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2C22
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BU of 2c22 by Molmil
Efficient and High Fidelity Incorporation of dCTP Opposite 7,8- Dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA Polymerase Dpo4
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*C)-3', 5'-D(TP*CP*AP*C 8OGP*GP*AP*AP*TP*CP*CP*TP *TP*CP*CP*CP*CP*C)-3', ...
Authors:Irimia, A, Loukachevitch, L.V, Egli, M.
Deposit date:2005-09-26
Release date:2005-11-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Efficient and High Fidelity Incorporation of Dctp Opposite 7,8-Dihydro-8-Oxodeoxyguanosine by Sulfolobus Solfataricus DNA Polymerase Dpo4
J.Biol.Chem., 281, 2006
2C62
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Crystal Structure of the Human Transcription Cofactor PC4 in Complex with Single-Stranded DNA
Descriptor: 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP *TP*TP*TP*TP*TP*TP*TP*TP*TP*G)-3', ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15, SULFATE ION
Authors:Werten, S, Moras, D.
Deposit date:2005-11-07
Release date:2006-01-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:A Global Transcription Cofactor Bound to Juxtaposed Strands of Unwound DNA
Nat.Struct.Mol.Biol., 13, 2006
1AJ7
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IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY
Descriptor: 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID, IMMUNOGLOBULIN 48G7 FAB (HEAVY CHAIN), IMMUNOGLOBULIN 48G7 FAB (LIGHT CHAIN)
Authors:Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C.
Deposit date:1997-05-15
Release date:1997-11-12
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
2BN2
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CRYSTAL STRUCTURE OF BOVINE NEUROPHYSIN II COMPLEXED WITH THE VASOPRESSIN ANALOGUE PHE-TYR AMIDE
Descriptor: NEUROPHYSIN II, PHENYLALANINE, TYROSINE
Authors:Rose, J.P, Wang, B.C.
Deposit date:1998-12-18
Release date:1999-02-16
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a bovine neurophysin II dipeptide complex at 2.8 A determined from the single-wavelength anomalous scattering signal of an incorporated iodine atom.
Proc.Natl.Acad.Sci.USA, 88, 1991
1AIP
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EF-TU EF-TS COMPLEX FROM THERMUS THERMOPHILUS
Descriptor: ELONGATION FACTOR TS, ELONGATION FACTOR TU
Authors:Wang, Y, Jiang, Y, Meyering-Voss, M, Sprinzl, M, Sigler, P.B.
Deposit date:1997-04-22
Release date:1997-10-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus.
Nat.Struct.Biol., 4, 1997
3VR2
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BU of 3vr2 by Molmil
Crystal structure of nucleotide-free A3B3 complex from Enterococcus hirae V-ATPase [eA3B3]
Descriptor: V-type sodium ATPase catalytic subunit A, V-type sodium ATPase subunit B
Authors:Arai, S, Saijo, S, Suzuki, K, Mizutani, K, Kakinuma, Y, Ishizuka-Katsura, Y, Ohsawa, N, Terada, T, Shirouzu, M, Yokoyama, S, Iwata, S, Yamato, I, Murata, T.
Deposit date:2012-04-03
Release date:2013-01-16
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Rotation mechanism of Enterococcus hirae V(1)-ATPase based on asymmetric crystal structures
Nature, 493, 2013
1AL8
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THREE-DIMENSIONAL STRUCTURE OF GLYCOLATE OXIDASE WITH BOUND ACTIVE-SITE INHIBITORS
Descriptor: 3-DECYL-2,5-DIOXO-4-HYDROXY-3-PYRROLINE, FLAVIN MONONUCLEOTIDE, GLYCOLATE OXIDASE
Authors:Stenberg, K, Lindqvist, Y.
Deposit date:1997-06-12
Release date:1997-09-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-dimensional structures of glycolate oxidase with bound active-site inhibitors.
Protein Sci., 6, 1997
2C6D
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BU of 2c6d by Molmil
Aurora A kinase activated mutant (T287D) in complex with ADPNP
Descriptor: GLYCEROL, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Pauptit, R.A, Pannifer, A.D, Breed, J, McMiken, H.H.J, Rowsell, S, Anderson, M.
