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4DQV
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Crystal structure of reductase (R) domain of non-ribosomal peptide synthetase from Mycobacterium tuberculosis
Descriptor: PROBABLE PEPTIDE SYNTHETASE NRP (PEPTIDE SYNTHASE)
Authors:Haque, A.S, Panjikar, S, Sankaranarayanan, R.
Deposit date:2012-02-16
Release date:2012-06-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases.
Proc.Natl.Acad.Sci.USA, 109, 2012
1YLK
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Crystal Structure of Rv1284 from Mycobacterium tuberculosis in Complex with Thiocyanate
Descriptor: Hypothetical protein Rv1284/MT1322, THIOCYANATE ION, ZINC ION
Authors:Covarrubias, A.S, Larsson, A.M, Hogbom, M, Lindberg, J, Bergfors, T, Bjorkelid, C, Mowbray, S.L, Unge, T, Jones, T.A, Structural Proteomics in Europe (SPINE)
Deposit date:2005-01-19
Release date:2005-03-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of carbonic anhydrases from Mycobacterium tuberculosis.
J.Biol.Chem., 280, 2005
2WZT
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Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form
Descriptor: ALDO-KETO REDUCTASE
Authors:Scoble, J, McAlister, A.D, Fulton, Z, Troy, S, Byres, E, Vivian, J.P, Brammananth, R, Wilce, M.C.J, Le Nours, J, Zaker-Tabrizi, L, Coppel, R.L, Crellin, P.K, Rossjohn, J, Beddoe, T.
Deposit date:2009-12-03
Release date:2010-02-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure and Comparative Functional Analyses of a Mycobacterium Aldo-Keto Reductase.
J.Mol.Biol., 398, 2010
4NXI
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Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Uncharacterized protein
Authors:Albesa-Jove, D, Urresti, S, Comino, N, Guerin, M.E.
Deposit date:2013-12-09
Release date:2014-10-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014
3ZBY
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Ligand-free structure of CYP142 from Mycobacterium smegmatis
Descriptor: 1,2-ETHANEDIOL, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), P450 HEME-THIOLATE PROTEIN, ...
Authors:Garcia-Fernandez, E, Frank, D.J, Galan, B, Kells, P.M, Podust, L.M, Garcia, J.L, Ortiz de Montellano, P.R.
Deposit date:2012-11-13
Release date:2013-02-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A Highly Conserved Mycobacterial Cholesterol Catabolic Pathway.
Environ.Microbiol., 15, 2013
2WZM
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Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form
Descriptor: ALDO-KETO REDUCTASE, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
Authors:Scoble, J, McAlister, A.D, Fulton, Z, Troy, S, Byres, E, Vivian, J.P, Brammananth, R, Wilce, M.C.J, Le Nours, J, Zaker-Tabrizi, L, Coppel, R.L, Crellin, P.K, Rossjohn, J, Beddoe, T.
Deposit date:2009-11-30
Release date:2010-02-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal Structure and Comparative Functional Analyses of a Mycobacterium Aldo-Keto Reductase.
J.Mol.Biol., 398, 2010
3ZO9
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The structure of Trehalose Synthase (TreS) of Mycobacterium smegmatis
Descriptor: CALCIUM ION, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Caner, S, Nguyen, N, Aguda, A, Zhang, R, Pan, Y.T, Withers, S.G, Brayer, G.D.
Deposit date:2013-02-21
Release date:2013-07-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:The Structure of the Mycobacterium Smegmatis Trehalose Synthase Reveals an Unusual Active Site Configuration and Acarbose-Binding Mode.
Glycobiology, 23, 2013
1YM3
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Crystal Structure of carbonic anhydrase RV3588c from Mycobacterium tuberculosis
Descriptor: CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), MAGNESIUM ION, ZINC ION
Authors:Covarrubias, A.S, Larsson, A.M, Hogbom, M, Lindberg, J, Bergfors, T, Bjorkelid, C, Mowbray, S.L, Unge, T, Jones, T.A, Structural Proteomics in Europe (SPINE)
Deposit date:2005-01-20
Release date:2005-03-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and function of carbonic anhydrases from Mycobacterium tuberculosis.
