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2KQR
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BU of 2kqr by Molmil
Solution structure of the N-terminal domain (residues 1-111) of Brugia malayi asparaginyl-tRNA synthetase
Descriptor: Asparaginyl-tRNA synthetase, cytoplasmic
Authors:Volkman, B.F, Peterson, F.C, Kron, M.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2009-11-16
Release date:2009-12-15
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:A Hybrid Structural Model of the Complete Brugia malayi Cytoplasmic Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 405, 2011
1WNY
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BU of 1wny by Molmil
Isoleucyl-tRNA synthetase editing domain
Descriptor: isoleucyl-trna synthetase
Authors:Fukunaga, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-08-11
Release date:2005-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase
J.Mol.Biol., 359, 2006
4K86
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BU of 4k86 by Molmil
Crystal structure of human prolyl-tRNA synthetase (apo form)
Descriptor: Proline--tRNA ligase, ZINC ION
Authors:Hwang, K.Y, Son, J.H, Lee, E.H.
Deposit date:2013-04-18
Release date:2013-10-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone.
Acta Crystallogr.,Sect.D, 69, 2013
2ZZF
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BU of 2zzf by Molmil
Crystal structure of alanyl-tRNA synthetase without oligomerization domain
Descriptor: Alanyl-tRNA synthetase, ZINC ION
Authors:Sokabe, M, Ose, T, Tokunaga, K, Nakamura, A, Nureki, O, Yao, M, Tanaka, I.
Deposit date:2009-02-10
Release date:2009-07-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of alanyl-tRNA synthetase with editing domain.
Proc.Natl.Acad.Sci.USA, 106, 2009
2ZZE
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BU of 2zze by Molmil
Crystal structure of alanyl-tRNA synthetase without oligomerization domain in lysine-methylated form
Descriptor: Alanyl-tRNA synthetase, ZINC ION
Authors:Sokabe, M, Ose, T, Tokunaga, K, Nakamura, A, Nureki, O, Yao, M, Tanaka, I.
Deposit date:2009-02-10
Release date:2009-07-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:The structure of alanyl-tRNA synthetase with editing domain.
Proc.Natl.Acad.Sci.USA, 106, 2009
3V0R
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BU of 3v0r by Molmil
Crystal structure of Alternaria alternata allergen Alt a 1
Descriptor: 2,5,6-triaminopyrimidin-4-ol, 8-aminooctanoic acid, Major allergen Alt a 1, ...
Authors:Chruszcz, M, Solberg, R, Osinski, T, Chapman, M.D, Minor, W.
Deposit date:2011-12-08
Release date:2012-06-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Alternaria alternata allergen Alt a 1: a unique beta-barrel protein dimer found exclusively in fungi.
J.Allergy Clin.Immunol., 130, 2012
1U0B
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BU of 1u0b by Molmil
Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys
Descriptor: Cysteine--tRNA ligase, ZINC ION, cysteinyl tRNA
Authors:Hauenstein, S, Zhang, C.M, Hou, Y.M, Perona, J.J.
Deposit date:2004-07-13
Release date:2004-11-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Shape-selective RNA recognition by cysteinyl-tRNA synthetase
Nat.Struct.Mol.Biol., 11, 2004
1KRT
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BU of 1krt by Molmil
SOLUTION STRUCTURE OF THE ANTICODON BINDING DOMAIN OF ESCHERICHIA COLI LYSYL-TRNA SYNTHETASE AND STUDIES OF ITS INTERACTIONS WITH TRNA-LYS
Descriptor: LYSYL-TRNA SYNTHETASE (PRODUCT OF LYSS GENE)
Authors:Commans, S, Dardel, F.
Deposit date:1995-06-09
Release date:1995-09-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the anticodon-binding domain of Escherichia coli lysyl-tRNA synthetase and studies of its interaction with tRNA(Lys).
