydroxycarboxamido)-2-isobutylpropanoyl-Trp-methylamide), a known small molecule inhibitor of matrix metalloproteases. | | 分子名称: | 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE, Lethal factor, ZINC ION | | 著者 | Wong, T.Y, Schwarzenbacher, R, Liddington, R.C. | | 登録日 | 2003-07-02 | | 公開日 | 2004-02-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
|
|
1PWV
 | |
1PWW
 | |
1PWX
 | | Crystal structure of the haloalcohol dehalogenase HheC complexed with bromide | | 分子名称: | BROMIDE ION, halohydrin dehalogenase | | 著者 | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2003-07-02 | | 公開日 | 2003-10-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
EMBO J., 22, 2003
|
|
1PWY
 | | CRYSTAL STRUCTURE OF HUMAN PNP COMPLEXED WITH ACYCLOVIR | | 分子名称: | 9-HYROXYETHOXYMETHYLGUANINE, Purine nucleoside phosphorylase, SULFATE ION | | 著者 | Dos Santos, D.M, Canduri, F, Pereira, J.H, Vinicius Bertacine Dias, M, Silva, R.G, Mendes, M.A, Palma, M.S, Basso, L.A, De Azevedo, W.F, Santos, D.S. | | 登録日 | 2003-07-02 | | 公開日 | 2004-03-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir.
Biochem.Biophys.Res.Commun., 308, 2003
|
|
1PWZ
 | | Crystal structure of the haloalcohol dehalogenase HheC complexed with (R)-styrene oxide and chloride | | 分子名称: | CHLORIDE ION, R-STYRENE OXIDE, halohydrin dehalogenase | | 著者 | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2003-07-02 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
EMBO J., 22, 2003
|
|
1PX0
 | | Crystal structure of the haloalcohol dehalogenase HheC complexed with the haloalcohol mimic (R)-1-para-nitro-phenyl-2-azido-ethanol | | 分子名称: | (R)-1-PARA-NITRO-PHENYL-2-AZIDO-ETHANOL, halohydrin dehalogenase | | 著者 | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2003-07-02 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
EMBO J., 22, 2003
|
|
