3II4
 
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1D0E
 | | CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN | | Descriptor: | 5'-D(*TP*TP*TP*CP*AP*TP*GP*CP*AP*TP*G)-3', REVERSE TRANSCRIPTASE | | Authors: | Najmudin, S, Cote, M.L, Sun, D, Yohannan, S, Montano, S.P, Gu, J, Georgiadis, M.M. | | Deposit date: | 1999-09-09 | | Release date: | 2000-04-04 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain
J.Mol.Biol., 296, 2000
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2WMZ
 | | Structure of a mutated TolC | | Descriptor: | CHLORIDE ION, OUTER MEMBRANE PROTEIN TOLC, SODIUM ION, ... | | Authors: | Hinchliffe, P, Pei, X.Y, Symmons, M.F, Koronakis, E, Hughes, C, Koronakis, V. | | Deposit date: | 2009-07-03 | | Release date: | 2011-01-26 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structures of Sequential Open States in a Symmetrical Opening Transition of the Tolc Exit Duct.
Proc.Natl.Acad.Sci.USA, 108, 2011
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7QI1
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2NOL
 | | Structure of catalytically inactive human 8-oxoguanine glycosylase distal crosslink to oxoG DNA | | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | | Authors: | Banerjee, A, Radom, C.T, Verdine, G.L. | | Deposit date: | 2006-10-25 | | Release date: | 2006-11-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
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6EB0
 | | STRUCTURE OF 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE (HPAB), OXYGENASE COMPONENT FROM ESCHERICHIA COLI | | Descriptor: | 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit, ACETATE ION | | Authors: | Zhou, D, Kandavelu, P, Zhang, H, Wang, B.C, Yan, Y, Rose, J. | | Deposit date: | 2018-08-03 | | Release date: | 2019-05-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Structural Insights into Catalytic Versatility of the Flavin-dependent Hydroxylase (HpaB) from Escherichia coli.
Sci Rep, 9, 2019
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2NNJ
 | | CYP2C8dH complexed with felodipine | | Descriptor: | Cytochrome P450 2C8, FELODIPINE, PALMITIC ACID, ... | | Authors: | Schoch, G.A, Yano, J.K, Stout, C.D, Johnson, E.F. | | Deposit date: | 2006-10-24 | | Release date: | 2007-10-23 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid.
J.Biol.Chem., 283, 2008
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5X23
 | | Crystal structure of CYP2C9 genetic variant A477T (*30) in complex with multiple losartan molecules | | Descriptor: | Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ... | | Authors: | Maekawa, K, Adachi, M, Shah, M.B. | | Deposit date: | 2017-01-30 | | Release date: | 2017-10-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9
Biochemistry, 56, 2017
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2NOH
 | | Structure of catalytically inactive Q315A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA | | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | | Deposit date: | 2006-10-25 | | Release date: | 2006-11-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
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7QDO
 | | Cryo-EM structure of human monomeric IgM-Fc | | Descriptor: | Isoform 2 of Immunoglobulin heavy constant mu | | Authors: | Chen, Q, Rosenthal, P, Tolar, P. | | Deposit date: | 2021-11-27 | | Release date: | 2022-10-26 | | Last modified: | 2022-11-09 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
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2NOZ
 | | Structure of Q315F human 8-oxoguanine glycosylase distal crosslink to 8-oxoguanine DNA | | Descriptor: | 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*G*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | | Deposit date: | 2006-10-26 | | Release date: | 2006-11-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
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5WXY
 | | Crystal structure of Microcystis aeruginosa PCC 7806 aspartate racemase in complex with L-aspartate | | Descriptor: | ASPARTIC ACID, McyF | | Authors: | Cao, D.D, Zhou, K, Jiang, Y.L, Zhou, C.Z. | | Deposit date: | 2017-01-09 | | Release date: | 2018-01-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Structural insights into the catalysis and substrate specificity of cyanobacterial aspartate racemase McyF.
