1K54

OXA-10 class D beta-lactamase partially acylated with reacted 6beta-(1-hydroxy-1-methylethyl) penicillanic acid

Summary for 1K54

Entry DOI	10.2210/pdb1k54/pdb
Related	1K55 1K56 1K57 1e3u 1e4d
Descriptor	Beta lactamase OXA-10, SULFATE ION, (1R)-2-(1-CARBOXY-2-HYDROXY-2-METHYL-PROPYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, ... (6 entities in total)
Functional Keywords	beta-lactamase, antibiotic resistance, carbamylation, hydrolase
Biological source	Pseudomonas aeruginosa More
Total number of polymer chains	4
Total formula weight	112743.32
Authors	Golemi, D.,Maveyraud, L.,Vakulenko, S.,Samama, J.P.,Mobashery, S. (deposition date: 2001-10-10, release date: 2001-11-07, Last modification date: 2023-11-15)
Primary citation	Golemi, D.,Maveyraud, L.,Vakulenko, S.,Samama, J.P.,Mobashery, S. Critical involvement of a carbamylated lysine in catalytic function of class D beta-lactamases. Proc.Natl.Acad.Sci.USA, 98:14280-14285, 2001 Cited by PubMed: 11724923 DOI: 10.1073/pnas.241442898 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation