7NZC
 
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3EG0
 | | Crystal structure of the N114T mutant of ABL-SH3 domain | | Descriptor: | GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1 | | Authors: | Camara-Artigas, A. | | Deposit date: | 2008-09-10 | | Release date: | 2009-09-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
J.Biol.Chem., 285, 2010
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2W10
 | | Mona SH3C in complex | | Descriptor: | GRB2-RELATED ADAPTOR PROTEIN 2, PHOSPHATE ION, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23 | | Authors: | Harkiolaki, M, Feller, S.M. | | Deposit date: | 2008-10-13 | | Release date: | 2009-05-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
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7JT9
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6NMW
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6EDF
 | | Fragment of a tyrosine-protein kinase | | Descriptor: | FYN, GLYCEROL, UNKNOWN ATOM OR ION | | Authors: | Tempel, W, Huang, H, Sochirca, I, Liu, K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Sidhu, S.S, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2018-08-09 | | Release date: | 2018-08-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Fragment of a tyrosine-protein kinase
To be Published
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5EC7
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5VEI
 | | Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2 | | Descriptor: | Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION | | Authors: | Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2017-04-04 | | Release date: | 2017-08-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.33 Å) | | Cite: | Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
To be Published
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5UL6
 | | The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions | | Descriptor: | Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus | | Authors: | Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H. | | Deposit date: | 2017-01-24 | | Release date: | 2017-08-09 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus.
ACS Chem. Biol., 12, 2017
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5ECA
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1Y0M
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2J06
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2J05
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3NGP
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2IIM
 | | SH3 Domain of Human Lck | | Descriptor: | CALCIUM ION, Proto-oncogene tyrosine-protein kinase LCK, TETRAETHYLENE GLYCOL, ... | | Authors: | Romir, J, Egerer-Sieber, C, Muller, Y.A. | | Deposit date: | 2006-09-28 | | Release date: | 2006-11-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs.
J.Mol.Biol., 365, 2007
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1YN8
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6RO9
 | | Human spectrin SH3 domain D48G, E7V, K60V | | Descriptor: | Spectrin alpha, non-erythrocytic 1 | | Authors: | Reverter, D, Navarro, S, Ventura, S. | | Deposit date: | 2019-05-10 | | Release date: | 2020-06-03 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.814 Å) | | Cite: | Human spectrin SH3 domain D48G, E7V, K60V
To Be Published
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6IPY
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5XGG
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4Y92
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6SCW
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5XG9
 | | Crystal Structure of PEG-bound SH3 domain of Myosin IB from Entamoeba histolytica | | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, PENTAETHYLENE GLYCOL, ... | | Authors: | Gautam, G, Gourinath, S. | | Deposit date: | 2017-04-13 | | Release date: | 2017-08-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition
Acta Crystallogr D Struct Biol, 73, 2017
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6SDF
 | | N-terminal SH3 domain of Grb2 protein | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Growth factor receptor-bound protein 2 | | Authors: | Bolgov, A.A, Korban, S.A, Luzik, D.A, Rogacheva, O.N, Zhemkov, V.A, Kim, M, Skrynnikov, N.R, Bezprozvanny, I.B. | | Deposit date: | 2019-07-26 | | Release date: | 2020-01-29 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the SH3 domain of growth factor receptor-bound protein 2.
Acta Crystallogr.,Sect.F, 76, 2020
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7Y4N
 | | Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos | | Descriptor: | Growth factor receptor-bound protein 2 | | Authors: | Pooppadi, M.S, Ikeya, T, Sugasawa, H, Watanabe, R, Mishima, M, Inomata, K, Ito, Y. | | Deposit date: | 2022-06-15 | | Release date: | 2022-08-31 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos.
Biochem.Biophys.Res.Commun., 625, 2022
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6IPZ
 | | Fyn SH3 domain R96W mutant, crystallized with 18-crown-6 | | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Tyrosine-protein kinase Fyn | | Authors: | Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F. | | Deposit date: | 2018-11-05 | | Release date: | 2018-11-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.576 Å) | | Cite: | Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
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