3HBT
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![BU of 3hbt by Molmil](/molmil-images/mine/3hbt) | The structure of native G-actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, CALCIUM ION, ... | Authors: | Wang, H, Robinson, R.C, Burtnick, L.D. | Deposit date: | 2009-05-05 | Release date: | 2010-05-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structure of native G-actin Cytoskeleton (Hoboken), 67, 2010
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4FO0
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![BU of 4fo0 by Molmil](/molmil-images/mine/4fo0) | Human actin-related protein Arp8 in its ATP-bound state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 8, CHLORIDE ION, ... | Authors: | Gerhold, C.B, Lakomek, K, Seifert, F.U, Hopfner, K.-P. | Deposit date: | 2012-06-20 | Release date: | 2012-09-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Actin-related protein 8 and its contribution to nucleosome binding. Nucleic Acids Res., 40, 2012
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6QRI
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![BU of 6qri by Molmil](/molmil-images/mine/6qri) | Structure of rabbit G-actin in complex with chivosazole A | Descriptor: | (2~{R},3~{R},5~{S},6~{E},8~{E},10~{Z},12~{S},13~{R},16~{Z},18~{E},20~{Z},22~{E},24~{R},25~{S},26~{E},28~{Z})-13-[(2~{S},3~{S},5~{S})-3,5-bis(oxidanyl)hexan-2-yl]-25-[(2~{R},3~{R},4~{S},5~{R},6~{R})-3,4-dimethoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-3-methoxy-2,12,22,24-tetramethyl-5-oxidanyl-14,32-dioxa-33-azabicyclo[28.2.1]tritriaconta-1(33),6,8,10,16,18,20,22,26,28,30-undecaen-15-one, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Schneider, S, Wang, S, Zahler, S. | Deposit date: | 2019-02-19 | Release date: | 2019-07-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Chivosazole A Modulates Protein-Protein Interactions of Actin. J.Nat.Prod., 82, 2019
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2FXU
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![BU of 2fxu by Molmil](/molmil-images/mine/2fxu) | X-ray Structure of Bistramide A- Actin Complex at 1.35 A resolution. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Rizvi, S.A, Tereshko, V, Kossiakoff, A.A, Kozmin, S.A. | Deposit date: | 2006-02-06 | Release date: | 2006-03-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure of bistramide a-actin complex at a 1.35 A resolution J.Am.Chem.Soc., 128, 2006
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3UE5
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![BU of 3ue5 by Molmil](/molmil-images/mine/3ue5) | ECP-cleaved Actin in complex with Spir domain D | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Chen, C, Phillips, M, Sawaya, M.R, Ralston, C.Y, Quinlan, M.E. | Deposit date: | 2011-10-28 | Release date: | 2012-02-15 | Last modified: | 2012-04-11 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Multiple Forms of Spire-Actin Complexes and their Functional Consequences. J.Biol.Chem., 287, 2012
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4WYB
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![BU of 4wyb by Molmil](/molmil-images/mine/4wyb) | Structure of the Bud6 flank domain in complex with actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Eck, M.J, Park, E, Zheng, W. | Deposit date: | 2014-11-17 | Release date: | 2015-08-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.493 Å) | Cite: | Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif. Structure, 23, 2015
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6DJO
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![BU of 6djo by Molmil](/molmil-images/mine/6djo) | Cryo-EM structure of ADP-actin filaments | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Chou, S.Z, Pollard, T.D. | Deposit date: | 2018-05-25 | Release date: | 2019-02-27 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides. Proc.Natl.Acad.Sci.USA, 116, 2019
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6DJM
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![BU of 6djm by Molmil](/molmil-images/mine/6djm) | Cryo-EM structure of AMPPNP-actin filaments | Descriptor: | Actin, alpha skeletal muscle, MAGNESIUM ION, ... | Authors: | Chou, S.Z, Pollard, T.D. | Deposit date: | 2018-05-25 | Release date: | 2019-02-27 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides. Proc.Natl.Acad.Sci.USA, 116, 2019
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4K41
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![BU of 4k41 by Molmil](/molmil-images/mine/4k41) | Crystal structure of actin in complex with marine macrolide kabiramide C | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Pereira, J.H, Petchprayoon, C, Moriarty, N.W, Fink, S.J, Cecere, G, Paterson, I, Adams, P.D, Marriott, G. | Deposit date: | 2013-04-11 | Release date: | 2014-10-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural and biochemical studies of actin in complex with synthetic macrolide tail analogues. Chemmedchem, 9, 2014
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7R8V
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![BU of 7r8v by Molmil](/molmil-images/mine/7r8v) | Cryo-EM structure of the ADP state actin filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Gong, R, Espinosa de los Reyes, S, Reynolds, M.J, Gurel, P, Alushin, G.M. | Deposit date: | 2021-06-27 | Release date: | 2021-07-28 | Last modified: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia. Sci Adv, 8, 2022
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6DJN
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![BU of 6djn by Molmil](/molmil-images/mine/6djn) | Cryo-EM structure of ADP-Pi-actin filaments | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Chou, S.Z, Pollard, T.D. | Deposit date: | 2018-05-25 | Release date: | 2019-02-27 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides. Proc.Natl.Acad.Sci.USA, 116, 2019
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4M63
