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2IIM

SH3 Domain of Human Lck

Summary for 2IIM
Entry DOI10.2210/pdb2iim/pdb
Related1LCK
DescriptorProto-oncogene tyrosine-protein kinase LCK, ZINC ION, CALCIUM ION, ... (5 entities in total)
Functional Keywordsbeta-barrels, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P06239
Total number of polymer chains1
Total formula weight7194.29
Authors
Romir, J.,Egerer-Sieber, C.,Muller, Y.A. (deposition date: 2006-09-28, release date: 2006-11-07, Last modification date: 2023-08-30)
Primary citationRomir, J.,Lilie, H.,Egerer-Sieber, C.,Bauer, F.,Sticht, H.,Muller, Y.A.
Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs.
J.Mol.Biol., 365:1417-1428, 2007
Cited by
PubMed: 17118402
DOI: 10.1016/j.jmb.2006.10.058
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1 Å)
Structure validation

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