8I7P
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![BU of 8i7p by Molmil](/molmil-images/mine/8i7p) | Crystal structure of Ricin A chain bound with N2-(2-amino-4-oxo-3,4-dihydropteridine-7-carbonyl)glycyl-L-tyrosine | Descriptor: | 6-(2-ethyl-4-hydroxyphenyl)-1H-indazole-3-carboxamide, Ricin A chain, SULFATE ION | Authors: | Goto, M, Sakamoto, N, Higashi, S, Kawata, R, Nagatsu, K, Saito, R. | Deposit date: | 2023-02-01 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor. J Enzyme Inhib Med Chem, 38, 2023
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5Z37
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![BU of 5z37 by Molmil](/molmil-images/mine/5z37) | |
6CWG
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![BU of 6cwg by Molmil](/molmil-images/mine/6cwg) | Ricin catalytic subunit bound go A9 VHH antibody | Descriptor: | CHLORIDE ION, Ricin, VHH antibody | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2018-03-30 | Release date: | 2019-01-16 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity. Protein Eng. Des. Sel., 31, 2018
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4M5A
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![BU of 4m5a by Molmil](/molmil-images/mine/4m5a) | Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina inhibited by asymmetric dimethyl arginine at 1.70 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NG,NG-DIMETHYL-L-ARGININE, rRNA N-glycosidase | Authors: | Yamini, S, Pandey, S, Kushwaha, G.S, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2013-08-08 | Release date: | 2013-08-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the complex of Ribosome inactivating protein from Momordica balsamina inhibited by asymmetric dimethyl arginine at 1.70 A resolution To be Published
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8CX8
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![BU of 8cx8 by Molmil](/molmil-images/mine/8cx8) | Stx2A1-BTB13086 | Descriptor: | 1,2-ETHANEDIOL, 5-(4-chlorophenyl)furan-2-carboxylic acid, CHLORIDE ION, ... | Authors: | Rudolph, M.J, Li, X.P. | Deposit date: | 2022-05-20 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.905 Å) | Cite: | Stx2A1-BTB13086 To Be Published
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6YTS
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![BU of 6yts by Molmil](/molmil-images/mine/6yts) | Solution NMR structure of type-I ribosome-inactivating protein trichobakin (TBK) | Descriptor: | Trichobakin | Authors: | Britikov, V.V, Bocharov, E.V, Britikova, E.V, Le, T.B.T, Phan, C.V, Boyko, K.M, Arseniev, A.S, Usanov, S.A. | Deposit date: | 2020-04-24 | Release date: | 2020-05-06 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structure and dynamics of type-I ribosome-inactivating protein trichobakin (TBK) To Be Published
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8GCW
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![BU of 8gcw by Molmil](/molmil-images/mine/8gcw) | Stx2A1(Y77A)-P6 peptide | Descriptor: | P stalk protein, rRNA N-glycosylase | Authors: | Rudolph, M.J, Li, X.P. | Deposit date: | 2023-03-03 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the Stx2A1(Y77A) in complex with P6 peptide. To Be Published
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2B7U
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![BU of 2b7u by Molmil](/molmil-images/mine/2b7u) | |
1UQ5
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![BU of 1uq5 by Molmil](/molmil-images/mine/1uq5) | RICIN A-CHAIN (RECOMBINANT) N122A MUTANT | Descriptor: | ACETATE ION, RICIN, SULFATE ION | Authors: | Marsden, C.J, Fulop, V. | Deposit date: | 2003-10-15 | Release date: | 2004-01-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The Effect of Mutations Surrounding and within the Active Site on the Catalytic Activity of Ricin a Chain Eur.J.Biochem., 271, 2004
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1UQ4
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![BU of 1uq4 by Molmil](/molmil-images/mine/1uq4) | RICIN A-CHAIN (RECOMBINANT) R213D MUTANT | Descriptor: | RICIN, SULFATE ION | Authors: | Marsden, C.J, Fulop, V. | Deposit date: | 2003-10-15 | Release date: | 2004-01-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Effect of Mutations Surrounding and within the Active Site on the Catalytic Activity of Ricin a Chain Eur.J.Biochem., 271, 2004
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6Z1Y
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![BU of 6z1y by Molmil](/molmil-images/mine/6z1y) | Crystal structure of type-I ribosome-inactivating protein trichobakin (TBK) | Descriptor: | SODIUM ION, Trichobakin | Authors: | Boyko, K.M, Nikolaeva, A.Y, Britikov, V.V, Bocharov, E.V, Britikova, E.V, Le, T.B.T, Phan, C.V, Popov, V.O, Usanov, S.A. | Deposit date: | 2020-05-14 | Release date: | 2020-05-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of type-I ribosome-inactivating protein trichobakin (TBK) To Be Published
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4Q2V
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![BU of 4q2v by Molmil](/molmil-images/mine/4q2v) | Crystal Structure of Ricin A chain complexed with Baicalin inhibitor | Descriptor: | 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, Ricin | Authors: | Deng, X, Li, X, Dong, J, Chen, Y. | Deposit date: | 2014-04-10 | Release date: | 2015-04-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.198 Å) | Cite: | Baicalin inhibits the lethality of ricin in mice by inducing protein oligomerization. J.Biol.Chem., 290, 2015
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5ILW
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![BU of 5ilw by Molmil](/molmil-images/mine/5ilw) | Crystal structure of the complex of type 1 Ribosome inactivating protein from Momordica balsamina with Uridine at 1.97 Angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ribosome inactivating protein, ... | Authors: | Singh, P.K, Pandey, S, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2016-03-05 | Release date: | 2016-03-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Binding and structural studies of the complexes of type 1 ribosome inactivating protein from Momordica balsamina with uracil and uridine. Proteins, 87, 2019
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4Q9F