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![BU of 4m63 by Molmil](/molmil-images/mine/4m63) | Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | Authors: | Tomchick, D.R, Zahm, J.A, Rosen, M.K. | Deposit date: | 2013-08-08 | Release date: | 2013-10-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.748 Å) | Cite: | The Bacterial Effector VopL Organizes Actin into Filament-like Structures. Cell(Cambridge,Mass.), 155, 2013
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5JLF
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![BU of 5jlf by Molmil](/molmil-images/mine/5jlf) | |
4K42
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![BU of 4k42 by Molmil](/molmil-images/mine/4k42) | Crystal structure of actin in complex with synthetic AplC tail analogue SF01 [(3R,4S,5R,6S,10R,11R,12R)-11-(acetyloxy)-1-(benzyloxy)-14-[formyl(methyl)amino]-5-hydroxy-4,6,10,12-tetramethyl-9-oxotetradecan-3-yl propanoate] | Descriptor: | (3R,4S,5R,6S,10R,11R,12R)-11-(acetyloxy)-1-(benzyloxy)-14-[formyl(methyl)amino]-5-hydroxy-4,6,10,12-tetramethyl-9-oxotetradecan-3-yl propanoate, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Pereira, J.H, Petchprayoon, C, Moriarty, N.W, Fink, S.J, Cecere, G, Paterson, I, Adams, P.D, Marriott, G. | Deposit date: | 2013-04-11 | Release date: | 2014-10-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and biochemical studies of actin in complex with synthetic macrolide tail analogues. Chemmedchem, 9, 2014
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4K43
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![BU of 4k43 by Molmil](/molmil-images/mine/4k43) | Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide] | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Pereira, J.H, Petchprayoon, C, Moriarty, N.W, Fink, S.J, Cecere, G, Paterson, I, Adams, P.D, Marriott, G. | Deposit date: | 2013-04-11 | Release date: | 2014-10-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and biochemical studies of actin in complex with synthetic macrolide tail analogues. Chemmedchem, 9, 2014
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8RU0
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![BU of 8ru0 by Molmil](/molmil-images/mine/8ru0) | Structure of the undecorated barbed end of F-actin. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | Deposit date: | 2024-01-29 | Release date: | 2024-04-10 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
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6KLN
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![BU of 6kln by Molmil](/molmil-images/mine/6kln) | F-actin of cardiac thin filament in high-calcium state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oda, T, Yanagisawa, H, Wakabayashi, T. | Deposit date: | 2019-07-30 | Release date: | 2020-01-15 | Last modified: | 2020-03-11 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin. J.Struct.Biol., 209, 2020
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6KLL
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![BU of 6kll by Molmil](/molmil-images/mine/6kll) | F-actin of cardiac thin filament in low-calcium state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oda, T, Yanagisawa, H, Wakabayashi, T. | Deposit date: | 2019-07-30 | Release date: | 2020-01-15 | Last modified: | 2020-03-11 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin. J.Struct.Biol., 209, 2020
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2HF3
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![BU of 2hf3 by Molmil](/molmil-images/mine/2hf3) | Crystal structure of monomeric Actin in the ADP bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-5C, CALCIUM ION | Authors: | Rould, M.A, Wan, Q, Joel, P.B, Lowey, S, Trybus, K.M. | Deposit date: | 2006-06-22 | Release date: | 2006-08-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of Expressed Non-polymerizable Monomeric Actin in the ADP and ATP States. J.Biol.Chem., 281, 2006
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2HMP
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![BU of 2hmp by Molmil](/molmil-images/mine/2hmp) | Uncomplexed actin cleaved with protease ECP32 | Descriptor: | 1,2-ETHANEDIOL, 2,2',2''-NITRILOTRIETHANOL, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Klenchin, V.A, Khaitlina, S.Y, Rayment, I. | Deposit date: | 2006-07-11 | Release date: | 2006-09-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Crystal structure of polymerization-competent actin J.Mol.Biol., 362, 2006
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6WVT
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![BU of 6wvt by Molmil](/molmil-images/mine/6wvt) | Structural basis of alphaE-catenin - F-actin catch bond behavior | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Xu, X.P, Pokutta, S, Torres, M, Swift, M.F, Hanein, D, Volkmann, N, Weis, W.I. | Deposit date: | 2020-05-06 | Release date: | 2020-10-07 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Structural basis of alpha E-catenin-F-actin catch bond behavior. Elife, 9, 2020
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2ASO
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![BU of 2aso by Molmil](/molmil-images/mine/2aso) | Structure of Rabbit Actin In Complex With Sphinxolide B | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Allingham, J.S, Zampella, A, D'Auria, M.V, Rayment, I. | Deposit date: | 2005-08-23 | Release date: | 2005-10-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity Proc.Natl.Acad.Sci.Usa, 102, 2005
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2GWK
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![BU of 2gwk by Molmil](/molmil-images/mine/2gwk) | |
2HF4
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![BU of 2hf4 by Molmil](/molmil-images/mine/2hf4) | Crystal structure of Monomeric Actin in its ATP-bound state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION | Authors: | Rould, M.A, Wan, Q, Joel, P.B, Lowey, S, Trybus, K.M. | Deposit date: | 2006-06-22 | Release date: | 2006-08-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of Expressed Non-polymerizable Monomeric Actin in the ADP and ATP States. J.Biol.Chem., 281, 2006
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2GWJ
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![BU of 2gwj by Molmil](/molmil-images/mine/2gwj) | |