1PMD
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![BU of 1pmd by Molmil](/molmil-images/mine/1pmd) | PENICILLIN-BINDING PROTEIN 2X (PBP-2X) | Descriptor: | PEPTIDOGLYCAN SYNTHESIS MULTIFUNCTIONAL ENZYME | Authors: | Pares, S, Mouz, N, Dideberg, O. | Deposit date: | 1996-02-05 | Release date: | 1997-02-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme. Nat.Struct.Biol., 3, 1996
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1BZA
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![BU of 1bza by Molmil](/molmil-images/mine/1bza) | BETA-LACTAMASE TOHO-1 FROM ESCHERICHIA COLI TUH12191 | Descriptor: | BETA-LACTAMASE, SULFATE ION | Authors: | Ibuka, A, Taguchi, A, Ishiguro, M, Fushinobu, S, Ishii, Y, Kamitori, S, Okuyama, K, Yamaguchi, K, Konno, M, Matsuzawa, H. | Deposit date: | 1998-10-28 | Release date: | 1999-04-27 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the E166A mutant of extended-spectrum beta-lactamase Toho-1 at 1.8 A resolution. J.Mol.Biol., 285, 1999
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1QME
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![BU of 1qme by Molmil](/molmil-images/mine/1qme) | PENICILLIN-BINDING PROTEIN 2X (PBP-2X) | Descriptor: | PENICILLIN-BINDING PROTEIN 2X, SULFATE ION | Authors: | Gordon, E.J, Mouz, N, Duee, E, Dideberg, O. | Deposit date: | 1999-09-28 | Release date: | 2000-05-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Crystal Structure of the Penicillin-Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance. J.Mol.Biol., 299, 2000
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1QMF
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![BU of 1qmf by Molmil](/molmil-images/mine/1qmf) | PENICILLIN-BINDING PROTEIN 2X (PBP-2X) ACYL-ENZYME COMPLEX | Descriptor: | 2-[CARBOXY-(2-FURAN-2-YL-2-METHOXYIMINO-ACETYLAMINO)-METHYL]-5-METHYL-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, CEFUROXIME (OCT-3-ENE FORM), PENICILLIN-BINDING PROTEIN 2X | Authors: | Gordon, E.J, Mouz, N, Duee, E, Dideberg, O. | Deposit date: | 1999-09-28 | Release date: | 2000-05-25 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Crystal Structure of the Penicillin Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance J.Mol.Biol., 299, 2000
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1FOF
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![BU of 1fof by Molmil](/molmil-images/mine/1fof) | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 | Descriptor: | BETA LACTAMASE OXA-10, COBALT (II) ION, SULFATE ION | Authors: | Paetzel, M, Danel, F, de Castro, L, Mosimann, S.C, Page, M.G.P, Strynadka, N.C.J. | Deposit date: | 2000-08-28 | Release date: | 2000-10-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the class D beta-lactamase OXA-10. Nat.Struct.Biol., 7, 2000
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1EWZ
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![BU of 1ewz by Molmil](/molmil-images/mine/1ewz) | CRYSTAL STRUCTURE OF THE OXA-10 BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA | Descriptor: | BETA LACTAMASE OXA-10 | Authors: | Golemi, D, Maveyraud, L, Vakulenko, S, Tranier, S, Ishiwata, A, Kotra, L.P, Samama, J.P, Mobashery, S. | Deposit date: | 2000-04-28 | Release date: | 2000-11-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The First Structural and Mechanistic Insights for Class D beta-Lactamases: Evidence for a Novel Catalytic Process for Turnover of beta-Lactam Antibiotics J.Am.Chem.Soc., 122, 2000
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1E3U
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![BU of 1e3u by Molmil](/molmil-images/mine/1e3u) | MAD structure of OXA10 class D beta-lactamase | Descriptor: | 1,2-ETHANEDIOL, BETA-LACTAMASE OXA-10, GOLD (I) CYANIDE ION, ... | Authors: | Maveyraud, L, Golemi, D, Kotra, L.P, Tranier, S, Vakulenko, S, Mobashery, S, Samama, J.P. | Deposit date: | 2000-06-23 | Release date: | 2001-01-12 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Insights Into Class D Beta-Lactamases are Revealed by the Crystal Structure of the Oxa10 Enzyme from Pseudomonas Aeruginosa Structure, 8, 2000
