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7PNE
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Parallel Q-D hybrid with 3' duplex stem-loop as a lateral snapback loop
Descriptor: TTAMycdup-3sbl
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2021-09-06
Release date:2021-12-29
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces.
Chemistry, 28, 2022
7PNG
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BU of 7png by Molmil
Solution structure of 1:1 complex of an indoloquinoline derivative SYUIQ-5 to parallel quadruplex-duplex (Q-D) hybrid
Descriptor: DNA (37-MER), ~{N}-(5~{H}-indolo[3,2-b]quinolin-11-yl)-~{N}',~{N}'-dimethyl-propane-1,3-diamine
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2021-09-06
Release date:2021-12-29
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces.
Chemistry, 28, 2022
2OZ4
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BU of 2oz4 by Molmil
Structural Plasticity in IgSF Domain 4 of ICAM-1 Mediates Cell Surface Dimerization
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB FRAGMENT LIGHT CHAIN, ...
Authors:Chen, X, Kim, T.D, Carman, C.V, Mi, L, Song, G, Springer, T.A.
Deposit date:2007-02-23
Release date:2007-10-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerization.
Proc.Natl.Acad.Sci.Usa, 104, 2007
8W8T
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BU of 8w8t by Molmil
Crystal structure of human CLEC12A CRD
Descriptor: C-type lectin domain family 12 member A, SULFATE ION
Authors:Mori, S, Nagae, M, Yamasaki, S.
Deposit date:2023-09-04
Release date:2024-03-06
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.
Int.Immunol., 36, 2024
2PFI
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BU of 2pfi by Molmil
Crystal structure of the cytoplasmic domain of the human chloride channel ClC-Ka
Descriptor: CHLORIDE ION, Chloride channel protein ClC-Ka, IODIDE ION
Authors:Markovic, S, Dutzler, R.
Deposit date:2007-04-05
Release date:2007-06-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Structure of the Cytoplasmic Domain of the Chloride Channel ClC-Ka Reveals a Conserved Interaction Interface.
Structure, 15, 2007
2Q81
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Crystal Structure of the Miz-1 BTB/POZ domain
Descriptor: Miz-1 protein, TETRAETHYLENE GLYCOL
Authors:Stead, M.A, Trinh, C.H, Garnett, J.A, Carr, S.B, Edwards, T.A, Wright, S.C.
Deposit date:2007-06-08
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Beta-Sheet Interaction Interface Directs the Tetramerisation of the Miz-1 POZ Domain
J.Mol.Biol., 373, 2007
4K71
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BU of 4k71 by Molmil
Crystal structure of a high affinity Human Serum Albumin variant bound to the Neonatal Fc Receptor
Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, SULFATE ION, ...
Authors:Schmidt, M.M, Townson, S.A, Andreucci, A, Dombrowski, C, Erbe, D.V, King, B, Kovalchin, J.T, Masci, A, Murillo, A, Schirmer, E.B, Furfine, E.S, Barnes, T.M.
Deposit date:2013-04-16
Release date:2013-10-23
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of an HSA/FcRn complex reveals recycling by competitive mimicry of HSA ligands at a pH-dependent hydrophobic interface.
Structure, 21, 2013
8W9H
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BU of 8w9h by Molmil
Crystal structure of anti-human CLEC12A antibody 50C1
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, anti-human CLEC12A antibody 50C1 Fab Heavy chain, ...
Authors:Mori, S, Nagae, M, Yamasaki, S.
Deposit date:2023-09-05
Release date:2024-03-06
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.
Int.Immunol., 36, 2024
8W9J
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BU of 8w9j by Molmil
Crystal structure of human CLEC12A ectodomain complexed with 50C1 Fab
Descriptor: Anti-human CLEC12A antibody 50C1 heavy chain, Anti-human CLEC12A antibody 50C1 light chain, C-type lectin domain family 12 member A
Authors:Mori, S, Nagae, M, Yamasaki, S.
Deposit date:2023-09-05
Release date:2024-03-06
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.
Int.Immunol., 36, 2024
4L56
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tRNA guanine transglycosylase H333D mutant apo structure
Descriptor: GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION
Authors:Nguyen, T.X.P, Heine, A, Klebe, G.
Deposit date:2013-06-10
Release date:2014-12-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:What Glues a Homodimer Together: Systematic Analysis of the Stabilizing Effect of an Aromatic Hot Spot in the Protein-Protein Interface of the tRNA-Modifying Enzyme Tgt.
