3CSO
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![BU of 3cso by Molmil](/molmil-images/mine/3cso) | HCV Polymerase in complex with a 1,5 Benzodiazepine inhibitor | Descriptor: | (11S)-10-acetyl-11-[4-(benzyloxy)-3-chlorophenyl]-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one, RNA-directed RNA polymerase | Authors: | Nyanguile, O. | Deposit date: | 2008-04-10 | Release date: | 2009-04-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | 1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors. Antimicrob.Agents Chemother., 52, 2008
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3BHV
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![BU of 3bhv by Molmil](/molmil-images/mine/3bhv) | Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor variolin B | Descriptor: | 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol, Cell division protein kinase 2, Cyclin-A2, ... | Authors: | Echalier, A, Bettayeb, K, Ferandin, Y, Lozach, O, Clement, M, Valette, A, Liger, F, Marquet, B, Morris, J.C, Endicott, J.A, Joseph, B, Meijer, L. | Deposit date: | 2007-11-29 | Release date: | 2008-02-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases Cancer Res., 67, 2007
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1YLG
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![BU of 1ylg by Molmil](/molmil-images/mine/1ylg) | NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor | Descriptor: | apolipoprotein B mRNA | Authors: | Maris, C, Masse, J, Allain, F.H, Chester, A, Navaratnam, N. | Deposit date: | 2005-01-19 | Release date: | 2005-02-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor. Rna, 11, 2005
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2LLL
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![BU of 2lll by Molmil](/molmil-images/mine/2lll) | Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A | Descriptor: | Lamin-B2 | Authors: | Lemak, A, Yee, A, Houliston, S, Garcia, M, Xu, C, Min, J, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC), Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS) | Deposit date: | 2011-11-11 | Release date: | 2011-12-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR solution structure of c-terminal globular domain of human Lamin-B2 To be Published
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2QDQ
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![BU of 2qdq by Molmil](/molmil-images/mine/2qdq) | Crystal structure of the talin dimerisation domain | Descriptor: | Talin-1 | Authors: | Gingras, A.R, Putz, N.S.M, Bate, N, Barsukov, I.L, Critchley, D.R.C. | Deposit date: | 2007-06-21 | Release date: | 2008-01-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of the C-terminal actin-binding domain of talin. Embo J., 27, 2008
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2RSY
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![BU of 2rsy by Molmil](/molmil-images/mine/2rsy) | Solution structure of the SH2 domain of Csk in complex with a phosphopeptide from Cbp | Descriptor: | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Tyrosine-protein kinase CSK | Authors: | Tanaka, H, Akagi, K, Oneyama, C, Tanaka, M, Sasaki, Y, Kanou, T, Lee, Y, Yokogawa, D, Debenecker, M, Nakagawa, A, Okada, M, Ikegami, T. | Deposit date: | 2012-09-10 | Release date: | 2013-04-10 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains. J.Biol.Chem., 288, 2013
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1I5U
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![BU of 1i5u by Molmil](/molmil-images/mine/1i5u) | SOLUTION STRUCTURE OF CYTOCHROME B5 TRIPLE MUTANT (E48A/E56A/D60A) | Descriptor: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Qian, C, Yao, Y, Tang, W, Wang, J, Zhongxian, H. | Deposit date: | 2001-02-28 | Release date: | 2001-03-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Effects of charged amino-acid mutation on the solution structure of cytochrome b(5) and binding between cytochrome b(5) and cytochrome c. Protein Sci., 10, 2001
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1FI3
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![BU of 1fi3 by Molmil](/molmil-images/mine/1fi3) | |
2FS4
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![BU of 2fs4 by Molmil](/molmil-images/mine/2fs4) | Ketopiperazine-Based Renin Inhibitors: Optimization of the C ring | Descriptor: | (6R)-6-({[1-(3-HYDROXYPROPYL)-1,7-DIHYDROQUINOLIN-7-YL]OXY}METHYL)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)PIPERAZIN-2-ONE, Renin | Authors: | Holsworth, D.D, Cai, C, Cheng, X.-M, Cody, W.L, Downing, D.M, Erasga, N, Lee, C, Powell, N.A, Edmunds, J.J, Stier, M, Jalaie, M, Zhang, E, McConnell, P, Ryan, M.J, Bryant, J, Li, T, Kasani, A, Hall, E, Subedi, R, Rahim, M, Maiti, S. | Deposit date: | 2006-01-20 | Release date: | 2006-06-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring BIOORG.MED.CHEM.LETT., 16, 2006
