5ANV
 
 | | MTH1 in complex with compound 15 | | Descriptor: | 4-(4-CHLORO-2-FLUORO-ANILINO)-6,7-DIMETHOXY-N-METHYL-QUINOLINE-3-CARBOXAMIDE, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE | | Authors: | Read, J.A, Breed, J. | | Deposit date: | 2015-09-08 | | Release date: | 2016-03-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.16 Å) | | Cite: | Potent and Selective Inhibitors of Mth1 Probe its Role in Cancer Cell Survival.
J.Med.Chem., 59, 2016
|
|
6UXF
 | | Structure of V. metoecus NucC, hexamer form | | Descriptor: | Vibrio meotecus sp. RC341 NucC | | Authors: | Ye, Q, Corbett, K.D. | | Deposit date: | 2019-11-07 | | Release date: | 2019-12-25 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Mol.Cell, 77, 2020
|
|
6XQJ
 | | Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A | | Descriptor: | Protein Vpr,UV excision repair protein RAD23 homolog A, ZINC ION | | Authors: | Byeon, I.-J.L, Calero, G, Wu, Y, Byeon, C.H, Gronenborn, A.M. | | Deposit date: | 2020-07-09 | | Release date: | 2021-11-17 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A.
Nat Commun, 12, 2021
|
|
6B1T
 | | Improved cryoEM structure of human adenovirus type 5 with atomic details of minor proteins VI and VII | | Descriptor: | Hexon protein, Hexon-interlacing protein, Penton protein, ... | | Authors: | Dai, X.H, Wu, L, Sun, R, Zhou, Z.H. | | Deposit date: | 2017-09-18 | | Release date: | 2017-09-27 | | Last modified: | 2019-11-27 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Atomic Structures of Minor Proteins VI and VII in Human Adenovirus.
J. Virol., 91, 2017
|
|
6UXG
 | | Structure of V. metoecus NucC, trimer form | | Descriptor: | SULFATE ION, Vibrio metoecus sp. RC341 NucC | | Authors: | Ye, Q, Corbett, K.D. | | Deposit date: | 2019-11-07 | | Release date: | 2019-12-25 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Mol.Cell, 77, 2020
|
|
6YES
 | |
7B2X
 | | Crystal structure of human 5' exonuclease Appollo H61Y variant | | Descriptor: | 5' exonuclease Apollo, NICKEL (II) ION | | Authors: | Newman, J.A, Baddock, H.T, Mukhopadhyay, S.M.M, Burgess-Brown, N.A, von Delft, F, Arrowshmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | Deposit date: | 2020-11-28 | | Release date: | 2021-01-20 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.
Nucleic Acids Res., 49, 2021
|
|
1IRY
 | | Solution structure of the hMTH1, a nucleotide pool sanitization enzyme | | Descriptor: | hMTH1 | | Authors: | Mishima, M, Itoh, N, Sakai, Y, Kamiya, H, Nakabeppu, Y, Shirakawa, M. | | Deposit date: | 2001-10-25 | | Release date: | 2003-12-23 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates
J.Biol.Chem., 279, 2004
|
|
6Y24
 | | Crystal structure of fourth KH domain of FUBP1 | | Descriptor: | 1,2-ETHANEDIOL, Far upstream element-binding protein 1 | | Authors: | Ni, X, Joerger, A.C, Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2020-02-14 | | Release date: | 2020-03-25 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Comparative structural analyses and nucleotide-binding characterization of the four KH domains of FUBP1.
Sci Rep, 10, 2020
|
|
3VHS
 | |
5C9N
 | | Crystal structure of GEMC1 coiled-coil domain | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Geminin coiled-coil domain-containing protein 1 | | Authors: | Caillat, C, Perrakis, A. | | Deposit date: | 2015-06-28 | | Release date: | 2015-11-11 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins.
