7V08
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![BU of 7v08 by Molmil](/molmil-images/mine/7v08) | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a Spb1 D52A suppressor 3 strain | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | Authors: | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | Deposit date: | 2022-05-10 | Release date: | 2023-03-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.36 Å) | Cite: | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
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7YCX
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![BU of 7ycx by Molmil](/molmil-images/mine/7ycx) | The structure of INTAC-PEC complex | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. | Deposit date: | 2022-07-02 | Release date: | 2023-03-15 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Structural basis of INTAC-regulated transcription. Protein Cell, 14, 2023
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8HK1
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![BU of 8hk1 by Molmil](/molmil-images/mine/8hk1) | The cryo-EM structure of human pre-17S U2 snRNP | Descriptor: | ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... | Authors: | Zhang, X, Zhan, X, Shi, Y. | Deposit date: | 2022-11-24 | Release date: | 2023-03-08 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly. Nat Commun, 14, 2023
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7Q33
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![BU of 7q33 by Molmil](/molmil-images/mine/7q33) | |
8GXB
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![BU of 8gxb by Molmil](/molmil-images/mine/8gxb) | |
8GXC
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![BU of 8gxc by Molmil](/molmil-images/mine/8gxc) | |
7ZIR
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![BU of 7zir by Molmil](/molmil-images/mine/7zir) | Cryo-EM structure of hnRNPDL amyloid fibrils | Descriptor: | Heterogeneous nuclear ribonucleoprotein D-like | Authors: | Garcia-Pardo, J, Chaves-Sanjuan, A, Bartolome-Nafria, A, Gil-Garcia, M, Visentin, C, Bolognesi, M, Ricagno, S, Ventura, S. | Deposit date: | 2022-04-08 | Release date: | 2022-12-28 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3. Nat Commun, 14, 2023
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7WEZ
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![BU of 7wez by Molmil](/molmil-images/mine/7wez) | |
7QDE
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![BU of 7qde by Molmil](/molmil-images/mine/7qde) | |
7U0H
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![BU of 7u0h by Molmil](/molmil-images/mine/7u0h) | State NE1 nucleolar 60S ribosome biogenesis intermediate - Overall model | Descriptor: | 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | Deposit date: | 2022-02-18 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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7ZHR
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![BU of 7zhr by Molmil](/molmil-images/mine/7zhr) | |
8ESQ
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![BU of 8esq by Molmil](/molmil-images/mine/8esq) | Ytm1 associated nascent 60S ribosome State 2 | Descriptor: | 25S rRNA (cytosine-C(5))-methyltransferase nop2, 60S ribosomal protein L13, 60S ribosomal protein L14, ... | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | Deposit date: | 2022-10-14 | Release date: | 2022-11-30 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
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8EUY
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![BU of 8euy by Molmil](/molmil-images/mine/8euy) | Ytm1 associated nascent 60S ribosome (-fkbp39) State 1A | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | Deposit date: | 2022-10-19 | Release date: | 2022-11-30 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
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8ETH
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![BU of 8eth by Molmil](/molmil-images/mine/8eth) | Ytm1 associated 60S nascent ribosome State 1B | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | Deposit date: | 2022-10-17 | Release date: | 2022-11-30 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
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8ESR
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![BU of 8esr by Molmil](/molmil-images/mine/8esr) | Ytm1 associated nascent 60S ribosome (-fkbp39) State 2 | Descriptor: | 25S rRNA (cytosine-C(5))-methyltransferase nop2, 60S ribosomal protein L13, 60S ribosomal protein L14, ... | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | Deposit date: | 2022-10-14 | Release date: | 2022-11-30 | Last modified: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
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8ETI
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![BU of 8eti by Molmil](/molmil-images/mine/8eti) | Fkbp39 associated 60S nascent ribosome State 1 | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | Deposit date: | 2022-10-17 | Release date: | 2022-11-30 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
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8EUP
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![BU of 8eup by Molmil](/molmil-images/mine/8eup) | Ytm1 associated 60S nascent ribosome State 1A | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | Deposit date: | 2022-10-19 | Release date: | 2022-11-30 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
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8ETG
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![BU of 8etg by Molmil](/molmil-images/mine/8etg) | Fkbp39 associated 60S nascent ribosome State 3 | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | Deposit date: | 2022-10-17 | Release date: | 2022-11-30 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
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8EV3
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![BU of 8ev3 by Molmil](/molmil-images/mine/8ev3) | Ytm1 associated 60S nascent ribosome (-Fkbp39) State 1B | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... | Authors: | Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. | Deposit date: | 2022-10-19 | Release date: | 2022-11-30 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
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7Q8A
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![BU of 7q8a by Molmil](/molmil-images/mine/7q8a) | Crystal structure of tandem domain RRM1-2 of FUBP-interacting repressor (FIR) bound to FUSE ssDNA fragment | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(P*GP*T)-3'), Poly(U)-binding-splicing factor PUF60, ... | Authors: | Ni, X, Joerger, A.C, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-11-10 | Release date: | 2022-11-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of tandem domain RRM1-2 of FIR bound to FUSE ssDNA fragment To Be Published
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7R7A
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![BU of 7r7a by Molmil](/molmil-images/mine/7r7a) | State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model | Descriptor: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | Deposit date: | 2021-06-24 | Release date: | 2022-11-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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7R6Q
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![BU of 7r6q by Molmil](/molmil-images/mine/7r6q) | State E2 nucleolar 60S ribosome biogenesis intermediate - Foot region model | Descriptor: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | Deposit date: | 2021-06-23 | Release date: | 2022-11-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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8B8S
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![BU of 8b8s by Molmil](/molmil-images/mine/8b8s) | Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3 | Descriptor: | Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 | Authors: | Kachariya, N, Sattler, M, Keil, P, Strasser, K. | Deposit date: | 2022-10-04 | Release date: | 2022-11-09 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA. Nucleic Acids Res., 51, 2023
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7NAC
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![BU of 7nac by Molmil](/molmil-images/mine/7nac) | State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model | Descriptor: | 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | Deposit date: | 2021-06-21 | Release date: | 2022-11-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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7Z3X
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![BU of 7z3x by Molmil](/molmil-images/mine/7z3x) | Crystal structure of FIR RRM1-2 Y115F mutant bound to FUSE ssDNA | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*T)-3'), DNA (5'-D(P*GP*TP*())-3'), ... | Authors: | Ni, X, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2022-03-02 | Release date: | 2022-11-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of FIR RRM1-2 Y115F mutant bound to FUSE ssDNA To Be Published
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