7ARW
Structure of human ARH3 E41A bound to alpha-NAD+ and magnesium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ADP-ribose glycohydrolase ARH3 | polymer | 349 | 37796.3 | 2 | UniProt (Q9NX46) Pfam (PF03747) | Homo sapiens (Human) | ADP-ribosylhydrolase 3,O-acetyl-ADP-ribose deacetylase ARH3,Poly(ADP-ribose) glycohydrolase ARH3,[Protein ADP-ribosylarginine] hydrolase-like protein 2,[Protein ADP-ribosylserine] hydrolase |
| 2 | C, D, M, N (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | E, O (A, B) | alpha-Diphosphopyridine nucleotide | non-polymer | 663.4 | 2 | Chemie (8NA) | |||
| 4 | F, G, H, J, K... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
| 5 | I, S (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 6 | W, X (A, B) | water | water | 18.0 | 755 | Chemie (HOH) |
Sequence modifications
A, B: 19 - 363 (UniProt: Q9NX46)
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Ser 18 | - | expression tag |
| Ala 41 | Glu 41 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75592.5 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2287.0 | |
| All* | Total formula weight | 77879.5 |
