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8I2L
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E. coli tryptophanyl-tRNA synthetase bound with a chemical fragment at the dimerization interface
Descriptor: 1,2-ETHANEDIOL, CHLORZOXAZONE, SULFATE ION, ...
Authors:Xiang, M, Zhou, H.
Deposit date:2023-01-14
Release date:2023-04-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening.
Nucleic Acids Res., 51, 2023
6D9L
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Ternary RsAgo Complex with Guide RNA and Target DNA Containing G-A Non-canonical Pair
Descriptor: DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*AP*GP*CP*AP*GP*TP*AP*AP*C)-3'), MAGNESIUM ION, RNA (5'-R(P*UP*UP*AP*CP*UP*GP*CP*GP*CP*AP*GP*GP*UP*GP*AP*CP*GP*A)-3'), ...
Authors:Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J.
Deposit date:2018-04-30
Release date:2018-07-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
3CGR
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X-ray structure containing the pseudouridylated U2 snRNA and intron branch site consensus sequences
Descriptor: RNA (5'-R(*CP*GP*CP*AP*CP*UP*AP*AP*CP*CP*GP*CP*G)-3'), RNA (5'-R(*GP*CP*GP*CP*GP*GP*(PSU)P*AP*GP*UP*GP*C)-3'), SULFATE ION
Authors:Lin, Y, Kielkopf, C.L.
Deposit date:2008-03-06
Release date:2008-07-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008
2R93
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Elongation complex of RNA polymerase II with a hepatitis delta virus-derived RNA stem loop
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Lehmann, E, Brueckner, F, Cramer, P.
Deposit date:2007-09-12
Release date:2007-11-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4 Å)
Cite:Molecular basis of RNA-dependent RNA polymerase II activity.
Nature, 450, 2007
6D9K
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BU of 6d9k by Molmil
Ternary RsAgo Complex with Guide RNA and Target DNA Containing A-G Non-canonical Pair
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*GP*GP*CP*AP*GP*TP*AP*AP*C)-3'), ...
Authors:Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J.
Deposit date:2018-04-30
Release date:2018-07-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018
8GKH
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Structure of the Spizellomyces punctatus Fanzor (SpuFz) in complex with omega RNA and target DNA
Descriptor: DNA (35-MER), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), MAGNESIUM ION, ...
Authors:Xu, P, Saito, M, Zhang, F.
Deposit date:2023-03-19
Release date:2023-07-05
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Fanzor is a eukaryotic programmable RNA-guided endonuclease.
Nature, 620, 2023
2R92
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Elongation complex of RNA polymerase II with artificial RdRP scaffold
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Lehmann, E, Brueckner, F, Cramer, P.
Deposit date:2007-09-12
Release date:2007-11-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Molecular basis of RNA-dependent RNA polymerase II activity.
Nature, 450, 2007
3CGQ
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X-ray structure of a pseudouridine-containing yeast spliceosomal U2 snRNA-intron branch site duplex
Descriptor: RNA (5'-R(*CP*GP*CP*UP*AP*CP*UP*AP*AP*CP*GP*CP*G)-3'), RNA (5'-R(*GP*CP*GP*CP*GP*(PSU)P*AP*GP*UP*AP*GP*C)-3'), SULFATE ION
Authors:Lin, Y, Kielkopf, C.L.
Deposit date:2008-03-06
Release date:2008-07-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008
7L1T
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BU of 7l1t by Molmil
Crystal structure of human holo SepSecS
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION
Authors:Puppala, A, Castillo Suchkou, J, Simonovic, M.
Deposit date:2020-12-15
Release date:2022-02-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans.
Nucleic Acids Res., 2023
2JXV
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BU of 2jxv by Molmil
Solution structure of a let-7 miRNA:lin-41 mRNA complex from C. elegans
Descriptor: RNA (33-MER)
Authors:Cevec, M, Thibaudeau, C, Plavec, J.
Deposit date:2007-11-30
Release date:2008-04-29
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of a let-7 miRNA:lin-41 mRNA complex from C. elegans.