J.Biol.Chem., 280, 2005
2BM5
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The Structure of MfpA (Rv3361c, P21 Crystal form). The Pentapeptide Repeat Protein from Mycobacterium tuberculosis Folds as A Right- handed Quadrilateral Beta-helix.
Descriptor: PENTAPEPTIDE REPEAT FAMILY PROTEIN, SULFATE ION
Authors:Hegde, S.S, Vetting, M.W, Roderick, S.L, Mitchenall, L.A, Maxwell, A, Takiff, H.E, Blanchard, J.S.
Deposit date:2005-03-09
Release date:2005-06-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Fluroquinolone Resistance Protein from Mycobacterium Tuberculosis that Mimics DNA
Science, 308, 2005
4JMX
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Structure of LD transpeptidase LdtMt1 in complex with imipenem
Descriptor: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Probable L,D-transpeptidase LdtA
Authors:Correale, S, Ruggiero, A, Capparelli, R, Pedone, E, Berisio, R.
Deposit date:2013-03-14
Release date:2013-10-23
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structures of free and inhibited forms of the L,D-transpeptidase LdtMt1 from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 69, 2013
2IRU
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Crystal Structure of the Polymerase Domain from Mycobacterium tuberculosis Ligase D
Descriptor: Putative DNA ligase-like protein Rv0938/MT0965
Authors:Brissett, N.C, Pitcher, R.S, Doherty, A.J.
Deposit date:2006-10-16
Release date:2007-01-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and function of a mycobacterial NHEJ DNA repair polymerase.
J.Mol.Biol., 366, 2007
4APY
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Ethylene glycol-bound form of P450 CYP125A3 from Mycobacterium smegmatis
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, P450 HEME-THIOLATE PROTEIN, ...
Authors:Frank, D.J, Garcia Fernandez, E, Kells, P.M, Garcia Lopez, J.L, Podust, L.M, Ortiz de Montellano, P.R.
Deposit date:2012-04-09
Release date:2013-02-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Highly Conserved Mycobacterial Cholesterol Catabolic Pathway.
Environ.Microbiol., 15, 2013
5E7Z
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BU of 5e7z by Molmil
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis in complex with D/L-tryptophan and D-phenylalanine
Descriptor: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase, D-PHENYLALANINE, D-TRYPTOPHAN, ...
Authors:Reichau, S, Jiao, W, Parker, E.J.
Deposit date:2015-10-13
Release date:2016-06-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using -Amino Acids.
Plos One, 11, 2016
1Y3H
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Crystal Structure of Inorganic Polyphosphate/ATP-NAD kinase from Mycobacterium tuberculosis
Descriptor: Inorganic polyphosphate/ATP-NAD kinase
Authors:Mori, S, Yamasaki, M, Maruyama, Y, Momma, K, kawai, S, Hashimoto, W, Mikami, B, Murata, K.
Deposit date:2004-11-24
Release date:2005-01-18
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:NAD-binding mode and the significance of intersubunit contact revealed by the crystal structure of Mycobacterium tuberculosis NAD kinase-NAD complex
BIOCHEM.BIOPHYS.RES.COMMUN., 327, 2005
7WIK
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BU of 7wik by Molmil
Crystal structure of oligoribonuclease of Mycobacterium smegmatis mc2 155
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Badhwar, P, Taneja, B.
Deposit date:2022-01-03
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Three-dimensional structure of a mycobacterial oligoribonuclease reveals a unique C-terminal tail that stabilizes the homodimer.
J.Biol.Chem., 298, 2022
2A7Y
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Solution Structure of the Conserved Hypothetical Protein Rv2302 from the Bacterium Mycobacterium tuberculosis
Descriptor: Hypothetical protein Rv2302/MT2359
Authors:Buchko, G.W, Kim, C.-Y, Terwilliger, T.C, Kennedy, M.A, TB Structural Genomics Consortium (TBSGC)
Deposit date:2005-07-06
Release date:2005-08-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the conserved hypothetical protein Rv2302 from Mycobacterium tuberculosis.
