PDB: 265 resultsInfo pagesStatus searchChemie searchBIRD

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4DSJ	Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with duplex DNA, dGTP and Calcium Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA, ... Authors: Gan, J.H, Abdur, R, Liu, H.H, Sheng, J, Caton-Willians, J, Soares, A.S, Huang, Z. Deposit date: 2012-02-19 Release date: 2013-03-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.86 Å) Cite: Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase To be Published
4DSK	Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with duplex DNA, PPi and Calcium Descriptor: CALCIUM ION, DNA (5'-D(*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*CP*G)-3'), DNA (5'-D(*TP*CP*AP*CP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3'), ... Authors: Gan, J.H, Abdur, R, Liu, H.H, Sheng, J, Caton-Willians, J, Soares, A.S, Huang, Z. Deposit date: 2012-02-19 Release date: 2013-03-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase To be Published
4DSL	Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with duplex DNA and Calcium Descriptor: DNA (5'-D(*G*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*C)-3'), DNA (5'-D(*TP*CP*AP*CP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3'), DNA polymerase, ... Authors: Gan, J.H, Abdur, R, Liu, H.H, Sheng, J, Caton-Willians, J, Soares, A.S, Huang, Z. Deposit date: 2012-02-19 Release date: 2013-03-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase To be Published
4DWI	Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with self complementary DNA, Se-dGTP and Calcium Descriptor: 9-METHYLGUANINE, CALCIUM ION, DNA (5'-D(*AP*CP*TP*GP*GP*AP*TP*CP*CP*A)-3'), ... Authors: Gan, J.H, Abdur, R, Liu, H.H, Sheng, J, Caton-Willians, J, Soares, A.S, Huang, Z. Deposit date: 2012-02-24 Release date: 2013-03-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase To be Published
4E0D	Binary complex of Bacillus DNA Polymerase I Large Fragment E658A and duplex DNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... Authors: Wang, W, Beese, L.S. Deposit date: 2012-03-02 Release date: 2012-06-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. J.Biol.Chem., 287, 2012
4ELT	Snapshot of the large fragment of DNA polymerase I from Thermus Aquaticus processing modified pyrimidines Descriptor: 1,2-ETHANEDIOL, 2'-deoxy-5-[(4-ethynylphenyl)ethynyl]uridine 5'-(tetrahydrogen triphosphate), ACETATE ION, ... Authors: Marx, A, Diederichs, K, Obeid, S. Deposit date: 2012-04-11 Release date: 2013-03-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Interactions of non-polar and "Click-able" nucleotides in the confines of a DNA polymerase active site. Chem.Commun.(Camb.), 48, 2012
4ELU	Snapshot of the large fragment of DNA polymerase I from Thermus Aquaticus processing modified pyrimidines Descriptor: 2'-deoxy-5-[(4-ethynylphenyl)ethynyl]cytidine 5'-(tetrahydrogen triphosphate), ACETATE ION, DNA (5'-D(*AP*AP*AP*GP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... Authors: Marx, A, Diederichs, K, Obeid, S. Deposit date: 2012-04-11 Release date: 2013-03-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Interactions of non-polar and "Click-able" nucleotides in the confines of a DNA polymerase active site. Chem.Commun.(Camb.), 48, 2012
4ELV	Snapshot of the large fragment of DNA polymerase I from Thermus Aquaticus processing modified pyrimidines Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*AP*AP*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... Authors: Marx, A, Diederichs, K, Obeid, S. Deposit date: 2012-04-11 Release date: 2013-04-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Snapshot of the large fragment of DNA polymerase I from Thermus Aquaticus processing modified pyrimidines To be Published
4EZ6	Bacillus DNA Polymerase I Large Fragment Complex 1 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... Authors: Wang, W, Beese, L.S. Deposit date: 2012-05-02 Release date: 2013-07-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Structures of a High-fidelity DNA Polymerase to be published
4EZ9	Bacillus DNA Polymerase I Large Fragment Complex 2 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... Authors: Wang, W, Beese, L.S. Deposit date: 2012-05-02 Release date: 2013-07-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Structures of a High-fidelity DNA Polymerase to be published
4F2R	DNA Polymerase I Large Fragment complex 3 Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... Authors: Wang, W, Beese, L.S. Deposit date: 2012-05-08 Release date: 2013-07-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Structures of a High-fidelity DNA Polymerase to be published
4F2S	DNA Polymerase I Large Fragment complex 4 Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... Authors: Wang, W, Beese, L.S. Deposit date: 2012-05-08 Release date: 2013-07-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.651 Å) Cite: Structures of a High-fidelity DNA Polymerase to be published