Nucleic Acids Res., 36, 2008
1FHK
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BU of 1fhk by Molmil
NMR STRUCTURE OF THE 690 LOOP OF 16 S RRNA OF E. COLI
Descriptor: RNA (5'-R(*GP*GP*CP*GP*GP*UP*GP*AP*AP*AP*UP*GP*CP*C)-3')
Authors:Morosyuk, S.V, Cunningham, P.R, SantaLucia Jr, J.
Deposit date:2000-08-01
Release date:2001-03-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and function of the conserved 690 hairpin in Escherichia coli 16 S ribosomal RNA. II. NMR solution structure.
J.Mol.Biol., 307, 2001
7EL8
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BU of 7el8 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase
Descriptor: Tryptophan--tRNA ligase
Authors:Xu, M, Chen, S.
Deposit date:2021-04-09
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
2CWO
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BU of 2cwo by Molmil
Crystal structure of RNA silencing suppressor p21 from Beet Yellows Virus
Descriptor: RNA silencing suppressor
Authors:Ye, K, Patel, D.J.
Deposit date:2005-06-22
Release date:2005-10-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:RNA Silencing Suppressor p21 of Beet Yellows Virus Forms an RNA Binding Octameric Ring Structure
STRUCTURE, 13, 2005
2GJW
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BU of 2gjw by Molmil
RNA Recognition and Cleavage by an Splicing Endonuclease
Descriptor: 5'-R(*AP*GP*GP*UP*CP*GP*C)-3', 5'-R(*GP*CP*GP*AP*CP*CP*GP*AP*CP*CP*AP*(DU)P*AP*GP*CP*UP*GP*CP*A)-3', 5'-R(*UP*GP*CP*AP*GP*CP*GP*GP*UP*CP*AP*(A23))-3', ...
Authors:Xue, S, Calvin, K, Li, H.
Deposit date:2006-03-31
Release date:2006-09-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:RNA Recognition and Cleavage by an Splicing Endonuclease
Science, 312, 2006
1U2A
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BU of 1u2a by Molmil
STEM LOOP IIA FROM U2SNRNA OF SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: RNA (5'-R(P*GP*GP*UP*CP*AP*GP*UP*GP*UP*AP*AP*CP*AP*AP*CP*UP*GP*AP*CP*C)-3')
Authors:Stallings, S.C, Moore, P.B.
Deposit date:1997-08-19
Release date:1998-03-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of an essential splicing element: stem loop IIa from yeast U2 snRNA.
Structure, 5, 1997
3B0V
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BU of 3b0v by Molmil
tRNA-dihydrouridine synthase from Thermus thermophilus in complex with tRNA
Descriptor: FLAVIN MONONUCLEOTIDE, tRNA, tRNA-dihydrouridine synthase
Authors:Yu, F, Tanaka, Y, Yamashita, K, Nakamura, A, Yao, M, Tanaka, I.
Deposit date:2011-06-14
Release date:2011-12-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Molecular basis of dihydrouridine formation on tRNA
Proc.Natl.Acad.Sci.USA, 108, 2011
2IZ8
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BU of 2iz8 by Molmil
MS2-RNA HAIRPIN (C-7) COMPLEX
Descriptor: MS2 COAT PROTEIN, RNA, (5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*CP*UP*CP* AP*CP*CP*CP*AP*UP*GP*U)-3')
Authors:Helgstrand, C, Grahn, E, Stonehouse, N.J, Stockley, P.G, Liljas, L.
Deposit date:2006-07-25
Release date:2006-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Investigating the Structural Basis of Purine Specificity in the Structures of MS2 Coat Protein RNA Translational Operator Hairpins
Nucleic Acids Res., 30, 2002
7KJU
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BU of 7kju by Molmil
Cgi121-tRNA complex
Descriptor: MAGNESIUM ION, RNA (75-MER)
Authors:Ceccarelli, D.F, Beenstock, J, Wan, L.C.K, Sicheri, F.
Deposit date:2020-10-26
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:A substrate binding model for the KEOPS tRNA modifying complex.
