7ARW

Structure of human ARH3 E41A bound to alpha-NAD+ and magnesium

Summary for 7ARW

• Entry DOI: 10.2210/pdb7arw/pdb
• Descriptor: ADP-ribose glycohydrolase ARH3, MAGNESIUM ION, alpha-Diphosphopyridine nucleotide, ... (6 entities in total)
• Functional Keywords: adp-ribose glycohydrolase, arh3, human, alpha-nad+, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 77879.50

Authors

Rack, J.G.M.,Zorzini, V.,Ahel, I. (deposition date: 2020-10-26, release date: 2021-06-16, Last modification date: 2024-01-31)

• Primary citation: Rack, J.G.M.,Liu, Q.,Zorzini, V.,Voorneveld, J.,Ariza, A.,Honarmand Ebrahimi, K.,Reber, J.M.,Krassnig, S.C.,Ahel, D.,van der Marel, G.A.,Mangerich, A.,McCullagh, J.S.O.,Filippov, D.V.,Ahel, I.; Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal.; Nat Commun, 12:4581-4581, 2021; PubMed: 34321462; DOI: 10.1038/s41467-021-24723-3

Experimental method

X-RAY DIFFRACTION (1.31 Å)