2MKP
N domain of cardiac troponin C bound to the switch fragment of fast skeletal troponin I at pH 6
Summary for 2MKP
Entry DOI | 10.2210/pdb2mkp/pdb |
NMR Information | BMRB: 19789 |
Descriptor | Troponin C, slow skeletal and cardiac muscles, Troponin I, fast skeletal muscle, CALCIUM ION (3 entities in total) |
Functional Keywords | troponin c, troponin i, ef-hand, calcium binding, ischemia, metal binding protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 11972.67 |
Authors | Robertson, I.M.,Pineda-Sanabria, S.E.,Holmes, P.C.,Sykes, B.D. (deposition date: 2014-02-11, release date: 2014-02-26, Last modification date: 2024-05-01) |
Primary citation | Robertson, I.M.,Pineda-Sanabria, S.E.,Holmes, P.C.,Sykes, B.D. Conformation of the critical pH sensitive region of troponin depends upon a single residue in troponin I. Arch.Biochem.Biophys., 552-553:40-49, 2014 Cited by PubMed: 24333682DOI: 10.1016/j.abb.2013.12.003 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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