J.Bacteriol., 188, 2006
2A15
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X-ray Crystal Structure of RV0760 from Mycobacterium Tuberculosis at 1.68 Angstrom Resolution
Descriptor: HYPOTHETICAL PROTEIN Rv0760c, NICOTINAMIDE
Authors:Garen, C.R, Cherney, M.M, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
Deposit date:2005-06-17
Release date:2005-10-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase
Biochim.Biophys.Acta, 1784, 2008
4B55
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Crystal Structure of the Covalent Adduct Formed between Mycobacterium marinum Aryalamine N-acetyltransferase and Phenyl vinyl ketone a derivative of Piperidinols
Descriptor: 3-hydroxy-1-phenylpropan-1-one, ARYLAMINE N-ACETYLTRANSFERASE NAT
Authors:Abuhammad, A, Fullam, E, Lowe, E.D, Staunton, D, Kawamura, A, Westwood, I.M, Bhakta, S, Garner, A.C, Wilson, D.L, Seden, P.T, Davies, S.G, Russell, A.J, Garman, E.F, Sim, E.
Deposit date:2012-08-02
Release date:2013-01-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Piperidinols that Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages.
Plos One, 7, 2012
3E4W
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Crystal structure of a 33kDa catalase-related protein from Mycobacterium avium subsp. paratuberculosis. P2(1)2(1)2(1) crystal form.
Descriptor: GLYCEROL, HEXANE-1,6-DIOL, PHOSPHATE ION, ...
Authors:Pakhomova, S, Newcomer, M.E.
Deposit date:2008-08-12
Release date:2009-08-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure and peroxidase activity of a 33-kDa catalase-related protein from Mycobacterium avium ssp. paratuberculosis.
Protein Sci., 18, 2009
2I6Y
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Structure and Mechanism of Mycobacterium tuberculosis Salicylate Synthase, MbtI
Descriptor: Anthranilate synthase component I, putative
Authors:Zwahlen, J, Subramaniapillai, K, Zhou, R, Kisker, C, Tonge, P.J.
Deposit date:2006-08-29
Release date:2007-06-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
Biochemistry, 46, 2007
2FP2
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Secreted Chorismate Mutase from Mycobacterium tuberculosis
Descriptor: 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, Chorismate mutase
Authors:Okvist, M, Dey, R, Sasso, S, Grahn, E, Kast, P, Krengel, U.
Deposit date:2006-01-15
Release date:2006-03-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:1.6A Crystal Structure of the Secreted Chorismate Mutase from Mycobacterium tuberculosis: Novel Fold Topology Revealed
J.Mol.Biol., 357, 2006
1ZJ8
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BU of 1zj8 by Molmil
Structure of Mycobacterium tuberculosis NirA protein
Descriptor: CHLORIDE ION, IRON/SULFUR CLUSTER, Probable ferredoxin-dependent nitrite reductase NirA, ...
Authors:Schnell, R, Sandalova, T, Hellman, U, Lindqvist, Y, Schneider, G, Structural Proteomics in Europe (SPINE)
Deposit date:2005-04-28
Release date:2005-05-31
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Siroheme- and [Fe4-S4]-dependent NirA from Mycobacterium tuberculosis Is a Sulfite Reductase with a Covalent Cys-Tyr Bond in the Active Site
J.Biol.Chem., 280, 2005
4I0X
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Crystal structure of the Mycobacterum abscessus EsxEF (Mab_3112-Mab_3113) complex
Descriptor: BETA-MERCAPTOETHANOL, ESAT-6-like protein MAB_3112, ESAT-6-like protein MAB_3113, ...
Authors:Arbing, M.A, Chan, S, Lu, J, Kuo, E, Harris, L, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC)
Deposit date:2012-11-19
Release date:2013-01-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.956 Å)
Cite:Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
2F6L
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X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis
Descriptor: Chorismate mutase
Authors:Kim, S.K, Howard, A.J, Gilliland, G.L, Reddy, P.T, Ladner, J.E.
Deposit date:2005-11-29
Release date:2005-12-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids.
J.Bacteriol., 188, 2006
2AQ6
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X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 1.7 a resolution
Descriptor: PYRIDOXAL-5'-PHOSPHATE, PYRIDOXINE 5'-PHOSPHATE OXIDASE
Authors:Biswal, B.K, Cherney, M.M, Wang, M, Garen, C, James, M.N, TB Structural Genomics Consortium (TBSGC)
Deposit date:2005-08-17
Release date:2005-08-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate.
Acta Crystallogr.,Sect.D, 61, 2005

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