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3QIU
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![BU of 3qiu by Molmil](/molmil-images/mine/3qiu) | Crystal structure of the 226 TCR in complex with MCC/I-Ek | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K alpha chain, ... | Authors: | Kruse, A.C, Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C. | Deposit date: | 2011-01-27 | Release date: | 2011-04-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k). J.Immunol., 186, 2011
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3BGE
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![BU of 3bge by Molmil](/molmil-images/mine/3bge) | Crystal structure of the C-terminal fragment of AAA+ATPase from Haemophilus influenzae | Descriptor: | Predicted ATPase, SULFATE ION | Authors: | Ramagopal, U.A, Patskovsky, Y, Bonanno, J.B, Meyer, A.J, Toro, R, Freeman, J, Adams, J, Koss, J, Maletic, M, Gheyi, T, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-11-26 | Release date: | 2008-01-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of the C-terminal fragment of AAA+ATPase from Haemophilus influenzae. To be Published
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2PVR
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![BU of 2pvr by Molmil](/molmil-images/mine/2pvr) | Crystal structure of the catalytic subunit of protein kinase CK2 (C-terminal deletion mutant 1-335) in complex with two sulfate ions | Descriptor: | Casein kinase II subunit alpha, catalytic subunit, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Niefind, K, Yde, C.W, Ermakova, I, Issinger, O.-G. | Deposit date: | 2007-05-10 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.605 Å) | Cite: | Evolved to Be Active: Sulfate Ions Define Substrate Recognition Sites of CK2alpha and Emphasise its Exceptional Role within the CMGC Family of Eukaryotic Protein Kinases J.Mol.Biol., 370, 2007
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1GM4
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![BU of 1gm4 by Molmil](/molmil-images/mine/1gm4) | OXIDISED STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 at pH 7.6 | Descriptor: | CYTOCHROME C3, HEME C, SULFATE ION | Authors: | Bento, I, Louro, R, Matias, P.M, Catarino, T, Baptista, A.M, Soares, C.M, Carrondo, M.A, Turner, D.L, Xavier, A.V. | Deposit date: | 2001-09-10 | Release date: | 2002-09-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Conformational Component in the Coupled Transfer of Multiple Electrons and Protons in a Monomeric Tetraheme Cytochrome. J.Biol.Chem., 276, 2001
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1GMB
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![BU of 1gmb by Molmil](/molmil-images/mine/1gmb) | Reduced structure of CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 at pH 7.6 | Descriptor: | CYTOCHROME C3, HEME C, SULFATE ION | Authors: | Bento, I, Louro, R, Matias, P.M, Catarino, T, Baptista, A.M, Soares, C.M, Carrondo, M.A, Turner, D.L, Xavier, A.V. | Deposit date: | 2001-09-12 | Release date: | 2002-09-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conformational Component in the Coupled Transfer of Multiple Electrons and Protons in a Monomeric Tetraheme Cytochrome J.Biol.Chem., 276, 2001
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1Q31
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![BU of 1q31 by Molmil](/molmil-images/mine/1q31) | Crystal Structure of the Tobacco Etch Virus Protease C151A mutant | Descriptor: | BETA-MERCAPTOETHANOL, Nuclear inclusion protein A | Authors: | Nunn, C.M, Djordjevic, S, George, R.R, Urquhart, G.T, Chao, L.H, Tsuchiya, Y. | Deposit date: | 2003-07-28 | Release date: | 2004-11-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site. J.Mol.Biol., 350, 2005
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3PRL
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![BU of 3prl by Molmil](/molmil-images/mine/3prl) | Crystal structure of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Bacillus halodurans C-125 | Descriptor: | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, SULFATE ION | Authors: | Malashkevich, V.N, Toro, R, Seidel, R, Garrett, S, Foti, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2010-11-29 | Release date: | 2010-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Bacillus halodurans C-125 To be Published
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2QW6