Deposit date:2005-11-09
Release date:2006-01-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sar and Inhibitor Complex Structure Determination of a Novel Class of Potent and Specific Aurora Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
1ALN
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BU of 1aln by Molmil
CRYSTAL STRUCTURE OF CYTIDINE DEAMINASE COMPLEXED WITH 3-DEAZACYTIDINE
Descriptor: 3-DEAZACYTIDINE, CYTIDINE DEAMINASE, ZINC ION
Authors:Xiang, S, Carter, C.W.
Deposit date:1997-06-02
Release date:1997-09-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cytidine deaminase complexed to 3-deazacytidine: a "valence buffer" in zinc enzyme catalysis.
Biochemistry, 35, 1996
1AM2
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GYRA INTEIN FROM MYCOBACTERIUM XENOPI
Descriptor: MXE GYRA INTEIN
Authors:Klabunde, T, Sharma, S, Sacchettini, J.C.
Deposit date:1997-06-20
Release date:1998-06-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing.
Nat.Struct.Biol., 5, 1998
2BVE
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BU of 2bve by Molmil
Structure of the N-terminal of Sialoadhesin in complex with 2-Phenyl- Prop5Ac
Descriptor: SIALOADHESIN, benzyl 3,5-dideoxy-5-(propanoylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid
Authors:Zaccai, N.R, May, A.P, Robinson, R.C, Burtnick, L.D, Crocker, P, Brossmer, R, Kelm, S, Jones, E.Y.
Deposit date:2005-06-27
Release date:2006-07-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic and in Silico Analysis of the Sialoside-Binding Characteristics of the Siglec Sialoadhesin.
J.Mol.Biol., 365, 2007
1AMO
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BU of 1amo by Molmil
THREE-DIMENSIONAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE: PROTOTYPE FOR FMN-AND FAD-CONTAINING ENZYMES
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Wang, M, Roberts, D.L, Paschke, R, Shea, T.M, Masters, B.S.S, Kim, J.J.P.
Deposit date:1997-06-17
Release date:1998-06-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes.
Proc.Natl.Acad.Sci.USA, 94, 1997
2BW9
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BU of 2bw9 by Molmil
Laue Structure of L29W MbCO
Descriptor: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Schmidt, M, Nienhaus, K, Pahl, R, Krasselt, A, Anderson, S, Parak, F, Nienhaus, G.U, Srajer, V.
Deposit date:2005-07-13
Release date:2005-07-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Ligand Migration Pathway and Protein Dynamics in Myoglobin: A Time-Resolved Crystallographic Study on L29W Mbco.
Proc.Natl.Acad.Sci.USA, 102, 2005
1A4O
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BU of 1a4o by Molmil
14-3-3 PROTEIN ZETA ISOFORM
Descriptor: 14-3-3 PROTEIN ZETA
Authors:Liu, D, Bienkowska, J, Petosa, C, Collier, R.J, Fu, H, Liddington, R.C.
Deposit date:1998-02-01
Release date:1999-03-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the zeta isoform of the 14-3-3 protein.
Nature, 376, 1995
2BXV
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BU of 2bxv by Molmil
Dual binding mode of a novel series of DHODH inhibitors
Descriptor: 2-({[3-FLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID, ACETATE ION, DIHYDROOROTATE DEHYDROGENASE, ...
Authors:Baumgartner, R, Walloschek, M, Karlik, M, Gotschlich, A, Tasler, S, Mies, J, Leban, J.
Deposit date:2005-07-27
Release date:2006-08-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Dual binding mode of a novel series of DHODH inhibitors.
J. Med. Chem., 49, 2006
1AAC
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BU of 1aac by Molmil
AMICYANIN OXIDIZED, 1.31 ANGSTROMS
Descriptor: AMICYANIN, COPPER (II) ION
Authors:Cunane, L.M, Chen, Z.-W, Durley, R.C.E, Mathews, F.S.
Deposit date:1995-09-07
Release date:1996-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:X-ray structure of the cupredoxin amicyanin, from Paracoccus denitrificans, refined at 1.31 A resolution.
