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4GL7
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BU of 4gl7 by Molmil
Structure of human placental aromatase complexed with designed inhibitor HDDG046 (compound 5)
Descriptor: (6alpha,8alpha)-6-(pent-2-yn-1-yloxy)androsta-1,4-diene-3,17-dione, Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ghosh, D.
Deposit date:2012-08-13
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55, 2012
1GB2
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BU of 1gb2 by Molmil
CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS
Descriptor: LYSOZYME, SODIUM ION
Authors:Funahashi, J, Takano, K, Yamagata, Y, Yutani, K.
Deposit date:2000-06-26
Release date:2000-07-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Biochemistry, 39, 2000
1GB9
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BU of 1gb9 by Molmil
CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS
Descriptor: LYSOZYME, SODIUM ION
Authors:Funahashi, J, Takano, K, Yamagata, Y, Yutani, K.
Deposit date:2000-06-26
Release date:2000-07-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Biochemistry, 39, 2000
4GLM
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BU of 4glm by Molmil
Crystal structure of the SH3 Domain of DNMBP protein [Homo sapiens]
Descriptor: Dynamin-binding protein, UNKNOWN ATOM OR ION
Authors:Dong, A, Guan, X, Huang, H, Tempel, W, Gu, J, Sidhu, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2012-08-14
Release date:2012-11-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the SH3 Domain of DNMBP protein [Homo sapiens]
to be published
4GN5
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BU of 4gn5 by Molmil
OBody AM3L15 bound to hen egg-white lysozyme
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, GLYCEROL, ...
Authors:Steemson, J.D, Liddament, M.T.
Deposit date:2012-08-16
Release date:2013-08-21
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Tracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-Fold.
Plos One, 9, 2014
4GLY
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BU of 4gly by Molmil
Human urokinase-type plasminogen activator uPA in complex with the two-disulfide bridge peptide UK504
Descriptor: BICYCLIC PEPTIDE INHIBITOR UK504, CHLORIDE ION, GLYCEROL, ...
Authors:Buth, S.A, Leiman, P.G, Chen, S, Heinis, C.
Deposit date:2012-08-15
Release date:2013-05-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.518 Å)
Cite:Bicyclic Peptide Ligands Pulled out of Cysteine-Rich Peptide Libraries.
J.Am.Chem.Soc., 135, 2013
1GDN
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BU of 1gdn by Molmil
FUSARIUM OXYSPORUM TRYPSIN AT ATOMIC RESOLUTION
Descriptor: GLY-ALA-LYS, GLYCEROL, SULFATE ION, ...
Authors:Rypniewski, W.R, Oestergaard, P, Noerregaard-Madsen, M, Dauter, M, Wilson, K.S.
Deposit date:2000-09-28
Release date:2001-02-07
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (0.81 Å)
Cite:Fusarium oxysporum trypsin at atomic resolution at 100 and 283 K: a study of ligand binding.
Acta Crystallogr.,Sect.D, 57, 2001
3QK3
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BU of 3qk3 by Molmil
Crystal structure of human beta-crystallin B3
Descriptor: 1,2-ETHANEDIOL, Beta-crystallin B3, SULFATE ION
Authors:Krojer, T, Gileadi, C, Cocking, R, Muniz, J, Pilka, E, Yue, W.W, Vollmar, M, Pike, A.C.W, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Kavanagh, K, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2011-01-31
Release date:2011-02-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:

1GF8
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BU of 1gf8 by Molmil
CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS
Descriptor: LYSOZYME, SODIUM ION
Authors:Funahashi, J, Takano, K, Yamagata, Y, Yutani, K.
Deposit date:2000-12-04
Release date:2000-12-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
J.Biol.Chem., 277, 2002
4GN4
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BU of 4gn4 by Molmil
OBody AM2EP06 bound to hen egg-white lysozyme
Descriptor: GLYCEROL, Lysozyme C, OBody AM2EP06
Authors:Steemson, J.D, Liddament, M.T.
Deposit date:2012-08-16
Release date:2013-08-21
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (1.861 Å)
Cite:Tracking Molecular Recognition at the Atomic Level with a New Protein Scaffold Based on the OB-Fold.
Plos One, 9, 2014
4GBQ
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BU of 4gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, 15 STRUCTURES
Descriptor: GRB2, SOS-1
Authors:Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
4GCR
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BU of 4gcr by Molmil
STRUCTURE OF THE BOVINE EYE LENS PROTEIN GAMMA-B (GAMMA-II)-CRYSTALLIN AT 1.47 ANGSTROMS
Descriptor: GAMMA-B CRYSTALLIN
Authors:Slingsby, C, Najmudin, S, Nalini, V, Driessen, H.P.C, Blundell, T.L, Moss, D.S, Lindley, P.
Deposit date:1992-04-02
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structure of the bovine eye lens protein gammaB(gammaII)-crystallin at 1.47 A.
Acta Crystallogr.,Sect.D, 49, 1993
1GI6
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BU of 1gi6 by Molmil
A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE
Descriptor: 2-(2-HYDROXY-PHENYL)-1H-INDOLE-5-CARBOXAMIDINE, BETA-TRYPSIN, CALCIUM ION, ...
Authors:Katz, B.A, Elrod, K, Luong, C, Rice, M, Mackman, R.L, Sprengeler, P.A, Spencer, J, Hatayte, J, Janc, J, Link, J, Litvak, J, Rai, R, Rice, K, Sideris, S, Verner, E, Young, W.
