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2MKP

N domain of cardiac troponin C bound to the switch fragment of fast skeletal troponin I at pH 6

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
Troponin C, slow skeletal and cardiac musclespolymer8910070.31UniProt (P63316)
Pfam (PF13833)
Homo sapiens (human)TN-C
2B
(I)
Troponin I, fast skeletal musclepolymer171862.31UniProt (P48788)Homo sapiens (human)Troponin I, fast-twitch isoform
3C
(C)
CALCIUM IONnon-polymer40.11Chemie (CA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight11932.6
Non-Polymers*Number of molecules1
Total formula weight40.1
All*Total formula weight11972.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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