J.Mol.Biol., 253, 1995
4TWA
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BU of 4twa by Molmil
Crystal Structure of Prolyl-tRNA Synthetase (PRS) from Plasmodium falciparum
Descriptor: CHLORIDE ION, Proline--tRNA ligase, SULFATE ION
Authors:Jain, V, Yogavel, M, Sharma, A.
Deposit date:2014-06-30
Release date:2014-08-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase.
J. Struct. Funct. Genomics, 15, 2014
9QMP
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BU of 9qmp by Molmil
E.coli seryl-tRNA synthetase
Descriptor: Serine--tRNA ligase
Authors:Cusack, S.
Deposit date:2025-03-24
Release date:2025-05-14
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:A second class of synthetase structure revealed by X-ray analysis of Escherichia coli seryl-tRNA synthetase at 2.5 A.
Nature, 347, 1990
7EXY
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BU of 7exy by Molmil
T-hairpin structure found in the RNA element involved in the piRNA biogenesis
Descriptor: RNA (5'-R(*UP*UP*GP*GP*UP*UP*UP*GP*AP*UP*UP*CP*CP*AP*AP*G)-3')
Authors:Takase, N, Kawai, G.
Deposit date:2021-05-29
Release date:2022-03-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:T-hairpin structure found in the RNA element involved in piRNA biogenesis.
Rna, 28, 2022
6LDK
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BU of 6ldk by Molmil
Isoleucyl-tRNA synthetase from Candida albicans complexed with a isoleucyl-adenylate
Descriptor: ADENOSINE MONOPHOSPHATE, ISOLEUCINE, Isoleucine--tRNA ligase
Authors:Cho, Y, Chung, S.
Deposit date:2019-11-21
Release date:2020-11-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for the Antibiotic Resistance of Eukaryotic Isoleucyl-tRNA Synthetase.
Mol.Cells, 43, 2020
4UPA
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BU of 4upa by Molmil
Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase in complex with AMPPNP
Descriptor: LYSINE--TRNA LIGASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Bonnefond, L, Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
4UP8
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BU of 4up8 by Molmil
Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase apo form
Descriptor: LYSINE--TRNA LIGASE
Authors:Bonnefond, L, Nureki, O.
Deposit date:2014-06-14
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.896 Å)
Cite:Crystal Structures of Entamoeba Histolytica Lysyl-tRNA Synthetase Reveal Conformational Changes Upon Lysine Binding and a Specific Helix Bundle Domain.
FEBS Lett., 588, 2014
2RKJ
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BU of 2rkj by Molmil
Cocrystal structure of a tyrosyl-tRNA synthetase splicing factor with a group I intron RNA
Descriptor: RNA (238-MER), RNA (5'-R(P*GP*CP*UP*U)-3'), Tyrosyl-tRNA synthetase
Authors:Paukstelis, P.J, Chen, J.-H, Chase, E, Lambowitz, A.M, Golden, B.L.
Deposit date:2007-10-16
Release date:2008-01-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of a tyrosyl-tRNA synthetase splicing factor bound to a group I intron RNA.
Nature, 451, 2008
8C8U
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BU of 8c8u by Molmil
Priestia megaterium mupirocin-resistant isoleucyl-tRNA synthetase 2 complexed with mupirocin
Descriptor: Isoleucine--tRNA ligase, L(+)-TARTARIC ACID, MUPIROCIN, ...
Authors:Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Gruic-Sovulj, I, Ban, N.
Deposit date:2023-01-21
Release date:2023-08-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif.
Nat Commun, 14, 2023
1A9L
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BU of 1a9l by Molmil
SOLUTION STRUCTURE OF A SUBSTRATE FOR THE ARCHAEAL PRE-TRNA SPLICING ENDONUCLEASES: THE BULGE-HELIX-BULGE MOTIF, NMR, 12 STRUCTURES
Descriptor: PRE-TRNA BULGE-HELIX-BULGE MOTIF
Authors:Diener, J.L, Moore, P.B.