Deposit date:2001-01-22
Release date:2002-01-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.
J.Mol.Biol., 307, 2001
4GCH
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BU of 4gch by Molmil
STRUCTURE AND ACTIVITY OF TWO PHOTOREVERSIBLE CINNAMATES BOUND TO CHYMOTRYPSIN
Descriptor: 3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID, GAMMA-CHYMOTRYPSIN A
Authors:Stoddard, B.L, Ringe, D, Petsko, G.A.
Deposit date:1989-09-25
Release date:1990-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and activity of two photoreversible cinnamates bound to chymotrypsin.
Biochemistry, 29, 1990
1GMC
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BU of 1gmc by Molmil
THE X-RAY CRYSTAL STRUCTURE OF THE TETRAHEDRAL INTERMEDIATE OF GAMMA-CHYMOTRYPSIN IN HEXANE
Descriptor: GAMMA-CHYMOTRYPSIN A, PRO GLY ALA TYR PEPTIDE
Authors:Yennawar, N.H, Yennawar, H.P, Banerjee, S, Farber, G.K.
Deposit date:1993-08-20
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray crystal structure of gamma-chymotrypsin in hexane.
Biochemistry, 33, 1994
4ILZ
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BU of 4ilz by Molmil
Structural and kinetic study of an internal substrate binding site of dehaloperoxidase-hemoglobin A from Amphitrite ornata
Descriptor: 2,4,6-TRIBROMOPHENOL, Dehaloperoxidase A, ISOPROPYL ALCOHOL, ...
Authors:de Serrano, V.S, Zhao, J, Zhao, J, Franzen, S.
Deposit date:2013-01-01
Release date:2013-03-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural and Kinetic Study of an Internal Substrate Binding Site in Dehaloperoxidase-Hemoglobin A from Amphitrite ornata.
Biochemistry, 52, 2013
3QI1
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BU of 3qi1 by Molmil
Design and synthesis of hydroxyethylamine (hea) BACE-1 inhibitors: prime side chromane-containing inhibitors
Descriptor: Beta-secretase 1, N-[(2S,3R)-4-{[(2R,4S)-2-cyclopropyl-6-(2,2-dimethylpropyl)-3,4-dihydro-2H-chromen-4-yl]amino}-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]acetamide
Authors:Yao, N.
Deposit date:2011-01-26
Release date:2012-03-28
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
1GAZ
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BU of 1gaz by Molmil
Crystal Structure of Mutant Human Lysozyme Substituted at the Surface Positions
Descriptor: LYSOZYME, SODIUM ION
Authors:Funahashi, J, Takano, K, Yamagata, Y, Yutani, K.
Deposit date:2000-06-26
Release date:2000-07-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of amino acid residues at turns in the conformational stability and folding of human lysozyme.
Biochemistry, 39, 2000
1GB5
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BU of 1gb5 by Molmil
CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS
Descriptor: LYSOZYME, SODIUM ION
Authors:Funahashi, J, Takano, K, Yamagata, Y, Yutani, K.
Deposit date:2000-06-26
Release date:2000-07-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Biochemistry, 39, 2000
7Z39
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BU of 7z39 by Molmil
Structure of Belumosudil bound to CK2alpha
Descriptor: 2-[3-[4-(1~{H}-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-~{N}-propan-2-yl-ethanamide, ACETATE ION, Casein kinase II subunit alpha, ...
Authors:Brear, P, Hyvonen, M.
Deposit date:2022-03-01
Release date:2022-10-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the Rho-associated coiled-coil kinase 2 inhibitor belumosudil bound to CK2 alpha.
Acta Crystallogr.,Sect.F, 78, 2022
1GF0
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BU of 1gf0 by Molmil
BURIED POLAR MUTANT HUMAN LYSOZYME
Descriptor: LYSOZYME, SODIUM ION
Authors:Takano, K, Yamagata, Y, Yutani, K.
Deposit date:2000-11-30
Release date:2001-04-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Contribution of polar groups in the interior of a protein to the conformational stability.
Biochemistry, 40, 2001
4GPO
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BU of 4gpo by Molmil
Oligomeic Turkey Beta1-Adrenergic G Protein-Coupled Receptor
Descriptor: Beta-1 adrenergic receptor
Authors:Huang, J.J, Chen, S, Zhang, J.J, Huang, X.Y.
Deposit date:2012-08-21
Release date:2013-02-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of oligomeric beta-1-adrenergic G protein-coupled receptors in ligand-free basal state.
Nat.Struct.Mol.Biol., 20, 2013
1GBD
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BU of 1gbd by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E, Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GF6
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BU of 1gf6 by Molmil
BURIED POLAR MUTANT HUMAN LYSOZYME
Descriptor: LYSOZYME, SODIUM ION
Authors:Takano, K, Yamagata, Y, Yutani, K.
Deposit date:2000-11-30
Release date:2001-04-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Contribution of polar groups in the interior of a protein to the conformational stability.
Biochemistry, 40, 2001
1GFE
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BU of 1gfe by Molmil
CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS
Descriptor: LYSOZYME, SODIUM ION
Authors:Funahashi, J, Takano, K, Yamagata, Y, Yutani, K.
Deposit date:2000-12-04
Release date:2000-12-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
J.Biol.Chem., 277, 2002

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