2A7R
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![BU of 2a7r by Molmil](/molmil-images/mine/2a7r) | Crystal structure of human Guanosine Monophosphate reductase 2 (GMPR2) | Descriptor: | GMP reductase 2, GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION | Authors: | Li, J, Wei, Z, Zheng, M, Gu, X, Deng, Y, Qiu, R, Chen, F, Ji, C, Gong, W, Xie, Y, Mao, Y. | Deposit date: | 2005-07-05 | Release date: | 2006-01-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of Human Guanosine Monophosphate Reductase 2 (GMPR2) in Complex with GMP J.Mol.Biol., 355, 2006
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1UXU
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![BU of 1uxu by Molmil](/molmil-images/mine/1uxu) | Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax | Descriptor: | ADENOSINE MONOPHOSPHATE, GLYCERALDEHYDE-3-PHOSPHATE, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+), ... | Authors: | Lorentzen, E, Hensel, R, Pohl, E. | Deposit date: | 2004-03-01 | Release date: | 2004-08-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol., 341, 2004
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5HVX
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![BU of 5hvx by Molmil](/molmil-images/mine/5hvx) | Full length Wild-Type Open-form Sodium Channel NavMs | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DODECAETHYLENE GLYCOL, ... | Authors: | Sula, A, Booker, J.E, Naylor, C.E, Wallace, B.A. | Deposit date: | 2016-01-28 | Release date: | 2017-03-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The complete structure of an activated open sodium channel. Nat Commun, 8, 2017
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6DJ7
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![BU of 6dj7 by Molmil](/molmil-images/mine/6dj7) | HIV-1 protease with mutation L76V in complex with GRL-5010 (gem-difluoro-bis-tetrahydrofuran as P2 ligand) | Descriptor: | (3R,3aS,6aS)-4,4-difluorohexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ... | Authors: | Wong-Sam, A.E, Wang, Y.F, Weber, I.T. | Deposit date: | 2018-05-24 | Release date: | 2018-10-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Drug Resistance Mutation L76V Alters Nonpolar Interactions at the Flap-Core Interface of HIV-1 Protease. ACS Omega, 3, 2018
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6DML
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![BU of 6dml by Molmil](/molmil-images/mine/6dml) | A multiconformer ligand model of 3,5 dimethylisoxaxole bound to the bromodomain of human BRD4 | Descriptor: | 1,2-ETHANEDIOL, 4-((2-(tert-butyl)phenyl)amino)-7-(3,5-dimethylisoxazol-4-yl)-6-methoxy-1,5-naphthyridine-3-carboxylic acid, Bromodomain-containing protein 4 | Authors: | Hudson, B.M, van Zundert, G, Keedy, D.A, Fonseca, R, Heliou, A, Suresh, P, Borrelli, K, Day, T, Fraser, J.S, van den Bedem, H. | Deposit date: | 2018-06-05 | Release date: | 2018-12-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | qFit-ligand Reveals Widespread Conformational Heterogeneity of Drug-Like Molecules in X-Ray Electron Density Maps. J. Med. Chem., 61, 2018
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6D9J
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![BU of 6d9j by Molmil](/molmil-images/mine/6d9j) | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1. | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Pisareva, V.P, Pisarev, A.V, Fernandez, I.S. | Deposit date: | 2018-04-30 | Release date: | 2018-06-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES. Elife, 7, 2018
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7CSJ
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![BU of 7csj by Molmil](/molmil-images/mine/7csj) | Aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis-Complex with Coenzyme A and Gentamicin | Descriptor: | Aminoglycoside 2'-N-acetyltransferase, COENZYME A, gentamicin C1 | Authors: | Jeong, C.S, Hwang, J, Do, H, Lee, J.H. | Deposit date: | 2020-08-14 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.168 Å) | Cite: | Structural and biochemical analyses of an aminoglycoside 2'-N-acetyltransferase from Mycolicibacterium smegmatis. Sci Rep, 10, 2020
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7CPZ
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![BU of 7cpz by Molmil](/molmil-images/mine/7cpz) | Crystal structure of Streptoavidin-C1 from Streptomyces cinamonensis | Descriptor: | BIOTIN, Mature Streptoavidin-C1 | Authors: | Jeon, B.J, Kim, S, Lee, J.-H, Kim, M.S, Hwang, K.Y. | Deposit date: | 2020-08-08 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insights into the structure of mature streptavidin C1 from Streptomyces cinnamonensis reveal the self-binding of the extension C-terminal peptide to biotin-binding sites. Iucrj, 8, 2021