Acta Crystallogr.,Sect.D, 52, 1996
1AKD
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BU of 1akd by Molmil
CYTOCHROME P450CAM FROM PSEUDOMONAS PUTIDA, COMPLEXED WITH 1S-CAMPHOR
Descriptor: CAMPHOR, CYTOCHROME P450CAM, POTASSIUM ION, ...
Authors:Schlichting, I, Jung, C, Schulze, H.
Deposit date:1997-05-16
Release date:1997-11-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of cytochrome P-450cam complexed with the (1S)-camphor enantiomer.
FEBS Lett., 415, 1997
2BEN
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BU of 2ben by Molmil
Crystal structure of the Serratia marcescens chitin-binding protein CBP21 Y54A mutant.
Descriptor: CBP21
Authors:Vaaje-Kolstad, G, Houston, D.R, Eijsink, V.G.H, van Aalten, D.M.F.
Deposit date:2004-11-26
Release date:2004-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure and Binding Properties of the Serratia Marcescens Chitin-Binding Protein Cbp21
J.Biol.Chem., 280, 2005
1A7D
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BU of 1a7d by Molmil
CHLOROMET MYOHEMERYTHRIN FROM THEMISTE ZOSTERICOLA
Descriptor: CHLORIDE ION, CHLORO DIIRON-OXO MOIETY, MYOHEMERYTHRIN
Authors:Martins, L.J, Hill, C.P, Ellis Junior, W.R.
Deposit date:1998-03-12
Release date:1998-10-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of wild-type chloromet and L103N hydroxomet Themiste zostericola myohemerythrins at 1.8 A resolution.
Biochemistry, 36, 1997
2BZW
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BU of 2bzw by Molmil
The crystal structure of BCL-XL in complex with full-length BAD
Descriptor: APOPTOSIS REGULATOR BCL-X, BCL2-ANTAGONIST OF CELL DEATH
Authors:Lee, K.-H, Han, W.-D, Kim, K.-J, Oh, B.-H.
Deposit date:2005-08-24
Release date:2007-02-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral Bcl-2 of Murine Gamma-Herpesvirus 68.
Plos Pathog., 4, 2008
2BG1
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Active site restructuring regulates ligand recognition in classA Penicillin-binding proteins (PBPs)
Descriptor: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1B, SULFATE ION
Authors:Macheboeuf, P, Di Guilmi, A.M, Job, V, Vernet, T, Dideberg, O, Dessen, A.
Deposit date:2004-12-16
Release date:2005-03-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Active Site Restructuring Regulates Ligand Recognition in Class a Penicillin-Binding Proteins
Proc.Natl.Acad.Sci.USA, 102, 2005
2BLI
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L29W Mb deoxy
Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Nienhaus, K, Ostermann, A, Nienhaus, G.U, Parak, F.G, Schmidt, M.
Deposit date:2005-03-04
Release date:2005-04-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Ligand Migration and Protein Fluctuations in Myoglobin Mutant L29W
Biochemistry, 44, 2005
1A0L
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HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE
Descriptor: (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid, BETA-TRYPTASE
Authors:Pereira, P.J.B, Bergner, A, Macedo-Ribeiro, S, Huber, R, Matschiner, G, Fritz, H, Sommerhoff, C.P, Bode, W.
Deposit date:1997-12-03
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.
Nature, 392, 1998
1ADS
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BU of 1ads by Molmil
AN UNLIKELY SUGAR SUBSTRATE SITE IN THE 1.65 ANGSTROMS STRUCTURE OF THE HUMAN ALDOSE REDUCTASE HOLOENZYME IMPLICATED IN DIABETIC COMPLICATIONS
Descriptor: ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wilson, D.K, Quiocho, F.A.
Deposit date:1992-07-08
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications.
Science, 257, 1992
2C56
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A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1
Descriptor: URACIL DNA GLYCOSYLASE, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
Authors:Krusong, K, Carpenter, E.P, Bellamy, S.R.W, Savva, R, Baldwin, G.S.
Deposit date:2005-10-26
Release date:2005-11-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1.
J.Biol.Chem., 281, 2006

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