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![BU of 4q9f by Molmil](/molmil-images/mine/4q9f) | Crystal structure of type 1 ribosome inactivating protein from Momordica balsamina in complex with guanosine mono phosphate at 1.75 Angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, ... | Authors: | Kushwaha, G.S, Pandey, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2014-05-01 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of type 1 ribosome inactivating protein from Momordica balsamina in complex with guanosine mono phosphate at 1.75 Angstrom resolution To be Published
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5U4M
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![BU of 5u4m by Molmil](/molmil-images/mine/5u4m) | RTA-V1C7-G29R-no_salt | Descriptor: | CHLORIDE ION, Ricin, V1C7 VHH antibody | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2016-12-05 | Release date: | 2017-12-13 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies. Proteins, 85, 2017
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5U4L
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![BU of 5u4l by Molmil](/molmil-images/mine/5u4l) | RTA-V1C7_G29R-high-salt | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2016-12-05 | Release date: | 2017-12-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies. Proteins, 85, 2017
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5J57
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![BU of 5j57 by Molmil](/molmil-images/mine/5j57) | V5E1-RTA complex | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Ricin, ... | Authors: | Rudolph, M.J. | Deposit date: | 2016-04-01 | Release date: | 2016-12-07 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit. J. Biol. Chem., 292, 2017
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4RZJ
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![BU of 4rzj by Molmil](/molmil-images/mine/4rzj) | Structure of the complex of type 1 ribosome inactivating protein from Momordica balsamina with N-acetylglucosamine at 1.98 Angstrom resolution using crystals grown in different conditions | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ribosome inactivating protein | Authors: | Pandey, S, Kushwaha, G.S, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2014-12-22 | Release date: | 2015-01-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure of the complex of type 1 ribosome inactivating protein from Momordica balsamina with N-acetylglucosamine at 1.98 Angstrom resolution using crystals grown in different conditions TO BE PUBLISHED
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5SV3
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![BU of 5sv3 by Molmil](/molmil-images/mine/5sv3) | RTA1-33/44-198 (RVEC) bound to Single Domain Antibody A3C8 | Descriptor: | Anti-Ricin A-chain Single Domain Antibody (sdAb) A3C8, Ricin, SULFATE ION | Authors: | Compton, J.R, Legler, P.M. | Deposit date: | 2016-08-04 | Release date: | 2016-10-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Stability of isolated antibody-antigen complexes as a predictive tool for selecting toxin neutralizing antibodies. MAbs, 9, 2017
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5J56
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![BU of 5j56 by Molmil](/molmil-images/mine/5j56) | RTA-V1C7 | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | Authors: | Rudolph, M.J. | Deposit date: | 2016-04-01 | Release date: | 2016-12-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit. J. Biol. Chem., 292, 2017
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2VS6
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![BU of 2vs6 by Molmil](/molmil-images/mine/2vs6) | K173A, R174A, K177A-trichosanthin | Descriptor: | RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN | Authors: | Too, P.H, Ma, M.K, Mak, A.N, Tung, C.K, Zhu, G, Au, S.W, Wong, K.B, Shaw, P.C, Ng, A. | Deposit date: | 2008-04-21 | Release date: | 2008-12-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The C-Terminal Fragment of the Ribosomal P Protein Complexed to Trichosanthin Reveals the Interaction between the Ribosome-Inactivating Protein and the Ribosome. Nucleic Acids Res., 37, 2009
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5GU4
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![BU of 5gu4 by Molmil](/molmil-images/mine/5gu4) | rRNA N-glycosylase RTA | Descriptor: | GLY-PHE-GLY-LEU-PHE-ASP, GLYCEROL, Ricin | Authors: | Shi, W.W, Tang, Y.S, Sze, S.Y, Zhu, Z.N, Wong, K.B, Shaw, P.C. | Deposit date: | 2016-08-24 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2 Toxins, 8, 2016
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3BWH
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![BU of 3bwh by Molmil](/molmil-images/mine/3bwh) | Atomic resolution structure of cucurmosin, a novel type 1 RIP from the sarcocarp of Cucurbita moschata | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, beta-D-xylopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L. | Deposit date: | 2008-01-09 | Release date: | 2008-10-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Atomic resolution structure of cucurmosin, a novel type 1 ribosome-inactivating protein from the sarcocarp of Cucurbita moschata. J.Struct.Biol., 164, 2008
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2JDL
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![BU of 2jdl by Molmil](/molmil-images/mine/2jdl) | Structure of C-terminal region of acidic P2 ribosomal protein complexed with trichosanthin | Descriptor: | ACIDIC RIBOSOMAL PROTEIN P2, RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN | Authors: | Too, P.H, Mak, A.N, Zhu, G, Au, S.W, Wong, K.B, Shaw, P.C. | Deposit date: | 2007-01-11 | Release date: | 2008-02-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The C-Terminal Fragment of the Ribosomal P Protein Complexed to Trichosanthin Reveals the Interaction between the Ribosome-Inactivating Protein and the Ribosome. Nucleic Acids Res., 37, 2009
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6URY
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![BU of 6ury by Molmil](/molmil-images/mine/6ury) | Crystal structure of ricin A chain in complex with inhibitor 9-oxo-4-fluorenecarboxamide | Descriptor: | 1,2-ETHANEDIOL, 9-oxo-9H-fluorene-4-carboxamide, CHLORIDE ION, ... | Authors: | Harijan, R.K, Li, X.P, Bonanno, J.B, Almo, S.C, Tumer, N.E, Schramm, V.L. | Deposit date: | 2019-10-24 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Small Molecule Inhibitors Targeting the Interaction of Ricin Toxin A Subunit with Ribosomes. Acs Infect Dis., 6, 2020
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