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7CQ0
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![BU of 7cq0 by Molmil](/molmil-images/mine/7cq0) | Crystal structure of Streptoavidin-C1 from Streptomyces cinamonensis | Descriptor: | Mature Streptoavidin-C1 | Authors: | Jeon, B.J, Kim, S, Lee, J.-H, Kim, M.S, Hwang, K.Y. | Deposit date: | 2020-08-08 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Insights into the structure of mature streptavidin C1 from Streptomyces cinnamonensis reveal the self-binding of the extension C-terminal peptide to biotin-binding sites. Iucrj, 8, 2021
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4AXD
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![BU of 4axd by Molmil](/molmil-images/mine/4axd) | Inositol 1,3,4,5,6-pentakisphosphate 2-kinase in complex with AMPPNP | Descriptor: | CITRIC ACID, INOSITOL-PENTAKISPHOSPHATE 2-KINASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | I Banos-Sanz, J, Sanz-Aparicio, J, Gonzalez, B. | Deposit date: | 2012-06-12 | Release date: | 2012-07-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Conformational Changes Undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon Substrate Binding: The Role of N-Lobe and Enantiomeric Substrate Preference J.Biol.Chem., 287, 2012
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3T25
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![BU of 3t25 by Molmil](/molmil-images/mine/3t25) | TMAO-grown orthorhombic trypsin (bovine) | Descriptor: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | Authors: | Cahn, J, Venkat, M, Marshall, H, Juers, D. | Deposit date: | 2011-07-22 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
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6H0Q
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![BU of 6h0q by Molmil](/molmil-images/mine/6h0q) | B1-type ACP domain from module 7 of MLSB | Descriptor: | Type I modular polyketide synthase | Authors: | Moretto, L, Heylen, R, Holroyd, N, Vance, S, Broadhurst, R.W. | Deposit date: | 2018-07-10 | Release date: | 2019-03-06 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold. Sci Rep, 9, 2019
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4AXC
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![BU of 4axc by Molmil](/molmil-images/mine/4axc) | Inositol 1,3,4,5,6-pentakisphosphate 2-kinase apo form | Descriptor: | GLYCEROL, INOSITOL-PENTAKISPHOSPHATE 2-KINASE, SULFATE ION, ... | Authors: | I Banos-Sanz, J, Sanz-Aparicio, J, Gonzalez, B. | Deposit date: | 2012-06-12 | Release date: | 2012-07-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Conformational Changes Undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon Substrate Binding: The Role of N-Lobe and Enantiomeric Substrate Preference J.Biol.Chem., 287, 2012
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6H0J
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![BU of 6h0j by Molmil](/molmil-images/mine/6h0j) | A1-type ACP domain from module 5 of MLSA1 | Descriptor: | Type I modular polyketide synthase | Authors: | Moretto, L, Heylen, R, Holroyd, N, Vance, S, Broadhurst, R.W. | Deposit date: | 2018-07-09 | Release date: | 2019-03-06 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold. Sci Rep, 9, 2019
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4AXE
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![BU of 4axe by Molmil](/molmil-images/mine/4axe) | Inositol 1,3,4,5,6-pentakisphosphate 2-kinase in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, INOSITOL-PENTAKISPHOSPHATE 2-KINASE, SULFATE ION, ... | Authors: | I Banos-Sanz, J, Sanz-Aparicio, J, Gonzalez, B. | Deposit date: | 2012-06-12 | Release date: | 2012-07-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Conformational Changes Undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon Substrate Binding: The Role of N-Lobe and Enantiomeric Substrate Preference J.Biol.Chem., 287, 2012
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6JHX
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![BU of 6jhx by Molmil](/molmil-images/mine/6jhx) | |
3I29
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![BU of 3i29 by Molmil](/molmil-images/mine/3i29) | Crystal structure of a binary complex between an mutant trypsin inhibitor with bovine trypsin | Descriptor: | CALCIUM ION, Cationic trypsin, Chymotrypsin inhibitor 3 | Authors: | Khamrui, S, Majumder, S, Dasgupta, J, Dattagupta, J.K, Sen, U. | Deposit date: | 2009-06-29 | Release date: | 2010-06-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors Biochim.Biophys.Acta, 1824, 2012