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1E4D
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![BU of 1e4d by Molmil](/molmil-images/mine/1e4d) | Structure of OXA10 beta-lactamase at pH 8.3 | Descriptor: | 1,2-ETHANEDIOL, BETA-LACTAMASE OXA-10, SULFATE ION | Authors: | Maveyraud, L, Golemi, D, Kotra, L.P, Tranier, S, Vakulenko, S, Mobashery, S, Samama, J.P. | Deposit date: | 2000-07-03 | Release date: | 2001-01-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Insights Into Class D Beta-Lactamases are Revealed by the Crystal Structure of the Oxa10 Enzyme from Pseudomonas Aeruginosa Structure, 8, 2000
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1H8Z
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![BU of 1h8z by Molmil](/molmil-images/mine/1h8z) | Crystal structure of the class D beta-lactamase OXA-13 | Descriptor: | BETA-LACTAMASE, SULFATE ION | Authors: | Pernot, L, Frenois, F, Rybkine, T, L'Hermite, G, Petrella, S, Delettre, J, Jarlier, V, Collatz, E, Sougakoff, W. | Deposit date: | 2001-02-17 | Release date: | 2001-07-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of the Class D B-Lactamase Oxa-13 in the Native Form and in Complex with Meropenem J.Mol.Biol., 310, 2001
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1H8Y
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![BU of 1h8y by Molmil](/molmil-images/mine/1h8y) | Crystal structure of the class D beta-lactamase OXA-13 in complex with meropenem | Descriptor: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, BETA-LACTAMASE, SULFATE ION | Authors: | Pernot, L, Frenois, F, Rybkine, T, L'Hermite, G, Petrella, S, Delettre, J, Jarlier, V, Collatz, E, Sougakoff, W. | Deposit date: | 2001-02-17 | Release date: | 2001-07-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of the Class D B-Lactamase Oxa-13 in the Native Form and in Complex with Meropenem J.Mol.Biol., 310, 2001
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1K4F
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![BU of 1k4f by Molmil](/molmil-images/mine/1k4f) | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.6 A RESOLUTION | Descriptor: | Beta-lactamase PSE-2, SULFATE ION | Authors: | Kerff, F, Fonze, E, Bouillene, F, Frere, J.M, Charlier, P. | Deposit date: | 2001-10-08 | Release date: | 2001-10-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the class D beta-lactamase OXA-2 To be Published
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1K4E
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![BU of 1k4e by Molmil](/molmil-images/mine/1k4e) | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASES OXA-10 DETERMINED BY MAD PHASING WITH SELENOMETHIONINE | Descriptor: | Beta-lactamase PSE-2, SULFATE ION | Authors: | Kerff, F, Fonze, E, Bouillene, F, Frere, J.M, Charlier, P. | Deposit date: | 2001-10-08 | Release date: | 2001-10-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | STRUCTURE OF CLASS D BETA-LACTAMASE OXA-2 To be Published
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1K25
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![BU of 1k25 by Molmil](/molmil-images/mine/1k25) | |
1K54
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![BU of 1k54 by Molmil](/molmil-images/mine/1k54) | OXA-10 class D beta-lactamase partially acylated with reacted 6beta-(1-hydroxy-1-methylethyl) penicillanic acid | Descriptor: | (1R)-2-(1-CARBOXY-2-HYDROXY-2-METHYL-PROPYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, 1,2-ETHANEDIOL, Beta lactamase OXA-10, ... | Authors: | Golemi, D, Maveyraud, L, Vakulenko, S, Samama, J.P, Mobashery, S. | Deposit date: | 2001-10-10 | Release date: | 2001-11-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Critical involvement of a carbamylated lysine in catalytic function of class D beta-lactamases. Proc.Natl.Acad.Sci.USA, 98, 2001
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1K55