Biochem.Biophys.Res.Commun., 514, 2019
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1CT5
 | | CRYSTAL STRUCTURE OF YEAST HYPOTHETICAL PROTEIN YBL036C-SELENOMET CRYSTAL | | Descriptor: | PROTEIN (YEAST HYPOTHETICAL PROTEIN, SELENOMET), PYRIDOXAL-5'-PHOSPHATE | | Authors: | Eswaramoorthy, S, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 1999-08-18 | | Release date: | 1999-09-02 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of a yeast hypothetical protein selected by a structural genomics approach.
Acta Crystallogr.,Sect.D, 59, 2003
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1CGE
 | | CRYSTAL STRUCTURES OF RECOMBINANT 19-KDA HUMAN FIBROBLAST COLLAGENASE COMPLEXED TO ITSELF | | Descriptor: | CALCIUM ION, FIBROBLAST COLLAGENASE, ZINC ION | | Authors: | Lovejoy, B, Hassell, A.M, Luther, M.A, Weigl, D, Jordan, S.R. | | Deposit date: | 1994-02-03 | | Release date: | 1995-03-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structures of recombinant 19-kDa human fibroblast collagenase complexed to itself.
Biochemistry, 33, 1994
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2NOF
 | | Structure of Q315F human 8-oxoguanine glycosylase proximal crosslink to 8-oxoguanine DNA | | Descriptor: | 5'-D(*GP*CP*GP*TP*C*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | | Deposit date: | 2006-10-25 | | Release date: | 2006-11-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
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2IJ5
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2NOI
 | | Structure of G42A human 8-oxoguanine glycosylase crosslinked to undamaged G-containing DNA | | Descriptor: | 5'-D(*GP*CP*GP*TP*C*CP*AP*GP*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | | Deposit date: | 2006-10-25 | | Release date: | 2006-11-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
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1D75
 | | CONFORMATION OF THE GUANINE.8-OXOADENINE BASE PAIRS IN THE CRYSTAL STRUCTURE OF D(CGCGAATT(O8A)GCG) | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(A38)P*GP*CP*G)-3') | | Authors: | Leonard, G.A, Guy, A, Brown, T, Teoule, R, Hunter, W.N. | | Deposit date: | 1992-05-07 | | Release date: | 1993-01-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Conformation of guanine-8-oxoadenine base pairs in the crystal structure of d(CGCGAATT(O8A)GCG).
Biochemistry, 31, 1992
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2NOB
 | | Structure of catalytically inactive H270A human 8-oxoguanine glycosylase crosslinked to 8-oxoguanine DNA | | Descriptor: | 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*T*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | | Deposit date: | 2006-10-25 | | Release date: | 2006-11-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
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2NOE
 | | Structure of catalytically inactive G42A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA | | Descriptor: | 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*G*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | | Deposit date: | 2006-10-25 | | Release date: | 2006-11-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
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3KEG
 | | X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED | | Descriptor: | 2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC ACID, FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase 1, ... | | Authors: | Wang, C.-J, Laurieri, N, Abuhammad, A, Lowe, E, Westwood, I, Ryan, A, Sim, E. | | Deposit date: | 2009-10-26 | | Release date: | 2010-01-12 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide
Acta Crystallogr.,Sect.F, 66, 2010
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1CZM
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1CJL
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2J5L
 | | Structure of a Plasmodium falciparum apical membrane antigen 1-Fab F8. 12.19 complex | | Descriptor: | APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19 | | Authors: | Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A. | | Deposit date: | 2006-09-18 | | Release date: | 2007-01-30 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation.
J.Mol.Biol., 366, 2007
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5WBG
 | | Crystal Structure of human Cytochrome P450 2B6 (Y226H/K262R) in complex with an analog of a drug Efavirenz | | Descriptor: | (2R,4S)-6-chloro-4-(cyclopropylethynyl)-2-methyl-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, 5-cyclohexylpentan-1-ol, ... | | Authors: | Shah, M.B, Halpert, J.R. | | Deposit date: | 2017-06-29 | | Release date: | 2018-05-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Crystal Structure of CYP2B6 in Complex with an Efavirenz Analog.
Int J Mol Sci, 19, 2018
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