Nat Commun, 11, 2020
6SCY
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BU of 6scy by Molmil
U34-tRNA thiolase NcsA from Methanococcus maripaludis with its [4Fe-4S] cluster
Descriptor: IRON/SULFUR CLUSTER, SULFATE ION, ZINC ION, ...
Authors:Bimai, O, Legrand, P, Golinelli-Pimpaneau, B.
Deposit date:2019-07-25
Release date:2020-08-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:The thiolation of uridine 34 in tRNA, which controls protein translation, depends on a [4Fe-4S] cluster in the archaeum Methanococcus maripaludis.
Sci Rep, 13, 2023
2Q1O
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BU of 2q1o by Molmil
Crystal Structure Analysis of the RNA Dodecamer CGC-NF2-AAUUGGCG, with an Incorporated 2,4-Difluorotoluyl Residue (NF2)
Descriptor: RNA (5'-R(*CP*GP*CP*(NF2)P*AP*AP*UP*UP*GP*GP*CP*G)-3')
Authors:Li, F, Pallan, P.S.
Deposit date:2007-05-25
Release date:2007-10-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.
Nucleic Acids Res., 35, 2007
7PJH
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BU of 7pjh by Molmil
Crystal structure of the human spliceosomal maturation factor AAR2 bound to the RNAse H domain of PRPF8
Descriptor: Pre-mRNA-processing-splicing factor 8, Protein AAR2 homolog
Authors:Preussner, M, Santos, K, Heroven, A.C, Alles, J, Heyd, F, Wahl, M.C, Weber, G.
Deposit date:2021-08-24
Release date:2022-11-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and functional investigation of the human snRNP assembly factor AAR2 in complex with the RNase H-like domain of PRPF8.
Acta Crystallogr D Struct Biol, 78, 2022
1EFS
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BU of 1efs by Molmil
CONFORMATION OF A DNA-RNA HYBRID
Descriptor: DNA (5'-D(*GP*AP*GP*AP*GP*GP*AP*AP*GP*AP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*UP*CP*UP*UP*CP*CP*UP*CP*UP*C)-3')
Authors:Larue, V, Hantz, E.
Deposit date:2000-02-10
Release date:2000-03-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution conformation of an RNA--DNA hybrid duplex containing a pyrimidine RNA strand and a purine DNA strand.
Int.J.Biol.Macromol., 28, 2001
1ESH
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BU of 1esh by Molmil
THE SOLUTION STRUCTURE OF THE STEM LOOP C 5'AUA3' TRILOOP OF BROME MOSAIC VIRUS (+) STRAND RNA
Descriptor: RNA (5'-R(*GP*GP*UP*GP*CP*AP*UP*AP*GP*CP*AP*CP*C)-3')
Authors:Kim, C.-H, Kao, C.C, Tinoco Jr, I.
Deposit date:2000-04-10
Release date:2000-04-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:RNA motifs that determine specificity between a viral replicase and its promoter.
Nat.Struct.Biol., 7, 2000
1M82
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SOLUTION STRUCTURE OF THE COMPLEMENTARY RNA PROMOTER OF INFLUENZA A VIRUS
Descriptor: RNA (25-MER): THE COMPLEMENTARY RNA PROMOTER OF INFLUENZA A VIRUS
Authors:Park, C.-J, Bae, S.-H, Lee, M.-K, Varani, G, Choi, B.-S.
Deposit date:2002-07-24
Release date:2003-06-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the influenza A virus cRNA promoter: implications for differential recognition of viral promoter structures by RNA-dependent RNA polymerase
NUCLEIC ACIDS RES., 31, 2003
2MF0
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BU of 2mf0 by Molmil
Structural basis of the non-coding RNA RsmZ acting as protein sponge: Conformer L of RsmZ(1-72)/RsmE(dimer) 1to3 complex
Descriptor: Carbon storage regulator homolog, RNA_(72-MER)
Authors:Duss, O, Michel, E, Yulikov, M, Schubert, M, Jeschke, G, Allain, F.H.-T.
Deposit date:2013-10-02
Release date:2014-05-21
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis of the non-coding RNA RsmZ acting as a protein sponge.
Nature, 509, 2014

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