Acta Crystallogr.,Sect.D, 71, 2015
|
|
5C6G
 | |
6HQU
 | | Humanised RadA mutant HumRadA22 in complex with a recombined BRC repeat 8-2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Breast cancer type 2 susceptibility, DNA repair and recombination protein RadA, ... | | Authors: | Pantelejevs, T, Lindenburg, L, Hyvonen, M, Hollfelder, F. | | Deposit date: | 2018-09-25 | | Release date: | 2019-10-09 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
2J04
 | | The tau60-tau91 subcomplex of yeast transcription factor IIIC | | Descriptor: | HYPOTHETICAL PROTEIN YPL007C, YDR362CP | | Authors: | Mylona, A, Fernandez-Tornero, C, Legrand, P, Muller, C.W. | | Deposit date: | 2006-07-31 | | Release date: | 2006-10-23 | | Last modified: | 2019-04-03 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of the Tau60/Deltatau91 Subcomplex of Yeast Transcription Factor Iiic: Insights Into Preinitiation Complex Assembly
Mol.Cell, 24, 2006
|
|
7AKR
 | |
7AKS
 | |
7ARW
 | | Structure of human ARH3 E41A bound to alpha-NAD+ and magnesium | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ADP-ribose glycohydrolase ARH3, ... | | Authors: | Rack, J.G.M, Zorzini, V, Ahel, I. | | Deposit date: | 2020-10-26 | | Release date: | 2021-06-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal.
Nat Commun, 12, 2021
|
|
1PD7
 | | Extended SID of Mad1 bound to the PAH2 domain of mSin3B | | Descriptor: | Mad1, Sin3b protein | | Authors: | Van Ingen, H, Lasonder, E, Jansen, J.F, Kaan, A.M, Spronk, C.A, Stunnenberg, H.G, Vuister, G.W. | | Deposit date: | 2003-05-19 | | Release date: | 2004-01-20 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Extension of the binding motif of the sin3 interacting domain of the mad family proteins(,).
Biochemistry, 43, 2004
|
|
7AZT
 | | X-ray crystallographic structure of (6-4)photolyase from Drosophila melanogaster at room temperature | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, RE11660p | | Authors: | Cellini, A, Wahlgren, W.Y, Henry, L, Westenhoff, S, Pandey, S. | | Deposit date: | 2020-11-17 | | Release date: | 2021-08-18 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | The three-dimensional structure of Drosophila melanogaster (6-4) photolyase at room temperature.
Acta Crystallogr D Struct Biol, 77, 2021
|
|
7AYV
 | | X-ray crystallographic structure of (6-4)photolyase from Drosophila melanogaster at cryogenic temperature | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, RE11660p, ... | | Authors: | Cellini, A, Wahlgren, W.Y, Henry, L, Westenhoff, S. | | Deposit date: | 2020-11-13 | | Release date: | 2021-08-18 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | The three-dimensional structure of Drosophila melanogaster (6-4) photolyase at room temperature.
Acta Crystallogr D Struct Biol, 77, 2021
|
|
6JIV
 | | SspE crystal structure | | Descriptor: | SspE protein | | Authors: | Bing, Y.Z, Yang, H.G. | | Deposit date: | 2019-02-23 | | Release date: | 2020-03-25 | | Last modified: | 2020-07-08 | | Method: | X-RAY DIFFRACTION (3.31 Å) | | Cite: | SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities.
Nat Microbiol, 5, 2020
|
|
7B9B
 | | Crystal structure of human 5' exonuclease Appollo APO form | | Descriptor: | 5' exonuclease Apollo, NICKEL (II) ION | | Authors: | Newman, J.A, Baddock, H.T, Mukhopadhyay, S.M.M, Burgess-Brown, N.A, von Delft, F, Arrowshmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | Deposit date: | 2020-12-14 | | Release date: | 2021-01-20 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.
Nucleic Acids Res., 49, 2021
|
|
6JUF
 | | SspB crystal structure | | Descriptor: | SspB protein | | Authors: | Liqiong, L, Yubing, Z. | | Deposit date: | 2019-04-13 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.587 Å) | | Cite: | SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities.
Nat Microbiol, 5, 2020
|
|
7BI0
 | | GA repetition with i-motif clip at 5'-end | | Descriptor: | (CH+)C(CH+)GAGA, C(CH+)CGAGA | | Authors: | Novotny, A, Novotny, J. | | Deposit date: | 2021-01-12 | | Release date: | 2021-11-10 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Revealing structural peculiarities of homopurine GA repetition stuck by i-motif clip.
Nucleic Acids Res., 49, 2021
|
|
7BL0
 | | GA attached to an i-motif clip at 3'-end | | Descriptor: | GA(CH+)C(5MeCH+), GAC(HCY)(5MeC) | | Authors: | Novotny, A, Novotny, J. | | Deposit date: | 2021-01-17 | | Release date: | 2021-11-10 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Revealing structural peculiarities of homopurine GA repetition stuck by i-motif clip.
Nucleic Acids Res., 49, 2021
|
|