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![BU of 1k55 by Molmil](/molmil-images/mine/1k55) | OXA 10 class D beta-lactamase at pH 7.5 | Descriptor: | 1,2-ETHANEDIOL, Beta lactamase OXA-10, SULFATE ION | Authors: | Golemi, D, Maveyraud, L, Vakulenko, S, Samama, J.P, Mobashery, S. | Deposit date: | 2001-10-10 | Release date: | 2001-11-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Critical involvement of a carbamylated lysine in catalytic function of class D beta-lactamases. Proc.Natl.Acad.Sci.USA, 98, 2001
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1K57
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![BU of 1k57 by Molmil](/molmil-images/mine/1k57) | OXA 10 class D beta-lactamase at pH 6.0 | Descriptor: | BETA LACTAMASE OXA-10, SULFATE ION | Authors: | Golemi, D, Maveyraud, L, Vakulenko, S, Samama, J.P, Mobashery, S. | Deposit date: | 2001-10-10 | Release date: | 2001-11-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Critical involvement of a carbamylated lysine in catalytic function of class D beta-lactamases. Proc.Natl.Acad.Sci.USA, 98, 2001
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1K56
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![BU of 1k56 by Molmil](/molmil-images/mine/1k56) | OXA 10 class D beta-lactamase at pH 6.5 | Descriptor: | OXA10 beta-lactamase, SULFATE ION | Authors: | Golemi, D, Maveyraud, L, Vakulenko, S, Samama, J.P, Mobashery, S. | Deposit date: | 2001-10-10 | Release date: | 2001-11-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Critical involvement of a carbamylated lysine in catalytic function of class D beta-lactamases. Proc.Natl.Acad.Sci.USA, 98, 2001
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1H5X
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![BU of 1h5x by Molmil](/molmil-images/mine/1h5x) | |
1MWT
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![BU of 1mwt by Molmil](/molmil-images/mine/1mwt) | |
1MWR
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![BU of 1mwr by Molmil](/molmil-images/mine/1mwr) | |
1MWS
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![BU of 1mws by Molmil](/molmil-images/mine/1mws) | |
1MWU
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![BU of 1mwu by Molmil](/molmil-images/mine/1mwu) | Structure of methicillin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.60 A resolution. | Descriptor: | (2R,4S)-2-[(1R)-1-{[(2,6-dimethoxyphenyl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CADMIUM ION, CHLORIDE ION, ... | Authors: | Lim, D.C, Strynadka, N.C.J. | Deposit date: | 2002-10-01 | Release date: | 2002-11-06 | Last modified: | 2012-02-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus. Nat.Struct.Biol., 9, 2002
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1IYO
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![BU of 1iyo by Molmil](/molmil-images/mine/1iyo) | Toho-1 beta-Lactamase In Complex With Cefotaxime | Descriptor: | CEFOTAXIME, C3' cleaved, open, ... | Authors: | Shimamura, T, Ibuka, A, Fushinobu, S, Wakagi, T, Ishiguro, M, Ishii, Y, Matsuzawa, H. | Deposit date: | 2002-09-04 | Release date: | 2002-12-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin. J.Biol.Chem., 277, 2002
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1IYQ
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![BU of 1iyq by Molmil](/molmil-images/mine/1iyq) | Toho-1 beta-Lactamase In Complex With Benzylpenicillin | Descriptor: | OPEN FORM - PENICILLIN G, SULFATE ION, Toho-1 beta-lactamase | Authors: | Shimamura, T, Ibuka, A, Fushinobu, S, Wakagi, T, Ishiguro, M, Ishii, Y, Matsuzawa, H. | Deposit date: | 2002-09-04 | Release date: | 2002-12-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin. J.Biol.Chem., 277, 2002
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1IYP
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![BU of 1iyp by Molmil](/molmil-images/mine/1iyp) | Toho-1 beta-Lactamase In Complex With Cephalothin | Descriptor: | CEPHALOTHIN GROUP, SULFATE ION, Toho-1 beta-lactamase | Authors: | Shimamura, T, Ibuka, A, Fushinobu, S, Wakagi, T, Ishiguro, M, Ishii, Y, Matsuzawa, H. | Deposit date: | 2002-09-04 | Release date: | 2002-12-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin. J.Biol.Chem., 277, 2002
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