Deposit date:1998-04-07
Release date:1998-06-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a substrate for the archaeal pre-tRNA splicing endonucleases: the bulge-helix-bulge motif.
Mol.Cell, 1, 1998
5ONH
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BU of 5onh by Molmil
Quaternary complex of wild type E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation
Descriptor: 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, L-leucyl-tRNA(Leu), ...
Authors:Palencia, A, Cusack, S.
Deposit date:2017-08-03
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase.
J. Mol. Biol., 430, 2018
1KMN
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BU of 1kmn by Molmil
HISTIDYL-TRNA SYNTHETASE COMPLEXED WITH HISTIDINOL AND ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, HISTIDYL-TRNA SYNTHETASE, L-histidinol
Authors:Arnez, J.G, Francklyn, C.S, Moras, D.
Deposit date:1997-05-09
Release date:1997-12-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase.
Proc.Natl.Acad.Sci.USA, 94, 1997
1KMM
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BU of 1kmm by Molmil
HISTIDYL-TRNA SYNTHETASE COMPLEXED WITH HISTIDYL-ADENYLATE
Descriptor: HISTIDYL-ADENOSINE MONOPHOSPHATE, HISTIDYL-TRNA SYNTHETASE
Authors:Arnez, J.G, Francklyn, C.S, Moras, D.
Deposit date:1997-05-09
Release date:1997-12-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase.
Proc.Natl.Acad.Sci.USA, 94, 1997
2I4O
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BU of 2i4o by Molmil
Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2IY5
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BU of 2iy5 by Molmil
PHENYLALANYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS complexed with tRNA and a phenylalanyl-adenylate analog
Descriptor: ADENOSINE-5'-[PHENYLALANINOL-PHOSPHATE], MAGNESIUM ION, PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN, ...
Authors:Moor, N, Kotik-Kogan, O, Tworowski, D, Sukhanova, M, Safro, M.
Deposit date:2006-07-12
Release date:2006-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The crystal structure of the ternary complex of phenylalanyl-tRNA synthetase with tRNAPhe and a phenylalanyl-adenylate analogue reveals a conformational switch of the CCA end.
Biochemistry, 45, 2006
3FOZ
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BU of 3foz by Molmil
Structure of E. coli Isopentenyl-tRNA transferase in complex with E. coli tRNA(Phe)
Descriptor: CALCIUM ION, tRNA delta(2)-isopentenylpyrophosphate transferase, tRNA(Phe)
Authors:Seif, E, Hallberg, B.M.
Deposit date:2009-01-02
Release date:2009-01-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:RNA-Protein Mutually Induced Fit: STRUCTURE OF ESCHERICHIA COLI ISOPENTENYL-tRNA TRANSFERASE IN COMPLEX WITH tRNA(Phe).
J.Biol.Chem., 284, 2009
1B8A
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BU of 1b8a by Molmil
ASPARTYL-TRNA SYNTHETASE
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PROTEIN (ASPARTYL-TRNA SYNTHETASE)
Authors:Schmitt, E, Moulinier, L, Thierry, J.-C, Moras, D.
Deposit date:1999-01-27
Release date:1999-02-02
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of aspartyl-tRNA synthetase from Pyrococcus kodakaraensis KOD: archaeon specificity and catalytic mechanism of adenylate formation.
EMBO J., 17, 1998
8H1C
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BU of 8h1c by Molmil
Cryo-EM structure of Oryza sativa plastid glycyl-tRNA synthetase in complex with two tRNAs (one in tRNA binding state and the other in tRNA locked state)
Descriptor: Glycine--tRNA ligase, tRNA(gly) (74-MER)
Authors:Yu, Z, Wu, Z, Li, Y, Lu, G, Lin, J.
Deposit date:2022-10-02
Release date:2023-04-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase.
Nucleic Acids Res., 51, 2023

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