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![BU of 2qw6 by Molmil](/molmil-images/mine/2qw6) | Crystal structure of the C-terminal domain of an AAA ATPase from Enterococcus faecium DO | Descriptor: | AAA ATPase, central region | Authors: | Bonanno, J.B, Rutter, M, Bain, K.T, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-08-09 | Release date: | 2007-08-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the C-terminal domain of an AAA ATPase from Enterococcus faecium DO. To be Published
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2K3V
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![BU of 2k3v by Molmil](/molmil-images/mine/2k3v) | Solution Structure of a Tetrahaem Cytochrome from Shewanella Frigidimarina | Descriptor: | HEME C, Tetraheme cytochrome c-type | Authors: | Paixao, V.B, Turner, D.L, Salgueiro, C.A, Brennan, L, Reid, G.A, Chapman, S.K. | Deposit date: | 2008-05-19 | Release date: | 2009-03-31 | Last modified: | 2019-10-02 | Method: | SOLUTION NMR | Cite: | The solution structure of a tetraheme cytochrome from Shewanella frigidimarina reveals a novel family structural motif Biochemistry, 47, 2008
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2N3K
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![BU of 2n3k by Molmil](/molmil-images/mine/2n3k) | Human Brd4 ET domain in complex with MLV Integrase C-term | Descriptor: | Bromodomain-containing protein 4, MLV integrase | Authors: | Crowe, B.L, Foster, M.P. | Deposit date: | 2015-06-03 | Release date: | 2016-03-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the Brd4 ET domain bound to a C-terminal motif from gamma-retroviral integrases reveals a conserved mechanism of interaction. Proc.Natl.Acad.Sci.USA, 113, 2016
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3U6H
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![BU of 3u6h by Molmil](/molmil-images/mine/3u6h) | Crystal structure of c-Met in complex with pyrazolone inhibitor 26 | Descriptor: | Hepatocyte growth factor receptor, N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide | Authors: | Bellon, S.F, Whittington, D.A, Long, A.L. | Deposit date: | 2011-10-12 | Release date: | 2012-02-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives. J.Med.Chem., 55, 2012
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1J8I
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![BU of 1j8i by Molmil](/molmil-images/mine/1j8i) | Solution Structure of Human Lymphotactin | Descriptor: | Lymphotactin | Authors: | Kuloglu, E.S, McCaslin, D.R, Markley, J.L, Pauza, C.D, Volkman, B.F. | Deposit date: | 2001-05-21 | Release date: | 2001-10-24 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Monomeric solution structure of the prototypical 'C' chemokine lymphotactin. Biochemistry, 40, 2001
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3RHH
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![BU of 3rhh by Molmil](/molmil-images/mine/3rhh) | Crystal structure of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Bacillus halodurans C-125 complexed with NADP | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, SULFATE ION | Authors: | Malashkevich, V.N, Toro, R, Seidel, R, Garrett, S, Foti, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2011-04-11 | Release date: | 2011-05-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Bacillus halodurans C-125 complexed with NADP To be Published
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4LKU
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![BU of 4lku by Molmil](/molmil-images/mine/4lku) | |
5CON
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![BU of 5con by Molmil](/molmil-images/mine/5con) | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-015 | Descriptor: | (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, HIV-1 protease | Authors: | Yedidi, R.S, Hayashi, H, Aoki, M, Das, D, Ghosh, A.K, Mitsuya, H. | Deposit date: | 2015-07-20 | Release date: | 2016-01-13 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir. J.Virol., 90, 2015
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2L17
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![BU of 2l17 by Molmil](/molmil-images/mine/2l17) | An arsenate reductase in the reduced state | Descriptor: | Arsenate reductase | Authors: | Yu, C, Xia, B, Jin, C. | Deposit date: | 2010-07-26 | Release date: | 2011-04-13 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | (1)H, (13)C and (15)N resonance assignments of the arsenate reductase from Synechocystis sp. strain PCC 6803 Biomol.Nmr Assign., 5, 2011
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