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6JPH
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![BU of 6jph by Molmil](/molmil-images/mine/6jph) | Crystal structure of the catalytic domain of a multi-domain alginate lyase Dp0100 from thermophilic bacterium Defluviitalea phaphyphila | Descriptor: | ACETATE ION, Alginate lyase, CALCIUM ION, ... | Authors: | Ji, S.Q, Dix, S.R, Aziz, A, Sedelnikova, S.E, Li, F.L, Rice, D.W. | Deposit date: | 2019-03-27 | Release date: | 2019-10-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.759 Å) | Cite: | The molecular basis of endolytic activity of a multidomain alginate lyase fromDefluviitalea phaphyphila, a representative of a new lyase family, PL39. J.Biol.Chem., 294, 2019
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6JPN
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![BU of 6jpn by Molmil](/molmil-images/mine/6jpn) | Crystal structure of the catalytic domain of a multi-domain alginate lyase Dp0100 from thermophilic bacterium Defluviitalea phaphyphila | Descriptor: | Alginate lyase, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Ji, S.Q, Dix, S.R, Aziz, A, Sedelnikova, S.E, Li, F.L, Rice, D.W. | Deposit date: | 2019-03-27 | Release date: | 2019-10-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | The molecular basis of endolytic activity of a multidomain alginate lyase fromDefluviitalea phaphyphila, a representative of a new lyase family, PL39. J.Biol.Chem., 294, 2019
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1XYC
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![BU of 1xyc by Molmil](/molmil-images/mine/1xyc) | X-RAY CRYSTALLOGRAPHIC STRUCTURES OF D-XYLOSE ISOMERASE-SUBSTRATE COMPLEXES POSITION THE SUBSTRATE AND PROVIDE EVIDENCE FOR METAL MOVEMENT DURING CATALYSIS | Descriptor: | 3-O-METHYLFRUCTOSE IN LINEAR FORM, MAGNESIUM ION, XYLOSE ISOMERASE | Authors: | Lavie, A, Allen, K.N, Petsko, G.A, Ringe, D. | Deposit date: | 1994-01-03 | Release date: | 1994-05-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | X-ray crystallographic structures of D-xylose isomerase-substrate complexes position the substrate and provide evidence for metal movement during catalysis. Biochemistry, 33, 1994
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1XYB
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![BU of 1xyb by Molmil](/molmil-images/mine/1xyb) | X-RAY CRYSTALLOGRAPHIC STRUCTURES OF D-XYLOSE ISOMERASE-SUBSTRATE COMPLEXES POSITION THE SUBSTRATE AND PROVIDE EVIDENCE FOR METAL MOVEMENT DURING CATALYSIS | Descriptor: | D-glucose, MAGNESIUM ION, XYLOSE ISOMERASE | Authors: | Lavie, A, Allen, K.N, Petsko, G.A, Ringe, D. | Deposit date: | 1994-01-03 | Release date: | 1994-05-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | X-ray crystallographic structures of D-xylose isomerase-substrate complexes position the substrate and provide evidence for metal movement during catalysis. Biochemistry, 33, 1994
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6DAO
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![BU of 6dao by Molmil](/molmil-images/mine/6dao) | NahE WT selenomethionine | Descriptor: | Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase | Authors: | Medellin, B.P, LeVieux, J.A, Zhang, Y.J, Whitman, C.P. | Deposit date: | 2018-05-01 | Release date: | 2019-05-08 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.939 Å) | Cite: | Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily. Biochemistry, 57, 2018
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1XIS
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![BU of 1xis by Molmil](/molmil-images/mine/1xis) | |
7D6B
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![BU of 7d6b by Molmil](/molmil-images/mine/7d6b) | Crystal structure of Oryza sativa Os4BGlu18 monolignol beta-glucosidase with delta-gluconolactone | Descriptor: | Beta-glucosidase 18, D-glucono-1,5-lactone, GLYCEROL, ... | Authors: | Baiya, S, Pengthaisong, S, Ketudat Cairns, J.R. | Deposit date: | 2020-09-29 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural analysis of rice Os4BGlu18 monolignol beta-glucosidase. Plos One, 16, 2021
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3T27
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![BU of 3t27 by Molmil](/molmil-images/mine/3t27) | Orthorhombic trypsin (bovine) in the presence of betaine | Descriptor: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | Authors: | Venkat, M, Saxby, C, Cahn, J, Juers, D. | Deposit date: | 2011-07-22 | Release date: | 2011-12-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
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