Acs Chem.Biol., 10, 2015
4GOF
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Crystal structure of the SGTA homodimerization domain with covalent modifications to both C38
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Small glutamine-rich tetratricopeptide repeat-containing protein alpha
Authors:Chartron, J.W, VanderVelde, D.G, Clemons Jr, W.M.
Deposit date:2012-08-19
Release date:2012-11-21
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2, 2012
4GOE
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BU of 4goe by Molmil
Crystal structure of the SGTA homodimerization domain with a covalent modification of a single C38
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Small glutamine-rich tetratricopeptide repeat-containing protein alpha
Authors:Chartron, J.W, VanderVelde, D.G, Clemons Jr, W.M.
Deposit date:2012-08-19
Release date:2012-11-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2, 2012
4GOD
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BU of 4god by Molmil
Crystal structure of the SGTA homodimerization domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Small glutamine-rich tetratricopeptide repeat-containing protein alpha
Authors:Chartron, J.W, VanderVelde, D.G, Clemons Jr, W.M.
Deposit date:2012-08-19
Release date:2012-11-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2, 2012
4GOC
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BU of 4goc by Molmil
Crystal structure of the Get5 ubiquitin-like domain
Descriptor: Golgi to ER traffic protein 5
Authors:Chartron, J.W, VanderVelde, D.G, Clemons Jr, W.M.
Deposit date:2012-08-19
Release date:2012-11-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2, 2012
3EPM
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BU of 3epm by Molmil
Crystal structure of Caulobacter crescentus ThiC
Descriptor: 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SULFATE ION, Thiamine biosynthesis protein thiC, ...
Authors:Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-10-28
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.793 Å)
Cite:Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
3EPN
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BU of 3epn by Molmil
Crystal structure of Caulobacter crescentus ThiC complexed with imidazole ribonucleotide
Descriptor: 1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole, Thiamine biosynthesis protein thiC
Authors:Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E.
Deposit date:2008-09-29
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
1T79
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BU of 1t79 by Molmil
Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLW motif
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, FxxLW motif peptide
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-08
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T7F
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BU of 1t7f by Molmil
Crystal structure of the androgen receptor ligand binding domain in complex with a LxxLL motif
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, LxxLL motif peptide
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-10
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T7M
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BU of 1t7m by Molmil
Crystal structure of the androgen receptor ligand binding domain in complex with a FxxYF motif
Descriptor: 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ...
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-10
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T74
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BU of 1t74 by Molmil
Crystal structure of the androgen receptor ligand binding domain in complex with a WxxLF motif
Descriptor: 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ...
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-07
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
3NPZ
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BU of 3npz by Molmil
Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)
Descriptor: Prolactin, Prolactin receptor
Authors:Van Agthoven, J, England, P, Goffin, V, Broutin, I.
Deposit date:2010-06-29
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone.
J.Mol.Biol., 404, 2010
3KJR
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BU of 3kjr by Molmil
Crystal structure of dihydrofolate reductase/thymidylate synthase from Babesia bovis determined using SlipChip based microfluidics
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Dihydrofolate reductase/thymidylate synthase, GLYCEROL, ...
Authors:Li, L, Du, W, Edwards, T.E, Staker, B.L, Phan, I, Stacy, R, Ismagilov, R.F, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-11-03
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Multiparameter screening on SlipChip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods.
J.Am.Chem.Soc., 132, 2010
4INI
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BU of 4ini by Molmil
Human Histidine Triad Nucleotide Binding Protein 2 with Bound AMP
Descriptor: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Maize, K.M, Wagner, C.R, Finzel, B.C.
Deposit date:2013-01-04
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily.
Febs J., 280, 2013
1W1I
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BU of 1w1i by Molmil
Crystal structure of dipeptidyl peptidase IV (DPPIV or CD26) in complex with adenosine deaminase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Weihofen, W.A, Liu, J, Reutter, W, Saenger, W, Fan, H.
Deposit date:2004-06-22
Release date:2004-09-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface.
J. Biol. Chem., 279, 2004
4AJ5
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Crystal structure of the Ska core complex
Descriptor: SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1, SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2, SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3
Authors:Jeyaprakash, A.A, Santamaria, A, Jayachandran, U, Chan, Y.W, Benda, C, Nigg, E.A, Conti, E.
Deposit date:2012-02-15
Release date:2012-05-23
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structural and Functional Organization of the Ska Complex, a Key Component of the Kinetochore-Microtubule Interface.
Mol.Cell, 46, 2012

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