1I6H
| RNA POLYMERASE II ELONGATION COMPLEX | Descriptor: | 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3', 5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, ... | Authors: | Gnatt, A.L, Cramer, P, Kornberg, R.D. | Deposit date: | 2001-03-02 | Release date: | 2001-04-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution. Science, 292, 2001
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3M4O
| RNA polymerase II elongation complex B | Descriptor: | DNA (28-MER), DNA (5'-D(P*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Wang, D, Zhu, G, Huang, X, Lippard, S.J. | Deposit date: | 2010-03-11 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.57 Å) | Cite: | X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc.Natl.Acad.Sci.USA, 107, 2010
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3M3Y
| RNA polymerase II elongation complex C | Descriptor: | DNA (28-MER), DNA (5'-D(*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Wang, D, Zhu, G, Huang, X, Lippard, S.J. | Deposit date: | 2010-03-10 | Release date: | 2010-05-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc.Natl.Acad.Sci.USA, 107, 2010
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1I3Q
| RNA POLYMERASE II CRYSTAL FORM I AT 3.1 A RESOLUTION | Descriptor: | DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ... | Authors: | Cramer, P, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2001-02-15 | Release date: | 2001-04-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution. Science, 292, 2001
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1I50
| RNA POLYMERASE II CRYSTAL FORM II AT 2.8 A RESOLUTION | Descriptor: | DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ... | Authors: | Cramer, P, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2001-02-23 | Release date: | 2001-04-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution. Science, 292, 2001
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1R9S
| RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MATCHED NUCLEOTIDE | Descriptor: | DNA strand, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ... | Authors: | Westover, K.D, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2003-10-30 | Release date: | 2004-11-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.25 Å) | Cite: | Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119, 2004
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1R9T
| RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MISMATCHED NUCLEOTIDE | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA nontemplate strand, DNA template strand, ... | Authors: | Westover, K.D, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2003-10-30 | Release date: | 2004-11-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119, 2004
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1SFO
| RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX | Descriptor: | DNA STRAND, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ... | Authors: | Westover, K.D, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2004-02-20 | Release date: | 2004-03-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.61 Å) | Cite: | Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II Science, 303, 2004
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2R93
| Elongation complex of RNA polymerase II with a hepatitis delta virus-derived RNA stem loop | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Lehmann, E, Brueckner, F, Cramer, P. | Deposit date: | 2007-09-12 | Release date: | 2007-11-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Molecular basis of RNA-dependent RNA polymerase II activity. Nature, 450, 2007
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2R92
| Elongation complex of RNA polymerase II with artificial RdRP scaffold | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Lehmann, E, Brueckner, F, Cramer, P. | Deposit date: | 2007-09-12 | Release date: | 2007-11-27 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Molecular basis of RNA-dependent RNA polymerase II activity. Nature, 450, 2007
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8UKU
| RNA polymerase II elongation complex with Fapy-dG lesion with CMP added | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Hou, P, Oh, J, Wang, D. | Deposit date: | 2023-10-15 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
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8UKQ
| RNA polymerase II elongation complex with Fapy-dG lesion in apo state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Hou, P, Oh, J, Wang, D. | Deposit date: | 2023-10-15 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
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8UKR
| RNA polymerase II elongation complex with Fapy-dG lesion soaking with ATP before chemistry | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | Authors: | Hou, P, Oh, J, Wang, D. | Deposit date: | 2023-10-15 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.78 Å) | Cite: | Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
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8UKS
| RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | Authors: | Hou, P, Oh, J, Wang, D. | Deposit date: | 2023-10-15 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
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8UKT
| RNA polymerase II elongation complex with Fapy-dG lesion with AMP added | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Hou, P, Oh, J, Wang, D. | Deposit date: | 2023-10-15 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
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7PY7
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in more-swiveled conformation) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-09 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PYK
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in more-swiveled conformation) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-10 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY5
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (the consensus NusA-NusG-EC) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-09 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY0
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (NusG-EC in more-swiveled conformation) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-08 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY8
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (NusG-EC in less-swiveled conformation) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-09 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY3
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (the consensus NusA-EC) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-08 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY6
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in less-swiveled conformation) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-09 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PY1
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (the consensus NusG-EC) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-08 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7PYJ
| CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in less-swiveled conformation) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Zhu, C, Guo, X, Weixlbaumer, A. | Deposit date: | 2021-10-10 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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1R5U
| RNA POLYMERASE II TFIIB COMPLEX | Descriptor: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... | Authors: | Bushnell, D.A, Westover, K.D, Davis, R, Kornberg, R.D. | Deposit date: | 2003-10-13 | Release date: | 2004-02-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms. Science, 303, 2004
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