4F3O	DNA Polymerase I Large Fragment Complex 5 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*C*AP*TP*GP*AP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... Authors: Wang, W, Beese, L.S. Deposit date: 2012-05-09 Release date: 2013-07-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Structures of a High-fidelity DNA Polymerase to be published
4F4K	DNA Polymerase I Large Fragment Complex 6 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... Authors: Wang, W, Beese, L.S. Deposit date: 2012-05-10 Release date: 2013-07-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structures of a High-fidelity DNA Polymerase to be published
4F8R	Bacillus DNA Polymerase I Large Fragment complex 7 Descriptor: DNA (5'-D(*CP*AP*TP*TP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3'), DNA polymerase, ... Authors: Wang, W, Beese, L.S. Deposit date: 2012-05-17 Release date: 2013-08-07 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Structures of a High-fidelity DNA Polymerase to be published
4KTQ	BINARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM T. AQUATICUS BOUND TO A PRIMER/TEMPLATE DNA Descriptor: DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), PROTEIN (LARGE FRAGMENT OF DNA POLYMERASE I) Authors: Li, Y, Waksman, G. Deposit date: 1998-09-09 Release date: 1999-01-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation. EMBO J., 17, 1998
4N56	Binary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant (Cs3C KlenTaq) with DNA Descriptor: 5'-D(*AP*AP*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3', DNA polymerase I, ... Authors: Wu, E.Y. Deposit date: 2013-10-09 Release date: 2015-01-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase. Biochemistry, 54, 2015
4N5S	Ternary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant (Cs3C KlenTaq) with DNA and ddCTP Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-D(*AP*A*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', ... Authors: Wu, E.Y. Deposit date: 2013-10-10 Release date: 2015-01-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.67 Å) Cite: A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase. Biochemistry, 54, 2015
4O0I	Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with 2'-MeSe-arabino-guanosine derivatized DNA Descriptor: 5'-D(*C*(1TW)P*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', DNA polymerase I, GLYCEROL, ... Authors: Jiang, S, Gan, J, Sun, H, Huang, Z. Deposit date: 2013-12-13 Release date: 2014-12-17 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.203 Å) Cite: Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with 2'-MeSe-arabino-guanosine derivatized DNA TO BE PUBLISHED
4UQG	A new bio-isosteric base pair based on reversible bonding Descriptor: 5'-D(*AP*GP*GP*GP*A SAYP*GP*GP*TP*CP)-3', 5'-D(*GP*AP*CP*C T0TP*TP*CP*CP*CP*TP)-3', DNA POLYMERASE, ... Authors: Tomas-Gamasa, M, Serdjukov, S, Su, M, Mueller, M, Carell, T. Deposit date: 2014-06-23 Release date: 2014-12-03 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2 Å) Cite: "Post-it" type connected DNA created with a reversible covalent cross-link. Angew. Chem. Int. Ed. Engl., 54, 2015
4X0P	Ternary complex of human DNA polymerase theta C-terminal domain binding ddATP opposite a tetrahydrofuran AP site analog Descriptor: 2',3'-dideoxyadenosine triphosphate, CALCIUM ION, DNA (5'-D(*CP*GP*TP*TP*GP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), ... Authors: Zahn, K.E, Doublie, S. Deposit date: 2014-11-21 Release date: 2015-03-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.911 Å) Cite: Human DNA polymerase theta grasps the primer terminus to mediate DNA repair. Nat.Struct.Mol.Biol., 22, 2015
4X0Q	Ternary complex of human DNA polymerase theta C-terminal domain binding ddGTP opposite dCMP Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*CP*CP*AP*AP*TP*GP*AP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*TP*CP*AP*TP*TP*G)-3'), ... Authors: Zahn, K.E, Doublie, S. Deposit date: 2014-11-22 Release date: 2015-03-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Human DNA polymerase theta grasps the primer terminus to mediate DNA repair. Nat.Struct.Mol.Biol., 22, 2015
4XIU	Binary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant with DNA containing TTT overhang Descriptor: DNA polymerase I, thermostable, MAGNESIUM ION, ... Authors: Wu, E.Y. Deposit date: 2015-01-07 Release date: 2015-01-21 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase. Biochemistry, 54, 2015
4XVI	Binary complex of human polymerase nu and DNA with the finger domain ajar Descriptor: DNA (5'-D(*AP*CP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*CP*AP*G)-3'), DNA polymerase nu Authors: Lee, Y.-S, Yang, W. Deposit date: 2015-01-27 Release date: 2015-03-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.1 Å) Cite: How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015
4XVK	Binary complex of human polymerase nu and DNA with the finger domain closed Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ... Authors: Lee, Y.-S, Yang, W. Deposit date: 2015-01-27 Release date: 2015-03-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.95 Å) Cite: How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. Nat.Struct.Mol.Biol., 22, 2015

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